The Value of Second Opinion in Gastrointestinal and Liver Pathology

2001 ◽  
Vol 125 (6) ◽  
pp. 736-739 ◽  
Author(s):  
Geoffrey K. Hahm ◽  
Theodore H. Niemann ◽  
Joel G. Lucas ◽  
Wendy L. Frankel
Keyword(s):  
Clinical Significance ◽  
Medical Center ◽  
Ohio State University ◽  
Second Opinion ◽  
State University ◽  
Missing Information ◽  
Additional Information ◽  
Pertinent Information ◽  
Impact On Treatment ◽  
Pathology Reports

Abstract Objective.—The value of routine second opinion review of liver and gastrointestinal pathologic material was evaluated to determine whether there were discrepancies in diagnoses and if these discrepancies had an impact on treatment or prognosis. Materials and Methods.—All gastrointestinal and hepatobiliary histopathology referral diagnoses made during a 1-year period for patients being treated at Ohio State University Medical Center were compared with the outside pathologic diagnosis. All major discrepant diagnoses were reviewed by at least 2 pathologists. Diagnoses were classified as no diagnostic disagreement, diagnostic disagreement, or no diagnostic disagreement but pertinent information missing or terminology unclear. Discrepant cases were also classified according to the clinical significance of the discrepancy. Results.—Pathology reports from 194 hepatobiliary and gastrointestinal cases were reviewed. Of the hepatobiliary cases, 57 (64.8%) of 88 cases showed no discrepancies. Discrepancies were noted in 31 cases (35.2%), including missing information or unclear terminology in the diagnosis in 23 cases (26.1%) and diagnostic disagreement in 8 cases (9.1%). Of the cases with discrepancies, 6 (6.8%) were of major significance. Of the gastrointestinal cases, 87 (82.1%) of 106 cases showed no discrepancies. Discrepancies were noted in 19 cases (17.9%), including missing or unclear information in 3 cases (2.8%) and diagnostic disagreements in 16 cases (15.1%). The cases with discrepancies included 8 cases (7.5%) for which the change was of major clinical significance. Conclusions.—Routine pathologic review of gastrointestinal and hepatobiliary cases revealed notable discrepancies in diagnoses. In 14 cases (7.2%), the change in diagnosis or additional information had a significant effect on the proper treatment or a significant prognostic implication. Routine review of all pertinent pathologic material should be performed on all patients being transferred to a second institution for treatment or second opinion.

NEWS AND ANNOUNCEMENTS

PEDIATRICS ◽  
1959 ◽  
Vol 23 (1) ◽  
pp. 179-183
Keyword(s):  
Medical Center ◽  
Ohio State University ◽  
City Hospital ◽  
State University ◽  
University Of Michigan ◽  
Contagious Diseases ◽  
Ann Arbor ◽  
The University ◽  
Vanderbilt University ◽  
Michigan Medical

Postgraduate Courses—AAP The first two of a series of postgraduate courses being sponsored by the American Academy of Pediatrics will be held at the University of Michigan Medical Center, Ann Arbor, Michigan, March 2, 3, 4, and 5, 1959; and at Vanderbilt University Medical Center, Nashville, Tennessee, on March 17, 18, and 19, 1959. Tuition for these courses is $50 and $40, respectively, for Academy members. Fees for nonmembers will be $70 and $60, respectively. These courses will both be organized so that each day will be devoted to papers and discussions on a different pediatric problem. At the University of Michigan, Dr. James Wilson and the pediatric staff will be hosts, as well as part of the faculty for the course. Other speakers will include members of other departments and the guest speakers, Dr. Warren Wheeler, Professor of Pediatrics and Bacteriology, Ohio State University Medical School, and Dr. Frederick C. Robbins, Director, Department of Pediatrics and Contagious Diseases, Cleveland City Hospital.

Pharmacy Issues: Intravenous Drug Ordering

2001 ◽  
Vol 36 (3) ◽  
pp. 329-332
Author(s):  
Alicia S. Miller
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Medical Center ◽  
Ohio State University ◽  
Intravenous Drug ◽  
State University ◽  
Order Entry ◽  
The Status ◽  
Practical Information ◽  
The Ohio State University

This continuing feature will inform readers about the process of implementing, maintaining, and supporting prescriber computer order entry (PCOE) at the Ohio State University Medical Center. (By “prescribers,” we refer to health care professionals authorized to prescribe medications by their states.) Practical information on what worked and what failed will be provided, along with current updates on the status of PCOE at the Medical Center.

Pharmacy Issues: Weight-Based Dosing

2001 ◽  
Vol 36 (7) ◽  
pp. 790-791
Author(s):  
Alicia S. Miller
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Medical Center ◽  
Ohio State University ◽  
State University ◽  
Order Entry ◽  
The Status ◽  
Practical Information ◽  
The Ohio State University

This continuing feature will inform readers about the process of implementing, maintaining, and supporting prescriber computer order entry (PCOE) at the Ohio State University Medical Center. (By “prescribers,” we refer to health care professionals authorized to prescribe medications by their states.) Practical information on what worked and what failed will be provided, along with current updates on the status of PCOE at the Medical Center.

scholarly journals Using Metabolomics to Classify the Underlying Effects of Multi-Nutrient Supplementation in ADHD Youth

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1351-1351
Author(s):  
Madeline Stern ◽  
Leanna Perez ◽  
Jeanette Johnstone ◽  
Barbara Gracious ◽  
Brenda Leung ◽  
...  
Keyword(s):  
Medical Center ◽  
Ohio State University ◽  
State University ◽  
Adhd Symptoms ◽  
Open Label ◽  
Nutrient Supplementation ◽  
Open Label Phase ◽  
The Ohio State University ◽  
Double Blinded

Abstract Objectives Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder commonly diagnosed in childhood. Current pharmaceutical treatment options provide a poor long-term risk: benefit ratio with little knowledge of the long-term effects. A broad-spectrum multi-nutrient formula has shown promise in children, but its effects on nutrient status and the underlying metabolome interactions have not been characterized. Methods Blood samples from medication-free children (n = 74) with ADHD enrolled in a double–blind randomized placebo-controlled multinutrient trial (RCT) were collected at baseline and 8 weeks post-intervention. Following RCT is an 8-week open label phase during which all participants took the active supplement. Symptoms were assessed using the Child and Adolescent Symptom Inventory 5. Double-blinded plasma samples will be analyzed for tyrosine, phenylalanine, tryptophan, magnesium, and zinc. Untargeted LC-MS metabolomics using HILIC chromatography and a high resolution QTof will assess very polar analytes in plasma extracts. Linear modeling will elucidate the influence of treatment, sampling time, and ADHD symptom score on plasma nutrient and plasma metabolite concentration. Results Preliminary findings of the open label phase show a significant improvement in inattention (P = 0.0435), hyperactivity (P = 0.0068), ODD (P = 0.0108) and DMDD (P = 0.0119). We hypothesize that these improvements in ADHD symptoms will be correlated with increased circulating concentrations of tyrosine, phenylalanine, tryptophan, magnesium, zinc, and metabolites involved in neurotransmitter synthesis and/or branched chain amino acid metabolism. Conclusions Preliminary findings indicate improvements of ADHD symptoms of inattention, hyperactivity, ODD and DMDD following 8 weeks of open label multi-nutrient supplementation. Results of the double-blinded phase are expected to mirror those observed in the open label phase, with increases in nutrients in those receiving the multinutrient. Funding Sources The sample analyses were supported by NIH Award Number Grant P30 CA016058, OSU, and OSUCCC. Foundation for the Center of Excellence in Mental Health, Canada; The Ohio State University Department of Human Sciences, College of Education and Human Ecology; The Ohio State University Wexner Medical Center, Clinical Research Center.

The Training Process (Part 1)

2003 ◽  
Vol 38 (1) ◽  
pp. 84-88 ◽  
Author(s):  
Alicia S. Miller
Keyword(s):  
Health Care Professionals ◽  
Medical Center ◽  
Ohio State University ◽  
State University ◽  
Order Entry ◽  
Training Process ◽  
The Status ◽  
Practical Information ◽  
The Ohio State University ◽  
Computerized Prescriber Order Entry

This continuing feature will inform readers about the process of implementing, maintaining, and supporting computerized prescriber order entry (CPOE) at the Ohio State University Medical Center. (By “prescribers,” we refer to health care professionals authorized to prescribe medications by their states.) Practical information on what worked and what failed will be provided, along with current updates on the status of CPOE at the Medical Center.

Neonatal Intensive Care Unit Pathway

2003 ◽  
Vol 38 (8) ◽  
pp. 794-797
Author(s):  
Alicia S. Miller
Keyword(s):  
Health Care Professionals ◽  
Neonatal Intensive Care ◽  
Medical Center ◽  
Ohio State University ◽  
State University ◽  
Order Entry ◽  
The Status ◽  
Practical Information ◽  
The Ohio State University ◽  
Computerized Prescriber Order Entry

This continuing feature will inform readers about the process of implementing, maintaining, and supporting computerized prescriber order entry (CPOE) at the Ohio State University Medical Center. (By “pre-scribers,” we refer to health care professionals authorized to prescribe medications by their states.) Practical information on what worked and what failed will be provided, along with current updates on the status of CPOE at the Medical Center.

Urinary Incontinence in Juvenile Female Soft-Coated Wheaten Terriers: Hospital Prevalence and Anatomic Urogenital Anomalies

2016 ◽  
Vol 52 (1) ◽  
pp. 27-35 ◽  
Author(s):  
Jason Callard ◽  
Mary A. McLoughlin ◽  
Julie K. Byron ◽  
Dennis J. Chew
Keyword(s):  
Urinary Incontinence ◽  
Medical Center ◽  
Clinical Signs ◽  
Ohio State University ◽  
State University ◽  
Inclusion Criteria ◽  
Related Disorder ◽  
Juvenile Female ◽  
The Ohio State University ◽  
Ectopic Ureters

Urinary incontinence in juvenile female dogs is often associated with urogenital anatomic anomalies. Study objectives include: (1) determine hospital prevalence of urinary incontinence in juvenile female soft-coated wheaten terriers (SCWTs) compared to other affected dogs; (2) characterize anatomic anomalies affecting urinary incontinent juvenile female SCWTs utilizing uroendoscopy; and (3) compare incidence of ectopic ureters, paramesonephric remnants, and short urethras in juvenile female urinary incontinent SCWTs to other juvenile female dogs with urinary incontinence. We hypothesize juvenile SCWTs have an increased prevalence of urinary incontinence and an increased incidence of ectopic ureters, paramesonephric remnants, and short urethras compared to non-SCWTs with urinary incontinence within our hospital population. Medical records of female dogs 6 mo of age and younger with clinical signs of urinary incontinence and video uroendoscopic evaluation presenting to The Ohio State University Veterinary Medical Center from January 2000 to December 2011 were reviewed. Twelve juvenile SCWTs and 107 juvenile non-SCWTs met the inclusion criteria. Juvenile SCWTs were found to have an increased hospital prevalence of urinary incontinence compared to other affected breeds. Observed anomalies in SCWTs include: ectopic ureters, shortened urethras, paramesonephric remnants, and bifid vaginas. This information will help guide veterinarians in recognizing a breed-related disorder of the lower urogenital tract in SCWTs.

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