scholarly journals CYP3A4 Expression in Breast Cancer and its Association with Risk Factors in Mexican Women

2014 ◽  
Vol 15 (8) ◽  
pp. 3805-3809 ◽  
Author(s):  
Esau Floriano-Sanchez ◽  
Noemi Cardenas Rodriguez ◽  
Cindy Bandala ◽  
Elvia Coballase-Urrutia ◽  
Jaime Lopez-Cruz
2012 ◽  
Vol 13 (3) ◽  
pp. 837-846 ◽  
Author(s):  
N. Cardenas-Rodriguez ◽  
E. Lara-Padilla ◽  
C. Bandala ◽  
J. Lopez-Cruz ◽  
C. Uscanga-Carmona ◽  
...  

2000 ◽  
Vol 42 (1) ◽  
Author(s):  
Ana Laura Calderón-Garcidueñas ◽  
Franklin Uriel Parás-Barrientos ◽  
Lilia Cárdenas-Ibarra ◽  
Juan Francisco González-Guerrero ◽  
Enrique Villarreal-Ríos ◽  
...  

2000 ◽  
Vol 34 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Víctor Tovar-Guzmán ◽  
Carlos Hernández-Girón ◽  
Eduardo Lazcano-Ponce ◽  
Isabelle Romieu ◽  
Mauricio Hernández Avila

INTRODUCTION: In Mexico, breast cancer (BC) is one of the main causes of cancer deaths in women, with increasing incidence and mortality in recent years. Therefore, the aim of the study is identify possible risk factors related to BC. METHODS: An epidemiological study of hospital cases of BC and controls with cervical uterine cancer (CUCA) was carried out at eight third level concentration hospitals in Mexico City. The total of 353 incident cases of BC and 630 controls with CUCA were identified among women younger than 75 years who had been residents of the metropolitan area of Mexico City for at least one year. Diagnosis was confirmed histologically in both groups. Variables were analyzed according to biological and statistical plausibility criteria. Univariate, bivariate and multivariate analyses were carried out. Cases and controls were stratified according to the menopausal hormonal status (pre and post menopause). RESULTS: The factors associated with BC were: higher socioeconomic level (OR= 2.77; 95%CI = 1.77 - 4.35); early menarche (OR= 1.32; 95%CI= 0.88 - 2.00); old age at first pregnancy (>31 years: OR= 5.49; 95%CI= 2.16 - 13.98) and a family history of BC (OR= 4.76; 95% CI= 2.10 - 10.79). In contrast, an increase in the duration of the breastfeeding period was a protective factor (>25 months: OR= 0.38; 95%CI= 0.20 - 0.70). CONCLUSIONS: This study contributes to the identification of risk factors for BC described in the international literature, in the population of Mexican women. Breastfeeding appears to play an important role in protecting women from BC. Because of changes in women`s lifestyles, lactation is decreasing in Mexico, and young women tend not to breastfeed or to shorten the duration of lactation.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e22511-e22511
Author(s):  
Fernanda Estefanía Rivera ◽  
Carolina Moreno Licea ◽  
Heriberto Medina Franco ◽  
Karina Sánchez Reyes ◽  
Miguel Varela Cardoso ◽  
...  

e22511 Background: Since 2006 breast cancer has been the main cause of cancer mortality in Mexican women representing 14% of cancer related deaths. In Mexico the incidence and mortality of breast cancer have increased in recent decades and will continue to rise. Despite the vast information media on the prevention of this cancer the diagnosis of between 50 - 70% of cases is carried out in advanced stages probably due to a limited understanding of knowledge and practices of early prevention for breast cancer. Methods: The study universe was 375 Mexican women between 30 - 58 years of age of any socioeconomic level in the open population of Orizaba Veracruz who signed the informed consent form. The socioeconomic level was determined with the index of the Asociación Mexicana de Inteligencia de Mercado y Opinión Pública. The level of knowledge was determined by means of a 10 question survey type test on knowledge and practices of early prevention of breast cancer, based on Norma Oficial Mexicana 041. Period: March-May 2019. Results: Of the 375 women, 145-38.7% corresponded to high, 109-29.1% to medium high, 62-16.5% to medium, 26-6.9% to medium low, 17-4.5% to upper low and 16-4.3% to low socioeconomic levels, respectively. Mean age: 43.17 +7.82. Levels of knowledge were high in 28-7.5%, medium in 211-56.3%, low in 134-35.7% and null in 2-0.5% women respectively. 360-96% received information about prevention of breast cancer . 248-66% knew 1 to 3 risk factors, 101-27% >4 risk factors and 26-7% no risk factors. 338-90% know where to go in case of finding an abnormality in their breasts. 272-72% know the age at which they should perform the first self examination, 76-20% know the age at which they should go with trained health personnel for the exploration of their breasts. 233-62% know the age at which the first mammogram should be performed, 91-24% know the age at which the last mammogram should be performed and 8-22% know the frequency of time that a mammogram should be performed. 247-65% have had the 2 corresponding mammograms in the last 4 years. We recognize that this study may have as a limitation that the sample of patients comprises a specific group of Mexican women, however, due to its heterogeneity, its demographic characteristics could be applicable to Mexico and Latin America. Conclusions: Knowledge of the prevention of breast cancer is medium observing a direct relationship between the socioeconomic level and the level of knowledge. Effective communication between health professionals and women must take into account the socioeconomic level of patients in order to achieve a greater understanding of it and potentially reduce the incidence and mortality rate of breast cancer. It is important not to stop emphasizing the importance of continuing medical education and patient education programs for the early detection of breast cancer by patients and first contact physicians as well as primary and secondary prevention strategies which are vitally important in developing countries.


2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Alexandra Estela Soto‐Piña ◽  
Elías Cardoso‐Peña ◽  
Jose Jesús Garduño‐García ◽  
Ángel Gómez‐Villanueva ◽  
Emilio López‐Chávez

2019 ◽  
Author(s):  
Ângela Gabrielly Quirino Freitas ◽  
Mathias Weller

2018 ◽  
Vol 35 (2) ◽  
pp. 177-183
Author(s):  
정지혜 ◽  
여미진 ◽  
박애령 ◽  
황보신이 ◽  
나현오 ◽  
...  

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