A PROSPECTIVE HISTOPATHOLOGICAL STUDY OF MENINGIOMAS IN A TERTIARY CARE CENTRE OF VIJAYAWADA

2021 ◽  
pp. 11-13
Author(s):  
C.Bhanu Sree ◽  
P. Annapurna ◽  
M. Rajani

Background: Meningiomas are neoplasms arising from the arachnoidal cap cells in the meningeal coverings of the spinal cord and brain. These are the most common benign intracranial tumours and account for about 13-26% of all primary brain neoplasms. These are generally benign neoplasms of adults most often seen in middle age, but about 10% are atypical or malignant. These neoplasms are graded by WHO as Grade I , II and III . Benign meningiomas can be cured by surgical resection where as higher grade meningiomas require radiotherapy after surgical resection as these higher grade meningiomas have greater recurrence and aggressive behavior. Aims and Objectives: To study the variants and histopathological spectrum of meningioma and prognosis of variants. Material & Methods: The present study is a prospective study conducted in the department of Pathology, Siddhartha medical college from June 2019-May 2020. During this study, 16 cases of meningiomas were diagnosed and reviewed. Result:In our study of 16 cases females were 62.5%. The most common age group is 41-60 yrs (68.75%). Most common variant was noted to be transitional meningioma followed by meningothelial meningioma. Out of the 16 cases, grade I were 81.25%. Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient's prognosis. Hence a continuous revision of histopathological classication systems is required to improve the diagnostic accuracy. Benign meningiomas are the most common type. From our study, we conclude that transitional meningioma is the most common benign variant.

2012 ◽  
Vol 32 (2) ◽  
pp. 142-145 ◽  
Author(s):  
B Sigdel ◽  
R Nepali

Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673


2018 ◽  
Vol 6 (2) ◽  
pp. 42-44
Author(s):  
B Sharma ◽  
A Devkota ◽  
SC Pant

Introduction: Study on prevalence of psychiatric disorders in Palpa and nearby districts which lie in western Nepal, is not much studied till date. We therefore conducted this study aiming to see the pattern of psychiatric illness in an Outpatient Department of Lumbini Medical College which is a tertiary care centre located in Palpa district.Material And Method: : This is a retrospective study where outpatient record of all new cases attending the Psychiatry OPD from 29th Oct 2014 to 29th Dec 2014 were studied and statistical analysis were done. The number of new patients were 107.Results: Out of 107 patients, 60.74 % (65)) were females and 39.26 %( 42) were males. Patients of age group 31-40yrs showed the largest proportion (27.49%) followed by age group 41-50yrs (24.29%). Majority cases were illiterate (69.15%) followed by primary level of education (14.95%). The occupation of most of the cases were household work (35.51%) followed by farming (31.77%). Anxiety disorder (27.10%) was the most frequent diagnosis ahead of “Others” (18.69%) followed by depressive disorder (15.88%).Conclusion: Most of the new patients attending the psychiatry OPD of Lumbini Medical College were females, of 31-40 age group and most of the patients suffered from anxiety disorders. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017, Page: 42-44


2016 ◽  
Vol 5 (1) ◽  
pp. 26-31
Author(s):  
Ram Hari Ghimire

Background Studies on clinical characteristics and upper gastrointestinal endoscopic findings of the cirrhotic patients in a tertiary care centre are sparse from eastern region of Nepal. The aim was to profile these patients clinically and analyse the endoscopic findings.Material and Methods This was a cross-sectional analytical study carried out in the Department of Medicine of Nobel Medical College, Biratnagar from 30st September 2012 to 30th August 2013(one year). After admission, detail medical history and meticulous clinical examination was carried out in every patient with clinical diagnosis of cirrhosis of liver. Routine, biochemical, hematological, imaging and special investigations were sent as per clinical scenario. Upper gastrointestinal endoscopy was carried out in all patients. Basic descriptive statistics were used to present the data.Results A total of 104 patients were enrolled in our study. The mean age was 50.09 years ± 11.79 (Range 26-79), of which 60% were males. Almost 70% of the patients were from productive age group (31-70 years). All the patients were symptomatic. Chronic excessive alcohol consumption was the commonest cause of cirrhosis (80.76%). The major clinical presentations were ascites (83.65%) and jaundice (79.92%). Pedal edema was the commonest (85.6%) presenting sign. Diabetes mellitus and pneumonia were common comorbidities. Gastroesophageal varices were commonest (70.19%) endoscopic finding.Conclusion Cirrhotic patients presented late with complete decompensation in the form of ascites, jaundice and upper gastrointestinal bleeding from esophageal varices. Mostly people with productive age group were affected.Journal of Nobel Medical College Volume 5, Number 1, Issue 8, January-July 2016, 26-31 


2020 ◽  
pp. 1-3
Author(s):  
Aloke Mazumder ◽  
Umme S Faisal ◽  
Partha Pratim Mukhopadhyay ◽  
Amartya Chatterjee

Present study has been conducted at Department of Forensic Medicine and Toxicology, Malda Medical College, located at Malda District of West Bengal state that covers both international and state borderand having a different socio economic scenario than rest of the country which is often reflected at the pattern of medicolegal cases reported here. On the other hand, death of a female subject of medicolegal category bears definite implication on such aspects. In view of this one year autopsy based study has been conducted where out of 1685 autopsies, 562 cases were of female subjects. It has been seen that majority of unnatural deaths of females were due to effects of Hanging ( 26.87% ) , followed by Burn (19.93%) and intake of Poison (15.12% ). As per the age group is concerned, commonest age group affected was 16- 20 yrs ( 23.13%), followed by 21- 25 yr ( 14.95%). Highest incidence of such deaths took place in the month of October ( 11.21%) followed closely by August and September. Besides implementing mass awareness program on it, a collaborative research team comprising of Medicos, Judiciary and Police Authority is required to minimize such fatal outcomes of females.


Author(s):  
Muthuprabha P.

Background: The aim of this study was to study the prevalence of GDM in a tertiary care centre based on 75 gm OGCT and to analyse the socio demographic and clinical profile of GDM using 75 gm OGCT in a tertiary care centre.Methods: This study was conducted in the antenatal OPD of Tirunelveli Medical College Hospital from October 2014 to July 2015, a period of 10 months on 300 antenatal women. The mothers were screened using 75gm 2-hour OGCT once during each trimester and the results analysed.Results: The prevalence of GDM in this study was 3.4%. Out of this 47-50% of women with GDM were of the age group 26-30 years. 6% of the women had BMI of >25 kg/m2. The incidence of GDM was found to be high in multigravidas and 70% belonged to class V socioeconomic status. Using the 75 gm OGTT 20%, 40% and 40% were diagnosed during the I, II and III trimesters respectively. 90% of the women delivered at term and total caesarean section rate was 30.6%. Mean birth weight of the babies was 2.9 kg. 70% of the diagnosed GDM women were treated using Medical Nutrition Therapy (MNT).Conclusions: 75gm OGCT recommended by WHO can be used to detect significant number of cases of GDM.


Author(s):  
Navya Sri Sreenivas ◽  
Saraswathi Sakranaik ◽  
Ranganath Thimmanahalli Sobagiah ◽  
Anil Kumar

Background: Rabies is a viral zoonosis. In up to 99% of cases, domestic dogs are responsible for rabies virus transmission to humans. About 30% of the victims of dog bites are children under the age of 15. Ironically, all these problems are preventable by effective vaccination. However, for an ef­fective prevention programme, it is important to un­derstand the epidemiology of animal bite cases. The objective of the study was to assess the epidemiological pattern of animal bite cases attending anti-rabies clinic. Methods: A record based retrospective study was conducted from April to May 2016 by reviewing the records of one year in anti-rabies clinic. Results: In the study out of 2850 bite victims, 78% were males and about 21, 54% were in the age group of 20-29 years. 97% of cases were bitten by dog. Based on area wise distribution majority of the bite victims were from Bangalore west (49.5%), among them 23% was referred for Immunoglobulin. The study also showed that majority of paediatric cases were reported more during the month of April and May. Conclusions: In our study we found that majority of cases were reported among the paediatric age group during summer vacations. Hence education should be given in the community as well in schools for primary prevention of animal bite. 


2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Vani Chandrashekar

The aim of this study was to identify common stool parasites in patients attending a tertiary care centre in South India. We evaluated 2355 stool samples and parasites were detected in 7.9% of samples. 41.1% of our patients were in the 45–58-year age group. Protozoal infections were the commonest seen in 7.8% of samples. Entamoeba histolytica was the commonest protozoa (4.6%) followed by Entamoeba coli (1.2%) and Giardia (0.8%). Entamoeba histolytica and Entamoeba coli were together seen in 0.63%, and they were the commonest organisms seen in samples with multiple-organism infection. Both were equally detected in diarrheal samples.


2021 ◽  
pp. 80-81
Author(s):  
Vandana Parasar ◽  
Vidyabhushan Kumar ◽  
Ankita Singh ◽  
Nilesh Mohan

To determine the prevalence and occurrence of visual morbidity in patients of pterygium attending eye opd in a tertiary care centre of Bihar. Methods: In this observational study a total of 193 patients, diagnosed with pterygium, underwent complete ocular examination by an ophthalmologist. Epidemiological trends including age, sex, occupation, effect of living condition and socioeconomic status were analyzed. Results: There is a male preponderance of 58.03%. The age incidence of the group showed that the incidence of pterygium was 10.36% in the age group of less than 30 years. It rises to a maximum of 29.53% in the age of 41-50 years and then gradually declines.. The incidence was found to be maximum among farmers(39.86%) followed by miners(31%). Conclusion: People who work outdoors are at a greater risk because they are subjected to involuntary UVB exposure. The highest exposure occurs during the two hours on either side of noon. Workers must be aware and should take appropriate measures like wearing protective glasses, caps, etc


2021 ◽  
pp. 65-66
Author(s):  
R. K. Maurya ◽  
Shraddha Verma ◽  
R. K. Tripathi ◽  
Amit Yadav

Background: Hypospadias is a common congenital anomaly in which the anterior urethra is incompletely developed and does not extend to the tip of the glans penis. The present study was aimed to study the clinical prole of hypospadias. Settings and Design:This was a prospective, observational study. Methods: This prospective study was conducted at Department of General Surgery, LLR & Associated Hospitals, GSVM Medical College, Kanpur, India, from January 2019 to October 2020, on 72 patients of hypospadias, after taking clearance from the Institutional Ethical Committee, and taking proper informed consent for participation. Data collected for each patient included age, sex, demography, symptoms with duration, and relevant past and treatment history. Results: The most common age of presentation was between 1-5years of age (48.61%, n=35). Distal hypospadias (DH) was the most common site. (47.22%, n=34). 4.16% (n=3) patients presented with urethrocutaneous stula. Chordee was more commonly seen in patients with mid & proximal penile hypospadias (64.70%, n=33). In the present study, 4.1% (n=3) had associated undescended testis, 4.1% (n=3) had an associated bid scrotum and 1.3% (n=1) had an associated congenital hernia. Conclusions: Most cases of hypospadias present before 10 years of age. Distal hypospadias is the most common type. Chordee is associated most commonly with proximal penile and mid penile hypospadias. It may also be associated with other congenital anomalies like, undescended testis, bid scrotum or congenital hernias


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