scholarly journals Src-family Protein Tyrosine Kinases: A promising target for treating Cardiovascular Diseases

2021 ◽  
Vol 18 (5) ◽  
pp. 1216-1224
Author(s):  
Yuhong Zhai ◽  
Jun Yang ◽  
Jing Zhang ◽  
Jian Yang ◽  
Qi Li ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Tyrosine Kinases ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Promising Target ◽  
Family Protein

scholarly journals Src-family protein tyrosine kinases: A promising target for treating chronic pain

2020 ◽  
Vol 125 ◽  
pp. 110017 ◽  
Author(s):  
Meng-Meng Ge ◽  
Ya-Qun Zhou ◽  
Xue-Bi Tian ◽  
Anne Manyande ◽  
Yu-Ke Tian ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Tyrosine Kinases ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Promising Target ◽  
Family Protein

scholarly journals Differential association of cellular proteins with family protein-tyrosine kinases.

1991 ◽  
Vol 266 (10) ◽  
pp. 6462-6466 ◽  
Author(s):  
O Sartor ◽  
J H Sameshima ◽  
K C Robbins
Keyword(s):  
Tyrosine Kinases ◽  
Protein Tyrosine Kinases ◽  
Differential Association ◽  
Cellular Proteins ◽  
Protein Tyrosine ◽  
Family Protein

Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases

1992 ◽  
Vol 12 (5) ◽  
pp. 2315-2321
Author(s):  
M A Campbell ◽  
B M Sefton
Keyword(s):  
B Cells ◽  
B Cell ◽  
Tyrosine Kinases ◽  
B Lymphocyte ◽  
Protein Tyrosine Kinases ◽  
Cell Type ◽  
Protein Tyrosine ◽  
Membrane Immunoglobulin ◽  
Family Protein

Treatment of B lymphocytes with antibodies to membrane immunoglobulin (Ig) stimulates protein tyrosine phosphorylation. We have examined the phosphorylation in vitro of proteins associated with membrane Ig. The Src family protein tyrosine kinases p53/56lyn, p59fyn, and p56lck are associated with membrane Ig in spleen B cells and B-cell lines and undergo phosphorylation in vitro. The pattern of expression of Src family protein tyrosine kinases in B cells varied. Our studies suggest that multiple kinases can potentially interact with membrane Ig and that within any one B-cell type, all of the Src family kinases expressed can be found in association with membrane Ig. We also observed that the Ig-associated Ig alpha protein, multiple forms of Ig beta, and proteins of 100 and 25 kDa were tyrosine phosphorylated in vitro. The 100- and 25-kDa proteins remain unidentified.

scholarly journals Involvement of Src Family Protein Tyrosine Kinases in Ca 2+ Sensitization of Coronary Artery Contraction Mediated by a Sphingosylphosphorylcholine-Rho-Kinase Pathway

2002 ◽  
Vol 91 (10) ◽  
pp. 953-960 ◽  
Author(s):  
Fumiaki Nakao ◽  
Sei Kobayashi ◽  
Kimiko Mogami ◽  
Yoichi Mizukami ◽  
Satoshi Shirao ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Tyrosine Kinases ◽  
Rho Kinase ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Family Protein ◽  
Kinase Pathway

scholarly journals Allosteric networks governing regulation and catalysis of Src-family protein tyrosine kinases: Implications for disease-associated kinases

2010 ◽  
Vol 37 (1) ◽  
pp. 93-101 ◽  
Author(s):  
Heung-Chin Cheng ◽  
Timothy M Johnson ◽  
Ryan D Mills ◽  
Yuh-Ping Chong ◽  
Khai-Chew Chan ◽  
...  
Keyword(s):  
Tyrosine Kinases ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Family Protein

Rethinking the Role of Src Family Protein Tyrosine Kinases in the Allergic Response: New Insights on the Functional Coupling of the High Affinity IgE Receptor

2004 ◽  
Vol 30 (2) ◽  
pp. 241-254 ◽  
Author(s):  
Yasuko Furumoto ◽  
Claudia Gonzalez-Espinosa ◽  
Gregorio Gomez ◽  
Martina Kovarova ◽  
Sandra Odom ◽  
...  
Keyword(s):  
Tyrosine Kinases ◽  
Allergic Response ◽  
Protein Tyrosine Kinases ◽  
Functional Coupling ◽  
Ige Receptor ◽  
Protein Tyrosine ◽  
High Affinity ◽  
Family Protein ◽  
High Affinity Ige Receptor

scholarly journals Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases.

1992 ◽  
Vol 12 (5) ◽  
pp. 2315-2321 ◽  
Author(s):  
M A Campbell ◽  
B M Sefton
Keyword(s):  
B Cells ◽  
B Cell ◽  
Tyrosine Kinases ◽  
B Lymphocyte ◽  
Protein Tyrosine Kinases ◽  
Cell Type ◽  
Protein Tyrosine ◽  
Membrane Immunoglobulin ◽  
Family Protein

Treatment of B lymphocytes with antibodies to membrane immunoglobulin (Ig) stimulates protein tyrosine phosphorylation. We have examined the phosphorylation in vitro of proteins associated with membrane Ig. The Src family protein tyrosine kinases p53/56lyn, p59fyn, and p56lck are associated with membrane Ig in spleen B cells and B-cell lines and undergo phosphorylation in vitro. The pattern of expression of Src family protein tyrosine kinases in B cells varied. Our studies suggest that multiple kinases can potentially interact with membrane Ig and that within any one B-cell type, all of the Src family kinases expressed can be found in association with membrane Ig. We also observed that the Ig-associated Ig alpha protein, multiple forms of Ig beta, and proteins of 100 and 25 kDa were tyrosine phosphorylated in vitro. The 100- and 25-kDa proteins remain unidentified.

Interactions between Src family protein tyrosine kinases and PSD-95

2003 ◽  
Vol 45 (6) ◽  
pp. 720-728 ◽  
Author(s):  
Lorraine V. Kalia ◽  
Michael W. Salter
Keyword(s):  
Tyrosine Kinases ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Family Protein
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