scholarly journals Metastatic Axillary Lymph Node Ratio (LNR) is Prognostically Superior to pN Staging in Patients with Breast Cancer -- Results for 804 Chinese Patients from a Single Institution

2013 ◽  
Vol 14 (9) ◽  
pp. 5219-5223 ◽  
Author(s):  
Xiang-Sheng Xiao ◽  
Hai-Lin Tang ◽  
Xin-Hua Xie ◽  
Lai-Sheng Li ◽  
Ya-Nan Kong ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Chinese Patients ◽  
Axillary Lymph ◽  
Single Institution ◽  
Node Ratio

scholarly journals Age and axillary lymph node ratio in postmenopausal women with T1-T2 node positive breast cancer.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. e11004-e11004
Author(s):  
B. H. Ly ◽  
V. Vinh-Hung ◽  
S. A. Joseph ◽  
N. Coutty ◽  
G. Vlastos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Postmenopausal Women ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Axillary Lymph ◽  
Node Positive ◽  
Node Ratio ◽  
Positive Breast Cancer

scholarly journals Prognostic Value of Metastatic Axillary Lymph Node Ratio for Chinese Breast Cancer Patients

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e61410 ◽  
Author(s):  
San-Gang Wu ◽  
Zhen-Yu He ◽  
Qun Li ◽  
Jia-Yuan Sun ◽  
Feng-Yan Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Axillary Lymph Node ◽  
Prognostic Value ◽  
Lymph Node Ratio ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Node Ratio

P48 Impact of metastatic axillary lymph node ratio on prognostic significance in stage IIIC (pN3) breast cancer

The Breast ◽  
2007 ◽  
Vol 16 ◽  
pp. S26
Author(s):  
H.-K. Lee ◽  
S. Ko ◽  
C. Yoon ◽  
S. Kang ◽  
M. Hur ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Prognostic Significance ◽  
Axillary Lymph ◽  
Stage Iiic ◽  
Node Ratio

Axillary lymph node ratio (LNR) versus pathologic nodal stage (pN) as a prognostic factor in breast cancer: Validation of Vinh-Hung's model in an Indian population.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 1099-1099
Author(s):  
Swati Batra ◽  
Manomoy Ganguly ◽  
Narayanan Kannan ◽  
Rajnish Talwar ◽  
Puneet Takkar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Tertiary Care ◽  
Risk Groups ◽  
Axillary Lymph ◽  
Care Hospital ◽  
Node Ratio

1099 Background: The axillary lymph node ratio (LNR), i.e., the ratio of positive over excised lymph nodes offers potentially improved prognostication, selection for adjuvant therapy and inter-institutional comparability compared to conventional pathological nodal staging (pN). A consensus on appropriate cut-offs however, remains to be achieved. Values of 0.20 and 0.65 to classify patients into low, intermediate and high-risk groups were proposed by Vinh-Hung et al, in the largest study on the subject till date. We perform a validation of the LNR concept for the first time in an independent patient population from the Indian subcontinent. Methods: 225 patients with a median follow-up of 42 months (range: 2 – 246 months) who underwent upfront surgery for breast cancer at a tertiary care hospital in Delhi, India, were retrospectively analysed, using Cox multivariate regression. Results: Using the above cut-off points, 10-year disease-free survival (DFS) rates of 83%, 74% and 28% and adjusted hazard ratios (HR) of 1.19 (95% CI 0.33 to 4.37), 2.21 (95% CI 0.75 to 6.51) and 6.88 (95% CI 1.58 – 29.92; P = 0.01) were obtained for the low-, intermediate- and high-risk groups respectively. The corresponding risks for the pN1, pN2 and pN3 categories were 1.74, 1.74, and 1.35, representing inadequate, even reversed prognostic separation. When both the LNR and pN were included as continuous variables, the nodal ratio remained prognostically significant with an adjusted HR of 12.33 (95% CI 1.1 – 142.5, P = 0.04) in contrast to the number of positive nodes which were not found to be significantly associated with DFS (HR = 0.97, 95% CI 0.9 – 1.1, P = 0.41). Conclusions: The LNR outperformed the pN staging in predicting DFS in our cohort of patients, irrespective of whether it was modeled as a categorical or a continuous variable. Simultaneous analysis with pN only increased its prognostic weight and resulted in exclusion of pN from the multivariate model. Our study thus provides independent external validation of Vinh-Hung’s proposed cut-offs and contributes to the growing body of literature supporting the incorporation of a ratio-based system into breast cancer staging.

scholarly journals Does the Axillary Lymph Node Ratio Have Any Added Prognostic Value over pN Staging for South East Asian Breast Cancer Patients?

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e45809 ◽  
Author(s):  
Nakul Saxena ◽  
Mikael Hartman ◽  
Cheng-Har Yip ◽  
Nirmala Bhoo-Pathy ◽  
Lay Wai Khin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Axillary Lymph Node ◽  
Prognostic Value ◽  
Lymph Node Ratio ◽  
East Asian ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Node Ratio

scholarly journals Prognostic importance of the axillary lymph node ratio in autologous transplantation for high-risk stage II/III breast cancer

2001 ◽  
Vol 27 (8) ◽  
pp. 843-846 ◽  
Author(s):  
B Bolwell ◽  
S Andresen ◽  
B Pohlman ◽  
R Sobecks ◽  
M Goormastic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Autologous Transplantation ◽  
Stage Ii ◽  
Axillary Lymph ◽  
Node Ratio ◽  
Prognostic Importance

scholarly journals Age and Axillary Lymph Node Ratio in Postmenopausal Women with T1‐T2 Node Positive Breast Cancer

2010 ◽  
Vol 15 (10) ◽  
pp. 1050-1062 ◽  
Author(s):  
Vincent Vinh‐Hung ◽  
Sue A. Joseph ◽  
Nadege Coutty ◽  
Bevan Hong Ly ◽  
Georges Vlastos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Postmenopausal Women ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Axillary Lymph ◽  
Node Positive ◽  
Node Ratio ◽  
Positive Breast Cancer

scholarly journals The Prognostic Significance of the Lymph Node Ratio in Axillary Lymph Node Positive Breast Cancer

2011 ◽  
Vol 14 (3) ◽  
pp. 204 ◽  
Author(s):  
Ji-Yoon Kim ◽  
Mi-Ryeong Ryu ◽  
Byung-Ock Choi ◽  
Woo-Chan Park ◽  
Se Jeong Oh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Prognostic Significance ◽  
Axillary Lymph ◽  
Node Positive ◽  
Node Ratio ◽  
Lymph Node Positive ◽  
Positive Breast Cancer

Axillary lymph node ratio and total number of removed lymph nodes: predictors of survival in stage I and II breast cancer

2002 ◽  
Vol 28 (5) ◽  
pp. 481-489 ◽  
Author(s):  
B.C.H van der Wal ◽  
R.M.J.M Butzelaar ◽  
S van der Meij ◽  
M.A Boermeester
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Axillary Lymph Node ◽  
Lymph Node Ratio ◽  
Stage I ◽  
Axillary Lymph ◽  
Node Ratio
Sign in / Sign up

Export Citation Format

Share Document