Amorphous Calcium Phosphate Biomaterials with High Specific Surface Area

2021 ◽  
Author(s):  
◽  
Jana Vecstaudža
Keyword(s):  
Calcium Phosphate ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Amorphous Calcium Phosphate ◽  
Synthesis Method ◽  
High Specific Surface Area ◽  
Structure Stability ◽  
Tissue Replacement ◽  
New Synthesis

The Doctoral Thesis is devoted to synthesis and characterization of amorphous calcium phosphate materials with emphasis on their specific surface area. Ways of optimization of an existing synthesis method are investigated experimentally as well as the development of a new synthesis method for obtaining amorphous calcium phosphate with specific surface area value close to the biological calcium phosphate (>100 m2/g). Amorphous calcium phosphate obtained with the developed method is studied for its structure, stability, thermal properties, furthermore, dense amorphous calcium phosphate bioceramics has been developed using the principles of cold sintering process. The developed biomaterials are intended for bone tissue replacement and regeneration. The Thesis is prepared as a collection of articles. It contains a summary and four publications.

Effect of Synthesis Temperature and Ca/P Ratios on Specific Surface Area of Amorphous Calcium Phosphate

2016 ◽  
Vol 721 ◽  
pp. 172-176 ◽  
Author(s):  
Jana Vecstaudza ◽  
Janis Locs
Keyword(s):  
Calcium Phosphate ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Amorphous Calcium Phosphate ◽  
Calcium Phosphates ◽  
Synthesis Temperature ◽  
Molar Ratios ◽  
Different Temperatures ◽  
Low Crystalline

Amorphous and low crystalline calcium phosphates are prospective candidates for bone implant manufacturing. Amorphous calcium phosphate (ACP) preparation technologies could be improved in terms of specific surface area (SSA) of obtained products. Current study is dedicated to the effect of synthesis temperature and Ca and P molar ratios (Ca/P) on SSA of ACP. Higher SSA can improve bioactivity of biomaterials. ACP was characterized by XRD, FT-IR, SEM and BET N2 adsorption techniques. Spherical nanoparticles (<45 nm in size) were obtained independently of initial Ca/P ratio and synthesis temperature. For the first time comparison of SSA was shown for ACP obtained at different temperatures (0 °C and 20 °C) and Ca/P molar ratios (1.5, 1.67 and 2.2).

Synthesis and Characterization of Porous Mo-W Oxide Nanostructures

2008 ◽  
Vol 8 (12) ◽  
pp. 6445-6450
Author(s):  
F. Paraguay-Delgado ◽  
Y. Verde ◽  
E. Cizniega ◽  
J. A. Lumbreras ◽  
G. Alonso-Nuñez
Keyword(s):  
Electron Microscopy ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Synthesis Method ◽  
Atomic Ratio ◽  
High Specific Surface Area ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Before And After

The present study reports the synthesis method, microstructure characterization, and thermal stability of nanostructured porous mixed oxide (MoO3-WO3) at 550 and 900 °C of annealing. The material was synthesized using a hydrothermal method. The precursor was prepared by aqueous solution using ammonium heptamolibdate and ammonium metatungstate, with an atomic ratio of Mo/W = 1. The pH was adjusted to 5, and then the solution was transferred to a teflon-lined stainless steel autoclave and heated at 200 °C for 48 h. The resultant material was washed using deionized water. The specific surface area, morphology, composition, and microstructure before and after annealing were studied by N2 physisorption, scanning electron microscopy (SEM), analytical transmission electron microscopy (TEM), and X-Ray diffraction (XRD). The initial synthesized materials showed low crystallinity and high specific surface area around (141 m2/g). After thermal annealing the material showed higher crystallinity and diminished its specific surface area drastically.

Synthesis of Amorphous Calcium Phosphate: A Review

2020 ◽  
Vol 850 ◽  
pp. 199-206
Author(s):  
Marika Mosina ◽  
Janis Locs
Keyword(s):  
Calcium Phosphate ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Amorphous Calcium Phosphate ◽  
Molar Ratio ◽  
Synthesis Conditions ◽  
Synthesis Routes

The aim of this study is to summarize various synthesis routes of amorphous calcium phosphate (ACP), focusing on properties, especially Ca/P molar ratio and specific surface area (SSA) of obtained ACP. The effects of synthesis conditions on properties of final products are analysed and discussed.

A new synthesis methodology for SiO2 gel-based nanostructures and their application for elimination of dye pollutants

2020 ◽  
Vol 44 (14) ◽  
pp. 5386-5395
Author(s):  
Mehrdad Farjood ◽  
M. A. Zanjanchi
Keyword(s):  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
High Specific Surface Area ◽  
Dye Pollutants ◽  
New Synthesis ◽  
Synthesis Methodology

A new procedure for preparation of a high specific surface area silica-based nanostructure and its copper-containing active photocatalyst is described.

Biologically inspired, catechol-coordinated, hierarchical organization of raspberry-like calcium phosphate nanospheres with high specific surface area

2018 ◽  
Vol 6 (22) ◽  
pp. 3811-3819 ◽  
Author(s):  
Xiaomin Ma ◽  
Zhe Sun ◽  
Wen Su ◽  
Zeng Yi ◽  
Xinxing Cui ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
High Specific Surface Area ◽  
Hierarchical Organization ◽  
Biologically Inspired

Catechol directs the assembly of mesoporous CaP spheres with a hierarchically reticulated architecture and excellent interconnectivity.

scholarly journals Nanocomposite of CeO2 and High-Coercivity Magnetic Carrier with Large Specific Surface Area

2016 ◽  
Vol 2016 ◽  
pp. 1-13
Author(s):  
Alice Reznickova Mantlikova ◽  
Jiri Plocek ◽  
Barbara Pacakova ◽  
Simona Kubickova ◽  
Ondrej Vik ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Synthesis Method ◽  
High Specific Surface Area ◽  
High Coercivity ◽  
X Ray Diffraction ◽  
X Ray ◽  
Transmission Electron

We succeeded in the preparation of CoFe2O4/CeO2 nanocomposites with very high specific surface area (up to 264 g/m2). First, highly crystalline nanoparticles (NPs) of CoFe2O4 (4.7 nm) were prepared by hydrothermal method in water-alcohol-oleic acid system. The oleate surface coating was subsequently modified by ligand exchange to citrate. Then the NPs were embedded in CeO2 using heterogeneous precipitation from diluted Ce3+ sulphate solution. Dried samples were characterized by Powder X-Ray Diffraction, Energy Dispersive X-Ray Analysis, Scanning and Transmission Electron Microscopy, Mössbauer Spectroscopy, and Brunauer-Emmett-Teller method. Moreover, detailed investigation of magnetic properties of the bare NPs and final composite was carried out. We observed homogeneous embedding of the magnetic NPs into the CeO2 without significant change of their size and magnetic properties. We have thus demonstrated that the proposed synthesis method is suitable for preparation of extremely fine CeO2 nanopowders and their nanocomposites with NPs. The morphology and magnetic nature of the obtained nanocomposites make them a promising candidate for magnetoresponsive catalysis.

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