scholarly journals Relationship Between Serum Total Carbon Dioxide Concentration and Bicarbonate Concentration in Patients Undergoing Peritoneal Dialysis

Cureus ◽  
2021 ◽  
Author(s):  
Keiji Hirai ◽  
Susumu Ookawara ◽  
Momoko Matsuyama ◽  
Taisuke Kitano ◽  
Kiyonori Ito ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Peritoneal Dialysis ◽  
Carbon Dioxide Concentration ◽  
Total Carbon ◽  
Bicarbonate Concentration

scholarly journals Relationship between serum total carbon dioxide concentration and bicarbonate concentration in patients undergoing hemodialysis

2020 ◽  
Vol 39 (4) ◽  
pp. 441-450
Author(s):  
Keiji Hirai ◽  
Susumu Ookawara ◽  
Junki Morino ◽  
Saori Minato ◽  
Shohei Kaneko ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Concentration ◽  
Total Carbon ◽  
Bicarbonate Concentration

scholarly journals Organic Acids Interfere in the Measurement of Carbon Dioxide Concentration by the Kodak Ektachem 700

1992 ◽  
Vol 29 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Nader Rifai ◽  
John Hyde ◽  
Mariet Iosefsohn ◽  
Allen M. Glasgow ◽  
Steven J Soldin
Keyword(s):  
Carbon Dioxide ◽  
Organic Acids ◽  
Carbon Dioxide Concentration ◽  
Total Carbon ◽  
Blood Gas ◽  
Total Plasma ◽  
Bicarbonate Concentration ◽  
Significant Discrepancy ◽  
Maple Syrup ◽  
Urine Disease

A significant discrepancy was noted in our laboratory between the total plasma carbon dioxide concentration measured by the Kodak Ektachem 700 and the bicarbonate concentration derived from the Corning 170 pH/Blood Gas analyser in an 8-day-old patient. The concentration of total carbon dioxide was 18 mmol/L while the derived bicarbonate was 13 mmol/L. The patient was eventually diagnosed as maple syrup urine disease. This finding led us to examine the effect of various organic acids on the measurement of carbon dioxide by the Ektachem 700. Several interfered significantly. Clinicians should be aware that when organic acid concentrations are increased, the Ektachem 700 total carbon dioxide result may be falsely raised.

Acid–base kinetics during hemodialysis using bicarbonate and lactate as dialysate buffer bases based on the H+ mobilization model

2020 ◽  
Vol 43 (10) ◽  
pp. 645-652
Author(s):  
John K Leypoldt ◽  
Mauro Pietribiasi ◽  
Anna Ebinger ◽  
Michael A Kraus ◽  
Allan Collins ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Concentration ◽  
Compartment Model ◽  
Total Carbon ◽  
Bicarbonate Concentration ◽  
Plasma Bicarbonate ◽  
Hemodialysis Treatment ◽  
Daily Hemodialysis ◽  
Acid Generation ◽  
Carbon Dioxide Concentrations

Background: The H+ mobilization model has been recently reported to accurately describe intradialytic kinetics of plasma bicarbonate concentration; however, the ability of this model to predict changing bicarbonate kinetics after altering the hemodialysis treatment prescription is unclear. Methods: We considered the H+ mobilization model as a pseudo-one-compartment model and showed theoretically that it can be used to determine the acid generation (or production) rate for hemodialysis patients at steady state. It was then demonstrated how changes in predialytic, intradialytic, and immediate postdialytic plasma bicarbonate (or total carbon dioxide) concentrations can be calculated after altering the hemodialysis treatment prescription. Results: Example calculations showed that the H+ mobilization model when considered as a pseudo-one-compartment model predicted increases or decreases in plasma total carbon dioxide concentrations throughout the entire treatment when the dialysate bicarbonate concentration is increased or decreased, respectively, during conventional thrice weekly hemodialysis treatments. It was further shown that this model allowed prediction of the change in plasma total carbon dioxide concentration after transfer of patients from conventional thrice weekly to daily hemodialysis using both bicarbonate and lactate as dialysate buffer bases. Conclusion: The H+ mobilization model can predict changes in plasma bicarbonate or total carbon dioxide concentration during hemodialysis after altering the hemodialysis treatment prescription.

Comparison of two analyzers for measurement of plasma total carbon dioxide concentration in horses

2013 ◽  
Vol 74 (8) ◽  
pp. 1091-1102
Author(s):  
Peter D. Constable ◽  
Stacy H. Tinkler ◽  
Laurent. L. Couëtil
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Concentration ◽  
Total Carbon

Effect of sucralfate on total carbon dioxide concentration in horses subjected to a simulated race test

2010 ◽  
Vol 183 (2) ◽  
pp. 191-195 ◽  
Author(s):  
T.J. Caltabilota ◽  
J.G. Milizio ◽  
S. Malone ◽  
J.D. Kenney ◽  
K.H. McKeever
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Concentration ◽  
Total Carbon

Intracellular pH and Bicarbonate Concentration as Determined in Biopsy Samples from the Quadriceps Muscle of Man at Rest

1977 ◽  
Vol 53 (5) ◽  
pp. 459-466
Author(s):  
K. Sahlin ◽  
A. Alvestrand ◽  
J. Bergström ◽  
E. Hultman
Keyword(s):  
Carbon Dioxide ◽  
Intracellular Ph ◽  
Venous Blood ◽  
Chloride Content ◽  
Quadriceps Muscle ◽  
Total Carbon ◽  
Water Volume ◽  
Bicarbonate Concentration ◽  
Cellular Water ◽  
Muscle Biopsies

1. A method for measuring intracellular pH and bicarbonate concentration of human muscle is described. 2. Muscle biopsies from the quadriceps muscle of 13 healthy subjects at rest were analysed for acid-labile carbon dioxide and volume of extra- and intra-cellular water. Extracellular water volume was estimated from the chloride content and intracellular water volume from the potassium content, or alternatively derived from the sample weight. 3. The measured total carbon dioxide content in muscle was 9·84 ± 1·39 mmol/kg. 4. Assuming a normal membrane potential (88 mV) and Pco2 of muscle equal to venous blood, calculated intracellular pH was 7·00 ± 0·06 and intracellular bicarbonate concentration was 10·2 ± 1·2 mmol/l of water.

scholarly journals Acid-base regulation and blood gas transport following exhaustive exercise in an agnathan, the sea lamprey Petromyzon marinus

1991 ◽  
Vol 159 (1) ◽  
pp. 371-385
Author(s):  
B. L. Tufts
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Transport ◽  
Petromyzon Marinus ◽  
Carbon Dioxide Concentration ◽  
Exhaustive Exercise ◽  
Total Carbon ◽  
Acid Base ◽  
Carbon Dioxide Transport ◽  
Arterial Blood

Exhaustive exercise in cannulated sea lampreys, Petromyzon marinus, resulted in a marked extracellular acidosis in the arterial blood which had both a respiratory and a metabolic component. Blood CO2 tension (PCO2) returned to control levels within an hour after exercise, but the metabolic acidosis had a somewhat longer time course and the extracellular pH (pHe) did not fully recover until the 4 h recovery sample. The magnitude and duration of the changes in both the plasma lactate concentration and the concentration of metabolic protons were very similar and the maximal proton deficit after exercise was, therefore, only 1.5 mequiv l-1. In contrast to the changes in pHe, there were no significant changes in the erythrocyte pH (pHi) following the exercise period. The regulation of pHi was apparently not adrenergically mediated, however, since addition of catecholamines to lamprey blood in vitro had no significant effect on pHi. In addition, the period of exhaustive exercise in vivo was not associated with any significant changes in the mean cellular hemoglobin concentration. The total carbon dioxide concentration in the arterial whole blood and true plasma were both significantly reduced after exercise, but the total carbon dioxide concentration within the erythrocytes was transiently increased. Finally, there was a marked decrease in the arterial PO2 immediately after exercise, which was associated with a significant reduction in the amount of oxygen bound to hemoglobin; however, within 30 min, these values had both returned to normal. The maintenance of pHi presumably contributes to the regulation of oxygen transport in lampreys and it may be particularly important during the brief period immediately after exercise when oxygen transport is clearly compromised. Although several studies have provided evidence that chloride/bicarbonate exchange limitations may exist in agnathan blood in vitro, the present results demonstrate that the characteristics of carbon dioxide transport and acid-base regulation after exercise in P. marinus are not markedly different from those in other lower vertebrates.

scholarly journals The Determination of Total Carbon Dioxide in Water

1960 ◽  
Vol 37 (3) ◽  
pp. 444-460
Author(s):  
T. R. MILBURN ◽  
L. C. BEADLE
Keyword(s):  
Carbon Dioxide ◽  
Sodium Hydroxide Solution ◽  
Carbon Dioxide Concentration ◽  
Total Carbon ◽  
Original Sample ◽  
Dissolved Gas ◽  
Hydroxide Solution ◽  
Extraction Apparatus ◽  
Before And After

1. The method described involves extraction of the dissolved gas from an acidified sample in a modified van Slyke apparatus, and measurement of the electrical resistance of a standard sodium hydroxide solution before and after equilibration with the extracted gas. 2. The original sample must be not less than about 30 ml. for which a 10 ml. sample is drawn into the extraction apparatus. 3. There is a linear relation between the resistance finally measured and the total carbon dioxide content of the original sample up to a maximum determined by the strength of the standard hydroxide solution, which is thus adjusted to the desired range of carbon dioxide concentration, e.g. 0.005N-NaOH for 0-50 mg./l. and 0.02N for 0-200 mg./l. CO2. 4. The method is easily sensitive to 0.3 mg./l. in the range 0-50 mg./l. total carbon dioxide and about 1 mg./l. in the range 0-200 mg./l. With a rigidly standardized procedure increased accuracy was obtained so that replicate determinations on standard solutions in the 0-50 mg./l. range did not differ by more than 0.16 mg./l. 5. Precautions for handling samples containing carbon dioxide in solution prior to determination have been suggested. 6. About 15-20 min. are required for each determination and to Mrs D. E.

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