Histopathological study of soft tissue tumors: A three year experience in tertiary care centre

Background: Soft tissue tumors are a diverse group of lesions arising from the supporting soft tissue of the body. Though pathologically diverse, they frequently exhibit similar clinical presentations and radiological features. Correct histopathological diagnosis is therefore crucial for further management. Aim/Objectives: To evaluate the spectrum of benign as well as malignant soft tissue tumors in a tertiary care centre in North India. Material and Methods: This retrospective study was carried out in the Department of Pathology from April 2017 to March 2018. All cases of soft tissue tumors in this period were included in the study. Gross findings were recorded from Histopathology request forms. Histology slides stained with haematoxylin and eosin stain were reviewed and findings recorded. Results: Majority of patients were males with maximum cases in the 4th decade. Of all soft tissue tumors, 90.4% were benign, 4.0 % intermediate and 5.6% were malignant. Benign Adipocytic tumors (48.0%) were the commonest soft tissue tumors, followed by benign vascular tumors (24.0%). Malignant Fibrous Histiocytoma was the commonest malignant neoplasm in our study (42.8 %). Conclusions: Soft tumors pose diagnostic challenges because of confounding morphological characteristics. The incidence of benign tumors (90.4%) was much higher than malignant tumors in our study with benign lipomatous tumors (48.0%) being most common tumors. Keywords: Histopathology; Tumors; Lipomatous; Malignant

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A PROSPECTIVE HISTOPATHOLOGICAL STUDY OF MENINGIOMAS IN A TERTIARY CARE CENTRE OF VIJAYAWADA

10.36106/gjra/9100428 ◽

2021 ◽

pp. 11-13

Author(s):

C.Bhanu Sree ◽

P. Annapurna ◽

M. Rajani

Keyword(s):

Surgical Resection ◽

Tertiary Care ◽

Histopathological Study ◽

Age Group ◽

Care Centre ◽

Tertiary Care Centre ◽

Medical College ◽

Histological Appearance ◽

Classi Cation ◽

A Prospective Study

Background: Meningiomas are neoplasms arising from the arachnoidal cap cells in the meningeal coverings of the spinal cord and brain. These are the most common benign intracranial tumours and account for about 13-26% of all primary brain neoplasms. These are generally benign neoplasms of adults most often seen in middle age, but about 10% are atypical or malignant. These neoplasms are graded by WHO as Grade I , II and III . Benign meningiomas can be cured by surgical resection where as higher grade meningiomas require radiotherapy after surgical resection as these higher grade meningiomas have greater recurrence and aggressive behavior. Aims and Objectives: To study the variants and histopathological spectrum of meningioma and prognosis of variants. Material & Methods: The present study is a prospective study conducted in the department of Pathology, Siddhartha medical college from June 2019-May 2020. During this study, 16 cases of meningiomas were diagnosed and reviewed. Result:In our study of 16 cases females were 62.5%. The most common age group is 41-60 yrs (68.75%). Most common variant was noted to be transitional meningioma followed by meningothelial meningioma. Out of the 16 cases, grade I were 81.25%. Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient's prognosis. Hence a continuous revision of histopathological classication systems is required to improve the diagnostic accuracy. Benign meningiomas are the most common type. From our study, we conclude that transitional meningioma is the most common benign variant.

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