scholarly journals Oral Carcinoma Cuniculatum: A New Entity in the Clinicopathological Spectrum of Oral Squamous Cell Carcinoma

2017 ◽  
Author(s):  
Uma Vasant Datar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oral Carcinoma ◽  
Carcinoma Cuniculatum

scholarly journals Oral carcinoma cuniculatum: an unacquainted entity with diagnostic challenges—a case report

2022 ◽  
Vol 34 (1) ◽  
Author(s):  
Safaa Baz ◽  
Hatem Wael Amer ◽  
Ali A. Wahed
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Oral Carcinoma ◽  
Diagnostic Features ◽  
Papillary Squamous Cell Carcinoma ◽  
Well Differentiated ◽  
Carcinoma Cuniculatum

Abstract Background Oral carcinoma cuniculatum (OCC) is an unacquainted well-differentiated subtype of oral squamous cell carcinoma, which displays unique clinic-pathological features. Up to date, OCC remains rare with about 75 reported cases, and is frequently missed or even misdiagnosed. Case presentation The aim of the present work was: to report a case of OCC in mandibular gingiva and to highlight its main clinic-pathological diagnostic features: with an exophytic cobble-stone surface and a characteristic endophytic burrowing architecture, as well as to differentiate between it and other closely similar lesions including verrucous carcinoma, papillary squamous cell carcinoma, and well-differentiated conventional oral squamous cell carcinoma. Conclusions An accurate diagnosis of OCC entails awareness of the clinicians and pathologists about its entity, proper knowledge of the diagnostic clinical and histopathological evidence, and the ability to differentiate it from closely similar lesions.

scholarly journals Application of the eighth edition of the American joint committee on cancer staging system for oral carcinoma

2019 ◽  
Vol 72 (5-6) ◽  
pp. 165-170
Author(s):  
Ivana Mijatov ◽  
Sasa Mijatov
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Maxillofacial Surgery ◽  
Staging System ◽  
Nodal Status ◽  
Oral Carcinoma ◽  
Significant Shift ◽  
8Th Edition

Introduction. Oral squamous cell carcinoma is the sixth most common carcinoma in the world. Annually, it accounts for 5% of all newly discovered cancers. The most important prognostic factor is the stage of the disease. The tumor, node, and metastasis staging system has been the cornerstone for clinical classification of oral squamous cell carcinoma. Material and Methods. The study included 65 patients with oral squamous cell carcinoma who underwent surgery at the Clinic of Maxillofacial Surgery of the Clinical Center of Vojvodina in Novi Sad. The tumor, node, and metastasis status was determined according to 7th and 8th edition of the tumor, node, and metastasis classification. Results. Statistical differences between the 7th and 8th edition of tumor, node, and metastasis classification were examined. There was also a change in the nodal status; in 20% of patients there was a transition from N1 to N2, as a result of a more precise definition of nodal status in patients with oral carcinoma. Conclusion. This research has pointed out the significance of tumor size as a predictive factor in oral squamous cell carcinoma, which indicates the importance of its local control (for surgical and radiological treatment). The 8th edition of the tumor, node, and metastasis classification for oral cavity cancers made a significant shift by clearly defining depth of tumor invasion into the tumor status.

scholarly journals Surgical Management of Oral Squamous Cell Carcinoma in Dhaka Dental College Hospital; 31 patients

2018 ◽  
Vol 8 (2) ◽  
pp. 10-13
Author(s):  
Farjana Sultana ◽  
Md Rezaul Karim ◽  
Ismat Ara Haider
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Multidisciplinary Treatment ◽  
Oral Carcinoma ◽  
Whole Body ◽  
Definitive Treatment ◽  
Ablative Surgery

Cancer is a major cause of death throughout the world. Oral cancer is one of the six most frequently occurring cancer.1 In Bangladesh, the number of new cancer cases of whole body per year is about 200000 of which oral cancer is about 20%.2 In our neighboring country India, accounts for thirty-five percent of all newly diagnosed cancers in men. The etiology of oral cancer is well established in most instances with consumption of tobacco in any form and alcohol being the most common etiologic agents. Recently, however, exposure to the human papilloma virus has been implicated in young patients with oral carcinoma. The exact mechanism of carcinogenesis in this setting remains to be elucidated .3 Surgery is the most well established mode of initial definitive treatment for a majority of oral cancers. The factors that affect the choice of treatment are related to the tumor and the patient. Primary site, location, proximity to bone and depth of infiltration are factors, which influence particular surgical approach. Advanced reconstructive techniques that allow free transfer of soft tissue and bone improve the functional and aesthetic outcomes following major ablative surgery .Over the course of the past thirty years there has been improvement in the overall survival of patients with oral carcinoma largely due to the improved understanding of the biology of local progression, early identification and treatment of metastatic lymph nodes in the neck and employment of adjuvant post-operative radiotherapy or chemotherapy. Either the role of surgery in oral cancer has evolved with integration of multidisciplinary treatment approaches employing chemotherapy and radiotherapy sequentially or concurrently .Surgical expertise is required for rehabilitation of functional and aesthetic defects created by initial treatment of cancer. Thus, surgery and services of a surgeon remain central to the management of oral cancer.4 A cross sectional study of 31patients undergoing surgery for the treatment of oral squamous cell carcinoma was carried out at Department of Oral & Maxillofacial Surgery ,Dhaka Dental college & hospital from May 2016 to July2017. Here 31 patients, of them male 13 and female 18 having 31 to 80years age ranges of oral squamous cell carcinoma who underwent surgery and reconstruction were included in this study. All patients were referred to oncologist after surgery. Aim of this study was to assess the status of disease, to provide the patient surgical treatment as a first line therapy, to find out any post-operative complications. Update Dent. Coll. j: 2018; 8 (2): 10-13

scholarly journals An in vivo cytogenetic analysis of human oral squamous cell carcinoma

2015 ◽  
Vol 04 (03) ◽  
pp. 123-126 ◽  
Author(s):  
Abhimanyu Mohanta ◽  
Prafulla K. Mohanty ◽  
Gadadhar Parida
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Early Detection ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cytogenetic Analysis ◽  
Micronucleus Test ◽  
Oral Carcinoma ◽  
Genetic Toxicology

Abstract Background: Oral cancer ranks in the top three of all cancers in India, which accounts for over 30% of all cancers reported in the country. The micronucleus test (MNT) is one of the most widely applied short term tests used in genetic toxicology to evaluate the mutagenicity and carcinogenicity. Aims: The present study aims at an in vivo cytogenetic analysis of human oral squamous cell carcinoma and to assess the applicability of MNT in diagnosing early detection of oral carcinoma. Materials and Methods: Exfoliated scrape smears were collected from the clinically diagnosed 136 patients suffering from oral precancerous and cancerous lesions. The wet fixed smears were stained by adopting Papanicolaou’s staining protocol and counter-stained with Giemsa’s solution. Results: The frequency of micronucleated cells has been observed to be in increasing order with the increase of the age-groups and from control to precancerous to cancerous cases significantly in both sexes. Conclusion: Micronucleus formation in the oral mucosa could be a biomarker of genetic damage and also a potential onco-indicator in the long run of oral carcinogenesis. Therefore, MNT can be applied for the early detection of oral carcinoma in the human being.

scholarly journals Risk factors in oral carcinoma and the relationship between tumor thickness and regional nodal involvement: a pilot study in a semi urban population in New Delhi, India

2017 ◽  
Vol 5 (3) ◽  
pp. 1021
Author(s):  
Sujata Jetley ◽  
Zeeba S. Jairajpuri ◽  
Sama Rizvi
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tumor Thickness ◽  
Oral Carcinoma ◽  
Major Public Health Problem ◽  
Cervical Lymph Nodes ◽  
T Stage

Background: Oral squamous cell carcinoma (OSCC) is a major public health problem worldwide, with approximately 275,000 cases annually and a strong association with risk factors like smoking. It is a subtype of head & neck cancer involving the oral cavity.  The present study evaluated the role of various risk factors in the development of oral carcinoma among our patient population.Methods: A total of 40 cases of oral carcinoma with radical neck dissection were evaluated. Data on the age, personal history and presenting clinical features were analyzed. The depth of the tumor and the maximum tumor thickness were carefully evaluated. Also, pathological T-stage, the presence/absence of vascular and peri-neural infiltration was evaluated in each case. The presence of nodal metastases and the stage of the tumor was assessed. Data was tabulated and correlation of nodal metastasis with tumor thickness, pathological T-stage, vascular invasion, and peri-neural infiltration was evaluated by appropriate statistical analysis method.Results: A total of 40 cases, 82.5% males and 17.5% females, were all smokers with history of consumption of smoking or smokeless or both. Tongue was the most common site of oral carcinoma (37.5%) involvement, histological characterization of all were Squamous cell carcinoma with majority of the patients in pathological stage II. A significant association between the tumor thickness and metastasis was also seen.  Conclusions: The tumor thickness of oral squamous cell carcinoma was found to be an important prognostic indicator for the occurrence of metastases to the regional cervical lymph nodes.

Sign in / Sign up

Export Citation Format

Share Document