Metastatic Malignant Melanoma of the Inguinal Lymph Node with Unknown Primary Lesion: A Case Report

2017 ◽  
Vol 3 (2) ◽  
pp. 13
Author(s):  
Guddi Rani Singh ◽  
Jiut Ram Keshari ◽  
Bhim Ram ◽  
Vijayanand choudhary ◽  
Ravi Bhushan Raman
2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Sherif Ali Eltawansy ◽  
Ryane Panasiti ◽  
Samaa Hasanien ◽  
Dennis Lourdusamy ◽  
David Sharon

Background. Malignant melanoma could present with metastasis with unknown primary (MUP) and this happens in 2-3% according to the studies. Around 90% of melanomas have cutaneous origin, but still there are melanomas that could be found in visceral organs or lymph nodes with unknown primary site. Spontaneous regression of the primary site could be an explanation.Case Report. We report a 58-year-old Caucasian male who presented with a right sided swelling in the inguinal region. Surgery was performed and biopsy showed metastatic malignant melanoma. No cutaneous lesions were identified by history or physical examination. Work up could not detect the primary lesion and patient was started on radiotherapy and immunotherapy.Conclusion. We present a case of malignant melanoma of unknown primary presenting in an unusual place which is the inguinal lymph node. Theories try to explain the pathway of development of such tumors and one of the theories mentions that it could be a spontaneous regression of the primary cutaneous lesion. Another theory is that it could be from transformation of aberrant melanocyte within the lymph node. Prognosis is postulated to be better in this case than in melanoma with a known primary.


2018 ◽  
Vol 8 (3) ◽  
pp. 174-176
Author(s):  
Debasish Das ◽  
Deb Prosad Paul ◽  
Kazi Sohel Iqbal

Malignant melanoma develops from the pigment containing cells known as melanocytes. Melanoma is more common in men than in women. It is found typically in the skin. It is also found in the mouth, intestine, eye and other sites. Melanoma may develop from a mole with changes including an increasing in size, irregular edges, changes in color, itchiness or skin breakdown. Prognosis is poor if it is not treated early. The primary cause of melanoma is UV light exposure. Patients with history of affected family members and poor immune function are at greater risk. Diagnosis is by biopsy from any affected skin lesion. Recurrence is common even many years after the initial diagnosis. Here we present a case of malignant melanoma of the inguinal lymph node with unknown primary lesion. Surgery was done with complete excision of inguinal lymph node. Biopsy report showed metastatic malignant melanoma.J Enam Med Col 2018; 8(3): 174-176


1990 ◽  
Vol 1 (2) ◽  
pp. 116
Author(s):  
Junji Nakano ◽  
Takashi Imamura ◽  
Sumiko Hamanaka ◽  
Takahisa Ota ◽  
Chidori Asagami

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