scholarly journals High correlation between skin color based on CIELAB color space, epidermal melanocyte ratio, and melanocyte melanin content

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4815 ◽  
Author(s):  
Wen-Shyan Huang ◽  
Yi-Wen Wang ◽  
Kun-Che Hung ◽  
Pai-Shan Hsieh ◽  
Keng-Yen Fu ◽  
...  
Keyword(s):  
Skin Color ◽  
Linear Regression Analysis ◽  
Color Measurement ◽  
Melanin Content ◽  
Skin Substitutes ◽  
Color Match ◽  
Strong Negative Correlation ◽  
Donor Skin ◽  
Epidermal Melanocyte ◽  
Cielab Color

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve a desired color match. Determining the correlations with the desired skin color measurement based on CIELAB color, epidermal melanocyte numbers, and melanin content of individual melanocytes is critical for clinical application. Method Fifteen foreskin samples from Asian young adults were analyzed for skin color, melanocyte ratio (melanocyte proportion in the epidermis), and melanin concentration. Furthermore, an equation was developed based on CIELAB color with melanocyte ratio, melanin concentration, and the product of melanocyte ratio and melanin concentration. The equation was validated by seeding different ratios of keratinocytes and melanocytes in tissue-engineered skin substitutes, and the degree of fitness in expected skin color was confirmed. Results Linear regression analysis revealed a significant strong negative correlation (r =  − 0.847, R2 = 0.717) between CIELAB L* value and the product of the epidermal melanocyte ratio and cell-based melanin concentration. Furthermore, the results showed that an optimal skin color match was achieved by the formula. Discussion We found that L* value was correlated with the value obtained from multiplying the epidermal melanocyte ratio (R) and melanin content (M) and that this correlation was more significant than either L* vs M or L* vs R. This suggests that more accurate prediction of skin color can be achieved by considering both R and M. Therefore, precise skin color match in treating vitiligo or burn patients would be potentially achievable based on extensive collection of skin data from people of Asian descent.

scholarly journals Deceased donor skin allograft banking: Response and utilization

2010 ◽  
Vol 43 (S 01) ◽  
pp. S114-S120
Author(s):  
Madhuri A. Gore ◽  
Anuradha S. De
Keyword(s):  
Burn Injury ◽  
Deceased Donor ◽  
Indian Society ◽  
Skin Substitutes ◽  
Skin Allograft ◽  
Medical College ◽  
Skin Allografts ◽  
Donor Skin ◽  
Life Saving ◽  
Feasible Option

ABSTRACT Background: In the absence of xenograft and biosynthetic skin substitutes, deceased donor skin allografts is a feasible option for saving life of patient with extensive burn injury in our country. Aims: The first deceased donor skin allograft bank in India became functional at Lokmanya Tilak Municipal (LTM) medical college and hospital on 24th April 2000. The response of Indian society to this new concept of skin donation after death and the pattern of utilization of banked allografts from 2000 to 2010 has been presented in this study. Settings and Design: This allograft skin bank was established by the department of surgery. The departments of surgery and microbiology share the responsibility of smooth functioning of the bank. Materials and Methods: The response in terms of number of donations and the profile of donors was analyzed from records. Pattern and outcome of allograft utilization was studied from specially designed forms. Results: During these ten years, 262 deceased donor skin allograft donations were received. The response showed significant improvement after counselling was extended to the community. Majority of the donors were above 70 years of age and procurement was done at home for most. Skin allografts from 249 donors were used for 165 patients in ten years. The outcome was encouraging with seven deaths in 151 recipients with burn injuries. Conclusions: Our experience shows that the Indian society is ready to accept the concept of skin donation after death. Use of skin allografts is life saving for large burns. We need to prepare guidelines for the establishment of more skin banks in the country.

scholarly journals Effectiveness of Combination of Dentin and Enamel Layers on the Masking Ability of Porcelain

2015 ◽  
Vol 26 (6) ◽  
pp. 654-659 ◽  
Author(s):  
Noéli Boscato ◽  
Fernando Gabriel Hauschild ◽  
Marina da Rosa Kaizer ◽  
Rafael Ratto de Moraes
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Color Variation ◽  
Color Coordinates ◽  
Dentin Thickness ◽  
Cielab Color

This study evaluated the masking ability of different porcelain thicknesses and combination of enamel and/or dentin porcelain layers over simulated background dental substrates with higher (A2) and lower (C4) color values. Combination of the enamel (E) and dentin (D) monolayer porcelain disks with different thicknesses (0.5 mm, 0.8 mm, and 1 mm) resulted in the following bilayer groups (n=10): D1E1, D1E0.8; D1E0.5; D0.8E0.8; D0.8E0.5, and D0.5E0.5. CIELAB color coordinates were measured with a spectrophotometer. The translucency parameter of mono and bilayer specimens and the masking ability estimated by color variation (ΔE*ab) of bilayer specimens over simulated dental substrates were evaluated. Linear regression analysis was used to investigate the relationships translucency parameter × ΔE*, translucency parameter × porcelain thickness, and ΔE* × porcelain thickness. Data were analyzed statistically (α= 0.05). Thinner porcelain disks were associated with higher translucency. Porcelain monolayers were considerably more translucent than bilayers (enamel + dentin). Dentin porcelain was less translucent than enamel porcelain with same thickness. ΔE* was always lower when measured over A2 background. Higher ΔE* was observed for the C4 background, indicating poorer masking ability. Increased ΔE* was significantly associated with increased translucency for both backgrounds. Decreased translucency and ΔE* were associated with increased total porcelain thickness or increased dentin thickness for both backgrounds. In conclusion, increased porcelain thickness (particularly increased dentin layer) and increased porcelain opacity resulted in better masking ability of the dental backgrounds.

scholarly journals Association between sociodemographics factors and dietary patterns during pregnancy

2014 ◽  
Vol 27 (2) ◽  
pp. 173-181 ◽  
Author(s):  
Maria Beatriz Trindade De Castro ◽  
Rita Adriana Gomes De Souza ◽  
Ana Amélia Freitas Vilela ◽  
Gilberto Kac
Keyword(s):  
Linear Regression ◽  
Marital Status ◽  
Dietary Patterns ◽  
Skin Color ◽  
Rio De Janeiro ◽  
Linear Regression Analysis ◽  
Demographic Factors ◽  
Postpartum Women ◽  
Negatively Associated ◽  
Socio Demographic Factors

OBJECTIVE: To investigate the association between socio-demographic factors and dietary patterns in pregnancy. METHODS: Cross-sectional study with baseline data from a cohort of 421 postpartum women aged 18 and 45 years resident in Rio de Janeiro, Brazil. Dietary intake was evaluated with a validated food frequency questionnaire at 15 days following delivery, having as time frame the second and third pregnancy trimesters. Dietary patterns were identified using factor analysis for principal components analysis. The association between socio-demographic factors and the identified dietary patterns was assessed with multiple linear regression analysis. RESULTS: Two dietary patterns were identified: i) healthy: fruits; green vegetables; vegetables; fish; roots, corn and potato; milk and dairy and herbal tea mate, and negatively loadings for alcohol and coffee and ii) mixed: rice; bean; flour and pasta; breads; cake and cookies; soda and juice; sugar and sweets; fatty foods; meats; chicken; and eggs. The linear regression showed that the income (β=0.0002; 95%CI: 0.0002-0.0004) and schooling (β=0.0491; 95%CI: 0.0264-0.0718) were positively associated with healthy pattern, and parity (β=-0.1044; 95%CI: -0.1665- -0.0423) and skin color (β=-0.3102; 95%CI: -0.5256- -0.0947) were negatively associated. Skin color (β=0.1647; 95%CI: 0.0378- 0.2916) and marital status (β=0.1065; 95%CI: 0.0062- 0.2067) were positively associated with mixed pattern and income (β=-0.0001; 95%CI:-0.0002- -0.0001) and schooling (β=-0.0281; 95%CI: -0.0417- -0.0146) were negatively associated. CONCLUSION: Socio-demographic factors such as income, schooling, skin color, marital status and parity were associated with dietary patterns in this sample of postpartum women residents in Rio de Janeiro.

scholarly journals HUBUNGAN PERSENTASE SERANGAN HAMA PENGGEREK BUAH KOPI (Hypothenemus hampei Ferr.(Coleoptera: Scolytidae)) dengan DUGAAN KEHILANGAN HASIL di KECAMATAN BETARA TANJUNG JABUNG BARAT

2016 ◽  
Vol 1 (2) ◽  
pp. 85 ◽  
Author(s):  
Hayata Hayata
Keyword(s):  
Skin Color ◽  
Linear Regression Analysis ◽  
Strong Relationship ◽  
Fruit Color ◽  
Survey Method ◽  
Production Loss ◽  
Hypothenemus Hampei ◽  
Green Beans ◽  
The Relationship

AbstractHypothenemus hampei is one of the main causes of the decrease in production and quality of coffee. The fenomena of this damage can be indicted by dwarfing fruit color changing to a reddish yellow, and finally the fall resulted in a decrease in the quantity and quality of production. This production loss was affected by the attack level of coffe pest. Symptoms of coffe pest attack (PBKo) can be identicated by its attacting form where PBKo can destroy both the unripe and ripe coffe. This research aims to know the relationship attacks Percentage the production loss due to the pest attack. Hypothenemus hampei Ferr. (Coleoptera: Scolytidae) in Betara subdistrict of Tanjung Jabung Barat regency. This research has been conducted in July–August 2016. This research using survey method with linear regression analysis i.e. regression between the percentage of attacks and the percentage of production loss. The attack percentage of PBKo pests in the Parit Panglong Betara village range between 8.20 – 17.76%. The percentage highest production loss results on red skin color coffee 7.11% and low on coffee colored skin green beans 3.95%. The percentage of PBKo pest attack had not showed a very strong relationship with the level of production loss. Keywords: Hypothenemus hampei, coffee AbstrakHypothenemus hampei merupakan salah satu penyebab utama penurunan produksi dan mutu kopi. Kerusakan yang ditimbulkannya berupa buah menjadi tidak berkembang, berubah warna menjadi kuning kemerahan dan akhirnya gugur mengakibatkan penurunan jumlah dan mutu hasil. Kehilangan hasil dipengaruhi oleh tingkat serangan hama penggerek buah kopi. Gejala serangan hama penggerek buah kopi (PBKo) dapat diketahui dari bentuk  serangan dimana PBKo dapat menggerek buah kopi yang masih muda sampai dengan yang masak. Penelitian ini bertujuan untuk mengetahui hubungan Persentase serangan dengan dugaan kehilangan hasil akibat serangan hama penggerek buah kopi Hypothenemus hampei Ferr.(Coleoptera:Scolytidae) di Kecamatan Betara Kabupaten Tanjung Jabung Barat. Penelitian dilaksanakan pada bulan Juli–Agustus 2016. Penelitian ini menggunakan metode survei dengan analisis regresi linier yaitu regresi antara persentase serangan dengan persentase kehilangan hasil. Persentase serangan hama PBKo di Desa Parit Panglong Betara berkisar antara 8,20 – 17,76 %. Persentase kehilangan hasil yang tertinggi didapatkan pada kopi yang warna kulit merah 7,11 % dan terendah pada kopi  yang berwarna kulit biji hijau 3,95 %.  Persentase serangan hama PBKo tidak memperlihatkan hubungan yang kuat dengan tingkat kehilangan hasil Kata kunci : Hypothenemus hampei, kopi

scholarly journals Development of an Image Colorimeter for Noncontact Skin Color Measurement and Application to the Dermatological Treatment

2007 ◽  
Vol 127 (10) ◽  
pp. 1749-1755 ◽  
Author(s):  
Makio Akimoto ◽  
Yu Chen ◽  
Michio Miyazaki ◽  
Toyonobu Yamashita ◽  
Michio Miyakawa ◽  
...  
Keyword(s):  
Skin Color ◽  
Color Measurement

scholarly journals Collagenase and Melanogenesis Inhibitory Effects of Perilla Frutescens Pomace Extract and Its Efficacy in Topical Cosmetic Formulations

Cosmetics ◽  
2020 ◽  
Vol 7 (3) ◽  
pp. 69
Author(s):  
Lapatrada Mungmai ◽  
Weeraya Preedalikit ◽  
Komsak Pintha ◽  
Payungsak Tantipaiboonwong ◽  
Nattapol Aunsri
Keyword(s):  
Skin Color ◽  
Radical Scavenging Activity ◽  
Skin Irritation ◽  
Radical Scavenging ◽  
Perilla Frutescens ◽  
Total Phenolic ◽  
Skin Elasticity ◽  
Melanin Content ◽  
Inhibitory Effects ◽  
Collagenase Activity

In previous studies, Perilla frutescens pomace was shown to contain bioactive phenolic compounds and good anti-oxidative activity. However, reports about collagenase activity and melanogenesis inhibitory effects of P. frutescens pomace are limited. This study aimed to evaluate the bioactivity of P. frutescens pomace extract and incorporate the extract into a cosmetic formulation for evaluating its effects on collagenase and melanogenesis inhibition on human skin. The P. frutescens seeds after an oil pressing process were extracted with ethanol (70% v/v) in order to examine the remaining phytochemical compounds, the bioactivity in pomace perilla, and its efficacy as a skincare product. In this study, total phenolic and total flavonoid contents of P. frutescens seed extract (PFSE) were determined using spectrophotometry. The free radical scavenging activity was determined with 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) radicals and 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) ABTS radicals. Additionally, the effects on collagenase activity, melanin content, and alpha-Melanocyte stimulating hormone (α-MSH) on the viability of cultured B16F10 melanoma cells were investigated. Skin irritation and efficacy of PFSE cream for skin elasticity and skin color were also clinically evaluated. The total phenolic content with gallic acid equivalents (GAE) value and total flavonoids content with catechin equivalents (CE) value were, respectively, 92.79 ± 1.19 and 56.02 ± 2.83 mg/g. Furthermore, PFSE significantly inhibited the collagenase activity (p < 0.001) at the concentration of 400 µg/mL (82 ± 3.23%). These results clearly demonstrated the anti-melanogenic effects on B16F10 cells without causing any cytotoxicity or death. Although there was a slight improvement in skin elasticity in the 4th week compared to the previous week, the 4th week melanin content of the skin significantly decreased from the beginning (p < 0.05) without any irritations. In conclusion, PFSE could be cosmetically considered as a key ingredient that effectively lessens the effects of skin aging and skin hyperpigmentation disorders.

Sign in / Sign up

Export Citation Format

Share Document