scholarly journals Maternal use of a combination of recreational and antiretroviral drugs (nyaope/whoonga): Case reports of their effects on the respiratory system in infants

2021 ◽  
Vol 27 (3) ◽  
pp. 120
Author(s):  
C P Mashiloane ◽  
P M Jeena ◽  
S A Thula ◽  
S A Singh ◽  
R Masekela
Keyword(s):  
Respiratory System ◽  
Case Reports ◽  
Antiretroviral Drugs

scholarly journals Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review

2014 ◽  
Vol 12 (1) ◽  
pp. 112-119 ◽  
Author(s):  
Natalia Mejias Oliveira ◽  
Felipe Augusto Yamauti Ferreira ◽  
Raquel Yumi Yonamine ◽  
Ethel Zimberg Chehter
Keyword(s):  
Acute Pancreatitis ◽  
Antiretroviral Therapy ◽  
Opportunistic Infections ◽  
Case Reports ◽  
Case Series ◽  
Antiretroviral Drugs ◽  
Pancreatic Involvement ◽  
Frequent Event ◽  
Hiv Seropositive ◽  
Hiv Aids

In HIV-seropositive individuals, the incidence of acute pancreatitis may achieve 40% per year, higher than the 2% found in the general population. Since 1996, when combined antiretroviral therapy, known as HAART (highly active antiretroviral therapy), was introduced, a broad spectrum of harmful factors to the pancreas, such as opportunistic infections and drugs used for chemoprophylaxis, dropped considerably. Nucleotide analogues and metabolic abnormalities, hepatic steatosis and lactic acidosis have emerged as new conditions that can affect the pancreas. To evaluate the role of antiretroviral drugs to treat HIV/AIDS in a scenario of high incidence of acute pancreatitis in this population, a systematic review was performed, including original articles, case reports and case series studies, whose targets were HIV-seropositive patients that developed acute pancreatitis after exposure to any antiretroviral drugs. This association was confirmed after exclusion of other possible etiologies and/or a recurrent episode of acute pancreatitis after re-exposure to the suspected drug. Zidovudine, efavirenz, and protease inhibitors are thought to lead to acute pancreatitis secondary to hyperlipidemia. Nucleotide reverse transcriptase inhibitors, despite being powerful inhibitors of viral replication, induce a wide spectrum of side effects, including myelotoxicity and acute pancreatitis. Didanosine, zalcitabine and stavudine have been reported as causes of acute and chronic pancreatitis. They pose a high risk with cumulative doses. Didanosine with hydroxyurea, alcohol or pentamidine are additional risk factors, leading to lethal pancreatitis, which is not a frequent event. In addition, other drugs used for prophylaxis of AIDS-related opportunistic diseases, such as sulfamethoxazole-trimethoprim and pentamidine, can produce necrotizing pancreatitis. Despite comorbidities that can lead to pancreatic involvement in the HIV/AIDS population, antiretroviral drug-induced pancreatitis should always be considered in the diagnosis of patients with abdominal pain and elevated pancreatic enzymes.

scholarly journals Goldenhar syndrome associated with genital tract abnormality

2019 ◽  
Vol 12 (8) ◽  
pp. e230686
Author(s):  
Jennifer Christina Benjamin
Keyword(s):  
Respiratory System ◽  
Genital Tract ◽  
Reproductive Tract ◽  
Case Reports ◽  
Organ Involvement ◽  
Goldenhar Syndrome ◽  
Numerous Case ◽  
Tract Abnormality ◽  
Vertebral Anomalies ◽  
Urinary Abnormalities

Goldenhar syndrome, also known as oculo-auriculo-vertebral syndrome, has been described since 1952. Traditionally, the syndrome has been described as having eye, ear, facial and vertebral anomalies. However, numerous case reports and reviews have highlighted multi-organ involvement, including cardiovascular, gastrointestinal, respiratory system and urinary abnormalities. We describe a 13 years old who has a reproductive tract abnormality, which has not been reported previously as a finding of Goldenhar syndrome.

scholarly journals SPONTANEOUS PNEUMOTHORAX IN A PATIENT WITH COVID-19

2021 ◽  
Vol 71 (2) ◽  
pp. 721-23
Author(s):  
Syed Turab Fatima Abidi ◽  
Syed Asim Ali Shah ◽  
Aziz Ullah Qadir ◽  
Huma Hussain ◽  
Rifat Yasmin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Respiratory System ◽  
Spontaneous Pneumothorax ◽  
Case Reports ◽  
Term Effect ◽  
Neurological Involvement ◽  
Global Pandemic ◽  
Long Term Effect

The coronavirus disease 2019 (COVID-19) frequently involves the respiratory system causing pneumonia. The disease started in December 2019 and is now a global pandemic. The disease is not limited to the respiratory system and cardiac, cutaneous, and neurological involvement has been reported. Psychiatric features of agitation and delirium have also been described in COVID-19. It is yet to be determined whether this will have any long term effect on the quality of life of these patients. We report a case of delirium in a COVID-19 patient who had also developed spontaneous pneumothorax on the day 15 of illness. Few of such case reports have been reported internationally but to the best of authors' knowledge, no such case has been reported in Pakistan.

Case Reports Link ADHD Stimulants to Skin Eruptions

2011 ◽  
Vol 45 (12) ◽  
pp. 10
Author(s):  
SHERRY BOSCHERT
Keyword(s):  
Case Reports

Bowel ischaemia after endovascular aneurysm repair

VASA ◽  
2018 ◽  
Vol 47 (4) ◽  
pp. 273-277
Author(s):  
Christopher Lowe ◽  
Oussama El Bakbachi ◽  
Damian Kelleher ◽  
Imran Asghar ◽  
Francesco Torella ◽  
...  
Keyword(s):  
Case Reports ◽  
Endovascular Aneurysm Repair ◽  
Artery Occlusion ◽  
Bibliographic Databases ◽  
Bowel Ischaemia ◽  
Prophylactic Measures ◽  
Increased Risk ◽  
Prisma Statement ◽  
Meta Analyses ◽  
Aneurysm Repair

Abstract. The aim of this review was to investigate presentation, aetiology, management, and outcomes of bowel ischaemia following EVAR. We present a case report and searched electronic bibliographic databases to identify published reports of bowel ischaemia following elective infra-renal EVAR not involving hypogastric artery coverage or iliac branch devices. We conducted our review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards. In total, five cohort studies and three case reports were included. These studies detailed some 6,184 infra-renal elective EVARs, without procedure-related occlusion of the hypogastric arteries, performed between 1996 and 2014. Bowel ischaemia in this setting is uncommon with an incidence ranging from 0.5 to 2.8 % and includes a spectrum of severity from mucosal to transmural ischaemia. Due to varying reporting standards, an overall proportion of patients requiring bowel resection could not be ascertained. In the larger series, mortality ranged from 35 to 80 %. Atheroembolization, hypotension, and inferior mesenteric artery occlusion were reported as potential causative factors. Elderly patients and those undergoing prolonged procedures appear at higher risk. Bowel ischaemia is a rare but potentially devastating complication following elective infra-renal EVAR and can occur in the setting of patent mesenteric vessels and hypogastric arteries. Mortality ranges from 35 to 80 %. Further research is required to identify risk factors and establish prophylactic measures in patients that have an increased risk of developing bowel ischaemia after standard infra-renal EVAR.

Cannabis-associated arteritis

VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Cardiovascular Effects ◽  
Causative Factor ◽  
Cannabis Use ◽  
Thromboangiitis Obliterans ◽  
Pathological Features ◽  
Scientific Support ◽  
Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.

Migration of Kirschner Wires after Surgical Stabiliziation of Shoulder Injuries - Four Case Reports

Swiss Surgery ◽  
1999 ◽  
Vol 5 (6) ◽  
pp. 281-287 ◽  
Author(s):  
Schindele ◽  
Hackenbruch ◽  
Sutter ◽  
Schärer ◽  
Leutenegger
Keyword(s):  
Case Reports ◽  
Shoulder Injuries ◽  
Kirschner Wires ◽  
Klinische Symptome

Häufige Frakturen im Bereich der Schulter betreffen je nach Alter die Clavicula oder den proximalen Humerus. Die Indikation zur operativen Stabilisierung ist bei Luxationsfrakturen des lateralen Claviculaendes und bei instabilen und dislozierten Frakturen des proximalen Humerus grosszügig zu stellen. Werden Kirschner-Drähte zur Osteosynthese eingesetzt muss in hohem Masse mit Drahtwanderungen oder Drahtbrüchen gerechnet werden. In mehreren Fällen wird in der Literatur auf diese Komplikation hingewiesen. Anhand von vier Fallbeispielen möchten wir Ursachen und technische Voraussetzungen aufzeigen, die bei dieser operativen Variante zu lebensbedrohlichen Komplikationen durch eine sekundäre Migration führen können. Dies unter Umständen nach Jahren und ohne klinische Symptome. Die Indikation zur Kirschnerdraht-Osteosynthese muss vor allem bei vorliegender Osteoporose zurückhaltend gestellt werden. Regelmässige Kontrollen in der postoperativen Phase werden empfohlen, die Entfernung der Drähte sollte bei konsolidierter Fraktur frühzeitig geplant werden.

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