14. Heart Disease, Heart Surgery, and Death

Keyword(s):  
2004 ◽  
Vol 97 ◽  
pp. S64-S65
Author(s):  
Shuenn-Nan Chiu ◽  
Mei-Hwan Wu ◽  
Ming-Tai Lin ◽  
En-Ting Wu ◽  
Jou-Kou Wang ◽  
...  

1987 ◽  
Vol 59 (12) ◽  
pp. 1216-1218 ◽  
Author(s):  
James W. Grant ◽  
Gerald A. Serwer ◽  
Brenda E. Armstrong ◽  
H.Newland Oldham ◽  
Page A.W. Anderson

2004 ◽  
Vol 132 (suppl. 1) ◽  
pp. 9-13
Author(s):  
Ida Jovanovic ◽  
Vojislav Parezanovic ◽  
Slobodan Ilic ◽  
Djordje Hercog ◽  
Milan Vucicevic ◽  
...  

Cyanotic heart diseases are relatively rare, but they are severe and heterogeneous congenital heart diseases, which require complex surgery. Development of different advanced surgical procedures, such as arterial switch operation (ASO), Fontan and its modifications, Norwood etc. operations, as well as better perioperative care significantly improved survival rate and quality of life of these children. The study group included 308 children treated for cyanotic heart disease in Yugoslavia, in the period January 2000 to July 2004. Some of them (239, 77.6%) were treated at the University Children?s Hospital in Belgrade, and others (69, 22.4%) in different institutions abroad. The age of the operated patients varied between 1 day and 19 years (median 12 months). The patients (pts) were divided into four groups, according to the disease and type of the operation. In the whole group of 308 patients treated due to cyanotic heart disease, there were 232 (75.3%) cases with open heart surgery and 76 (24.7%) with closed procedures. The mortality rate was significantly different between disease/operation groups, and age groups. Average mortality rates differed from 11.8% for palliative procedures to 12.5% for complete corrections. Mortality rate and achieved surgical results in treatment of chil?dren with cyanotic heart diseases were significantly worse than those published by leading cardiac surgery centers in the world. However, there is a clear tendency in introducing new surgical procedures, lowering the age at which the operation is done and decreasing the mortality rates.


Author(s):  
Fatma Ukil Isildak ◽  
Yasemin Yavuz ◽  
Omer Faruk Savluk ◽  
Nihat Cine ◽  
Ufuk Uslu

Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease. Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 months who underwent open-heart surgery (complete correction surgery) with a diagnosis of congenital heart disease at the XXXXXX, between January 1, 2018 - December 31, 2020, were retrospectively included (n = 100). Patient demographics, diagnoses, surgical characteristics, and laboratory findings were recorded and analyzed. Results: Mean age was 13.63 ± 12.05 (range 1.5 - 60) months. eGFR was decreased by more than 50% in 13% of the cases. Compared to the preoperative period, it was found that urea (24th and 48th hour) and creatinine levels increased significantly (p< 0.001, for each), and eGFR decreased significantly in the postoperative period (p< 0.001). Linear regression for eGFR value revealed that longer aortic cross-clamp time (ACCT) was associated with a greater decrease in eGFR (p= 0.046). Other variables included in the model, age (p= 0.128), gender (p= 0.358), RACHS (p= 0.865), body mass index (p= 0.862), prealbumin (p= 0.313), albumin (p= 0.806) and duration of cardiopulmonary bypass (p= 0.921) were found to be non-significant. Conclusion: While there was no relationship between eGFR and preoperative albumin/prealbumin levels in patients who underwent cardiac surgery due to congenital heart disease, longer ACCT was found to be associated with decreased eGFR.


2011 ◽  
Vol 32 (5) ◽  
pp. 578-584 ◽  
Author(s):  
Dong-Man Seo ◽  
Jeong-Jun Park ◽  
Tae-Jin Yun ◽  
Young-Hwue Kim ◽  
Jae-Kon Ko ◽  
...  

Author(s):  
W. Bruce Fye

The development of heart surgery lagged behind operations on other organs. In the 1920s surgeons in Boston and in Europe attempted to open mitral valves that had become obstructed as a complication of rheumatic fever. Most of their patients died, and the operation was abandoned until after World War II. Operations to treat children with specific types of congenital heart disease were developed between 1938 and 1944. But these procedures involved the blood vessels outside the heart rather than structures within it. After the war, surgeons in Boston, Philadelphia, and London showed that it was safe to operate on patients with severe mitral stenosis. Without surgery, these individuals would die of heart failure. Mid-century optimism about the potential of treating patients with heart disease was fueled by the discovery of so-called miracle drugs, such as penicillin and cortisone (for which two Mayo staff members shared the Nobel Prize in 1950).


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