Drug utilization evaluation of psychotropic drugs in the psychiatry in-patient department of Tertiary care hospital

Background: Geriatrics tend to be the largest consumers of prescribed drugs exposing them to various drug interactions and adverse drug reactions. Present study is an attempt to assess the drug utilization pattern of psychotropic drugs among the geriatrics in psychiatry out-patient department (OPD) of a tertiary care hospital in Kerala.Methods: Prescriptions of patients diagnosed with psychiatric illness and being prescribed at least one psychotropic drug were collected. Prescriptions of male and female patients of age more than 60 years were sorted and analysed separately according to WHO core prescribing indicators.Results: 18% prescriptions were of geriatric population. Depressive disorders (38.89%) were the most common psychiatric disorder encountered. Out of 291 drugs prescribed in geriatrics, 237(81.44%) drugs were psychotropic drugs. Among the total psychotropic drugs prescribed, antipsychotics (39.24%) were the most commonly prescribed class of drugs. Average number of psychotropic drugs per prescription was 2.19, drugs prescribed by generic name were 2.06% and the drugs prescribed from NLEM (2015) were 41.77%. 86.11% of prescriptions contained more than one drug and 33.33% of prescriptions contained FDCs.Conclusions: Prescription analysis using WHO prescribing indicators showed some deviations from the standard which can be improved. A trend of polypharmacy was noted in this study. Prescribing using generic name and prescribing from NLEM was low as compared to the other reference studies. Proper strategies taken to overcome the inadequacies pointed out by this study can ensure the rational use of medicines.

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A Retrospective Drug Utilization Study on Psychiatric Illness in a Tertiary Care Teaching Hospital

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i40b32274 ◽

2021 ◽

pp. 148-153

Author(s):

I. Jerlin Michelle ◽

E. Dhanushri ◽

V. Nidhish RAJ ◽

Muhammad Aslam Syed ◽

A. Priyadharshini ◽

...

Keyword(s):

Drug Utilization ◽

Psychotropic Drugs ◽

Psychiatric Illness ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Prescribing Pattern ◽

Increased Risk ◽

Drug Utilization Studies ◽

Standard Value

Psychiatric disorders are now widely recognized as a major contributor to the global burden of disease. It has been described that there is an increased risk of adverse effects when more than one psychotropic drug is prescribed. Knowledge of the pattern of utilization of drugs in the general population can be achieved through the conduct of drug utilization studies. The present study has therefore been conducted to observe the pattern of drug use in psychiatry patients in a tertiary care hospital. Aim and Objective: To assess the epidemiology of various psychiatric illnesses among the study population To assess the Prescribing Pattern of drugs in Psychiatric Illness. To assess the drug-drug interactions in the prescription using MICROMEDEX. Methodology: A retrospective descriptive observational study was performed in a tertiary care hospital. A total of 100 prescriptions were collected from MRD. Results: The study reported that 66% of patients were males and 34% were females. The average number of drugs and psychotropic drugs per prescription is six and four respectively. Around 61.98% of drugs in the prescription are psychotropic drugs, among that 40.17% of benzodiazepines are majorly used, followed by 34.27% of antipsychotics. Almost 95 prescriptions had a minimum of one drug-drug interaction. The average number of psychotropics per prescription was higher than in studies. The average number of drugs per prescription was 5.84, which lead to polypharmacy. Conclusion: Using WHO indicators prescription analysis was done and it showed some deviation from the standard value which can be improved. Polypharmacy was noted in this study. Most of the drug is prescribed in the brand name which should be avoided.

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A study on drug utilization evaluation of antibiotics in tertiary care hospital

International Journal of Pharmaceutical Research and Life Sciences ◽

10.26452/ijprls.v8i2.1286 ◽

2020 ◽

Vol 8 (2) ◽

pp. 53-59

Author(s):

Sesham Pushpalatha ◽

Dheeravath Swapna ◽

Antarvedi Moshe ◽

Nagam Venkata Sai Jyothirmai ◽

Tatipamula Vasundhara ◽

...

Keyword(s):

Drug Utilization ◽

Average Cost ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Utilization Review ◽

Care Hospital ◽

Prescribing Pattern ◽

Rational Use ◽

Rational Use Of Antibiotics ◽

Drug Utilization Evaluation

Studies like Drug utilization evaluation have an essential role in finding a prescription pattern of drugs prescribed in hospital for the rational use of antibiotics. An observational study conducted in a tertiary care hospital for six months among 200 patients. The study was conducted to assess prescribing pattern, the average cost of antibiotics prescribed. Also, the ten most commonly prescribed antibiotic’/ 100bed- days and ATC were calculated. Most commonly prescribed antibiotic was , followed by /. The average cost was Rs. 2742.5±25135.19 for the prescribed antibiotics. Pharmacists and physicians play a significant role in decreasing patient problems and the problems related to antibiotics by creating awareness programs related standard prescribing guidelines in the hospital, which results in a reduction of the antibiotic resistance. it is essential to carry out a drug utilization review to study the rational use of antibiotics.

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