scholarly journals The role of neuroradiology in intracerebral haemorrhage

2011 ◽  
Vol 2 (1S) ◽  
pp. 31
Author(s):  
Daniele Prosetti ◽  
Francesca Vannozzi ◽  
Fabio Scazzeri
Keyword(s):  
Case Report ◽  
Intracranial Haemorrhage ◽  
Case Reports ◽  
Cerebral Haemorrhage ◽  
Diagnostic Process ◽  
Digital Subtraction ◽  
Computerised Tomography ◽  
Diagnostic Role

The neuroradiologist plays a fundamental role in evaluating cerebral haemorrhage, from the clinical suspect until the final diagnosis.The neuroradiologist’s role consists not only in highlighting the presence of an haemorrhage, but also in specifying its localization and its nature, and in assessing, together with the neurosurgeon, the adequate treatment.With the aid of some case reports, this article underlines the role of neuroradiologist in the diagnostic process. For each case report discussed, computerised tomography (CT) and digital subtraction angiography (DSA) findings are given, to better highlight the diagnostic role of these techniques in the detection and characterization of intracranial haemorrhage.

scholarly journals The role of neuroradiology in intracerebral haemorrhage

2011 ◽  
Vol 2 (1S) ◽  
pp. 31-37
Author(s):  
Daniele Prosetti ◽  
Francesca Vannozzi ◽  
Fabio Scazzeri
Keyword(s):  
Case Report ◽  
Intracranial Haemorrhage ◽  
Case Reports ◽  
Cerebral Haemorrhage ◽  
Diagnostic Process ◽  
Digital Subtraction ◽  
Computerised Tomography ◽  
Diagnostic Role

The neuroradiologist plays a fundamental role in evaluating cerebral haemorrhage, from the clinical suspect until the final diagnosis.The neuroradiologist’s role consists not only in highlighting the presence of an haemorrhage, but also in specifying its localization and its nature, and in assessing, together with the neurosurgeon, the adequate treatment.With the aid of some case reports, this article underlines the role of neuroradiologist in the diagnostic process. For each case report discussed, computerised tomography (CT) and digital subtraction angiography (DSA) findings are given, to better highlight the diagnostic role of these techniques in the detection and characterization of intracranial haemorrhage.

L'angiografia digitale nello studio dei tumori endocranici

1997 ◽  
Vol 10 (2_suppl) ◽  
pp. 149-150
Author(s):  
G. Fabris ◽  
I. Aprile ◽  
E. Biasizzo ◽  
M.C. De Colle ◽  
A. Lavaroni ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Magnetic Resonance ◽  
Digital Subtraction Angiography ◽  
Digital Subtraction ◽  
Intracranial Tumors ◽  
Diagnostic Role ◽  
Nello Studio

The development of Computed Tomography and Magnetic Resonance has reduced the diagnostic role of Digital Subtraction Angiography (DSA) in the neuroradiological evaluation of intracranial tumors. DSA is currently an important pre-surgical examination, able to offer important information regarding the type and the entity of neoplastic vascularization. Moreover the development of endo-vascular interventional practices (pre-surgical embolization of meningiomas and endo-arterious chemotherapy of gliomas) has widened the applications of angiography.

scholarly journals Potential of Radiolabeled PSMA PET/CT or PET/MRI Diagnostic Procedures in Gliomas/Glioblastomas

2020 ◽  
Vol 13 (2) ◽  
pp. 94-98 ◽  
Author(s):  
Francesco Bertagna ◽  
Domenico Albano ◽  
Elisabetta Cerudelli ◽  
Maria Gazzilli ◽  
Raffaele Giubbini ◽  
...  
Keyword(s):  
Case Reports ◽  
Case Series ◽  
Whole Body ◽  
Cochrane Library ◽  
Whole Body Imaging ◽  
Mri Imaging ◽  
Psma Pet ◽  
Pet Ct ◽  
Diagnostic Role

Background: Radiolabeled prostate-specific membrane antigen PSMA-based PET/CT or PET/MRI is a whole-body imaging technique currently performed for the detection of prostate cancer lesions. PSMA has been also demonstrated to be expressed by the neovasculature of many other solid tumors. Objective: The aim of this review is to evaluate the possible diagnostic role of radiolabeled PSMA PET/CT or PET/MRI in patients with gliomas and glioblastomas, by summarizing the available literature data. Methods: A comprehensive literature search of the PubMed/MEDLINE, Scopus, Embase and Cochrane library databases was conducted to find relevant published articles about the diagnostic performance of radiolabeled PSMA binding agents in PET/CT or PET/MRI imaging of patients with suspected gliomas or glioblastomas. Results: Seven case reports or case series and 3 studies enrolling more than 10 patients showed that gliomas and glioblastoma are PSMA-avid tumors. Conclusion: Radiolabeled PSMA imaging seems to be useful in analyzing glioma/glioblastoma. Further studies enrolling a wider population are needed to clarify the real clinical and diagnostic role of radiolabeled PSMA in this setting and its possible position in the diagnostic flow-chart.

scholarly journals Embryonal tumor with abundant neuropil and true rosettes in the brainstem: case report

2015 ◽  
Vol 16 (3) ◽  
pp. 291-295 ◽  
Author(s):  
Hidetoshi Sato ◽  
Yuzo Terakawa ◽  
Naohiro Tsuyuguchi ◽  
Yuko Kuwae ◽  
Masahiko Ohsawa ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Case Reports ◽  
Subtotal Resection ◽  
Surgical Removal ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Embryonal Tumor

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) is rarely seen in the brainstem, and there are few case reports of brainstem ETANTR in the literature. Accordingly, the characteristics and the role of surgical treatment of this rare entity remain unclear. The authors present a case of brainstem ETANTR involving a 33-month-old boy along with a review of the literature and discuss the role of surgical removal in the treatment of this entity. In the authors’ case, the tumor was surgically treated with subtotal resection, which resulted in improvement of the patient’s preoperative symptoms. Chemotherapy was initiated but did not appear to be effective, radiotherapy was declined, and the boy died 6 months after the operation. Based on their analysis of 10 previously reported cases and their own case, the authors conclude that, with respect to survival, surgery may be beneficial even in cases of ETANTR in the brainstem. They note, however, that further studies with a large number of cases are needed to validate the role of surgical treatment in brainstem ETANTR.

scholarly journals Diagnostic role of whole body bone scintigraphy in atypical skeletal tuberculosis resembling multiple metastases: a case report

2009 ◽  
Vol 3 (1) ◽  
Author(s):  
Majid Assadi ◽  
Iraj Nabipour ◽  
Mohammad Eftekhari ◽  
Abdolali Ebrahimi ◽  
Seyed-Reza Abotorab ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Scintigraphy ◽  
Whole Body ◽  
Skeletal Tuberculosis ◽  
Multiple Metastases ◽  
Diagnostic Role ◽  
Body Bone

scholarly journals Immune checkpoint inhibitor therapy for ACTH-secreting pituitary carcinoma: a new emerging treatment?

2021 ◽  
Vol 184 (1) ◽  
pp. K1-K5 ◽  
Author(s):  
Bastiaan Sol ◽  
Jeroen M K de Filette ◽  
Gil Awada ◽  
Steven Raeymaeckers ◽  
Sandrine Aspeslagh ◽  
...  
Keyword(s):  
Case Report ◽  
Immune Checkpoint ◽  
Checkpoint Inhibitors ◽  
Case Reports ◽  
Pituitary Carcinoma ◽  
Disease Stabilization ◽  
Checkpoint Inhibitor Therapy ◽  
Promising Treatment ◽  
Acth Secreting

Background Pituitary carcinomas are rare but aggressive and require maximally coordinated multimodal therapies. For refractory tumors, unresponsive to temozolomide (TMZ), therapeutic options are limited. Immune checkpoint inhibitors (ICI) may be considered for treatment as illustrated in the present case report. Case We report a patient with ACTH-secreting pituitary carcinoma, progressive after multiple lines of therapy including chemotherapy with TMZ, who demonstrated disease stabilization by a combination of ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) ICI therapy. Discussion Management of pituitary carcinoma beyond TMZ remains ill-defined and relies on case reports. TMZ creates, due to hypermutation, more immunogenic tumors and subsequently potential candidates for ICI therapy. This case report adds support to the possible role of ICI in the treatment of pituitary carcinoma. Conclusion ICI therapy could be a promising treatment option for pituitary carcinoma, considering the mechanisms of TMZ-induced hypermutation with increased immunogenicity, pituitary expression of CTLA-4 and PD-L1, and the frequent occurrence of hypophysitis as a side effect of ICI therapy.

scholarly journals Endoscopic Perspective in Cholangiocarcinoma Diagnostic Process

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
O. Urban ◽  
P. Vanek ◽  
V. Zoundjiekpon ◽  
P. Falt
Keyword(s):  
Clinical Course ◽  
Diagnostic Methods ◽  
Diagnostic Process ◽  
Endoscopic Retrograde ◽  
Cross Sectional ◽  
Laboratory Markers ◽  
Diagnostic Role ◽  
Cross Sectional Imaging ◽  
Biliary Endoscopy

Cholangiocarcinoma is a malignancy arising from the epithelial lining of the intrahepatic or extrahepatic biliary tract. Timely diagnosis is challenging due to its silent clinical course. As reliable laboratory markers are lacking, diagnostic imaging plays a pivotal role. While cross-sectional imaging studies are usually conclusive for intrahepatic lesions, endoscopy plays an essential role in cases of extrahepatic tumors. Rational utilization of different diagnostic methods based on available evidence is needed. This article focuses on the diagnostic role of advanced biliary endoscopy, including endoscopic retrograde cholangiopancreatography, cholangioscopy, endoscopic ultrasonography, and intraductal sonography.

Thrombotic microangiopathy in the course of catastrophic antiphospholipid syndrome successfully treated with eculizumab: case report and systematic review of the literature

Lupus ◽  
2020 ◽  
Vol 29 (6) ◽  
pp. 631-639 ◽  
Author(s):  
Marta Skoczynska ◽  
Mark A Crowther ◽  
Malgorzata Chowaniec ◽  
Monika Ponikowska ◽  
Shruti Chaturvedi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Antiphospholipid Syndrome ◽  
Lupus Erythematosus ◽  
Single Case ◽  
Case Reports ◽  
Review Of The Literature ◽  
Catastrophic Antiphospholipid Syndrome ◽  
Total Remission

Objective The purpose of this study was to characterize the role of eculizumab, a monoclonal antibody against the terminal complement component C5, in patients with catastrophic antiphospholipid syndrome (CAPS). Methods We present a case report of a patient with systemic lupus erythematosus (SLE) and CAPS treated with eculizumab, as well as results of a systematic review of the literature. Results Including our patient, we identified 11 case reports of patients with CAPS treated with eculizumab. All of them had partial or total remission of symptoms. Conclusion Data on eculizumab efficacy in CAPS are promising but are limited to single case reports. More studies are needed to develop evidence-based recommendations for eculizumab use in CAPS.

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