scholarly journals Management of Chronic Respiratory Failure in Interstitial Lung Diseases: Overview and Clinical Insights

2019 ◽  
Vol 16 (7) ◽  
pp. 967-980 ◽  
Author(s):  
Paola Faverio ◽  
Federica De Giacomi ◽  
Giulia Bonaiti ◽  
Anna Stainer ◽  
Luca Sardella ◽  
...  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Paola Faverio ◽  
Federica De Giacomi ◽  
Luca Sardella ◽  
Giuseppe Fiorentino ◽  
Mauro Carone ◽  
...  

2020 ◽  
pp. 4282-4291
Author(s):  
Michael I. Polkey ◽  
P.M.A. Calverley

Chronic respiratory failure describes a clinical state when the arterial Po2 breathing air is less than 8.0 kPa, which may or may not be associated with hypercapnia (defined as Pco2 more than 6.0 kPa (45 mm Hg)). Four processes cause arterial hypoxaemia due to inefficient pulmonary gas exchange—ventilation–perfusion (V/Q) mismatch, hypoventilation, diffusion limitation, and true shunt, with the most important of these being V/Q mismatching. The arterial CO2 is increased by inadequate alveolar ventilation and/or V/Q abnormality. A wide range of disorders can cause chronic respiratory failure, with the commonest being chronic obstructive pulmonary disease, interstitial lung diseases, chest wall and neuromuscular diseases, and morbid obesity.


CHEST Journal ◽  
2018 ◽  
Vol 154 (4) ◽  
pp. 450A
Author(s):  
PAOLA FAVERIO ◽  
SILVIA GAMBERINI ◽  
LAURA CATTANEO ◽  
ALMERICO MARRUCHELLA ◽  
GIUSEPPE PACIOCCO ◽  
...  

Author(s):  
Terry Robinson ◽  
Jane Scullion

The interstitial lung diseases (ILDs), are an extensive range of lung diseases, rather than a single disease entity. These diseases are often grouped together because they have similarities in clinical presentation, radiographic changes, physiological features, and symptoms. Despite their similarities, these diseases have a variety of aetiologies, treatments, and prognoses. The rate of onset of symptoms is very variable. Some patients present with long-standing radiological symptoms, often found opportunistically. Other patients present with acute onset symptoms, rapidly developing respiratory failure and ultimately progressing to death. This chapter covers the presentation, clinical findings, diagnosis, common causes, and associated investigations. Common ILDs are also described.


Author(s):  
O. D. Ostroumova ◽  
A. I. Listratov ◽  
A. I. Kochetkov ◽  
D. A. Sychev

Interstitial lesion is one of the causes of respiratory failure. Drugs are a modifiable etiological factor of lung damage. Medications most commonly associated with drug-induced interstitial lung disease include antineoplastic drugs, disease-modifying anti-rheumatic drugs and amiodarone. According to the latest literature data, the previously described link between anti-rheumatic drugs and interstitial lung diseases is very inconsistent. It may even be a protective effect of this group of drugs on the lung tissue. The relationship between statin use and interstitial lesions is also complex and not fully understood. It is necessary to carefully assess the appearance of respiratory tract complaints in patients taking statins as in other groups of patients. Prescription of additional diagnostic methods is necessary to close monitoring and prevention the toxic effect of these drugs. These actions, as well as the potential prescription of steroid therapy and change in the underlying disease treatment approaches, are an important factor in reducing the incidence of respiratory failure in the population.


Author(s):  
Yu. L. Mizernitskiy ◽  
N. S. Lev

Interstitial lung diseases refer to a large group of diseases with a severe course and unfavorable prognosis, since the most forms of these diseases cause irreversible fibrosis of the lung tissue and severe respiratory failure. Lung transplantation remains the only way to save the patient’s.The article highlights the current state of the problem, achievements and prospects in the study, diagnosis and approaches to the treatment of interstitial lung diseases in children. The authors emphasize that this direction is one of the most relevant in pediatric pulmonology and clinical medicine in general.


Author(s):  
N Buda ◽  
M Piskunowicz ◽  
M Porzezińska ◽  
W Kosiak ◽  
Z Zdrojewski

2018 ◽  
Vol 1 (1) ◽  
pp. 25-29
Author(s):  
Mirgolib RAКHIMOV ◽  
◽  
Nematilla ARALOV ◽  
Shukhrat Ziyadullaev

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