Maternal Hydration Therapy Improves the Quantity of Amniotic Fluid and the Pregnancy Outcome in Third-Trimester Isolated Oligohydramnios

2014 ◽  
Vol 33 (5) ◽  
pp. 922-922 ◽  
Author(s):  
Kahraman Ülker
Keyword(s):  
Amniotic Fluid ◽  
Pregnancy Outcome ◽  
Third Trimester ◽  
Hydration Therapy

Maternal Hydration Therapy Improves the Quantity of Amniotic Fluid and the Pregnancy Outcome in Third-Trimester Isolated Oligohydramnios

2012 ◽  
Vol 31 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Tito Silvio Patrelli ◽  
Salvatore Gizzo ◽  
Erich Cosmi ◽  
Maria Giovanna Carpano ◽  
Stefania Di Gangi ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Pregnancy Outcome ◽  
Third Trimester ◽  
Hydration Therapy

scholarly journals Pregnancy outcome in isolated oligohydramnios diagnosed in third trimester

2021 ◽  
Vol 10 (5) ◽  
pp. 1914
Author(s):  
Pratibha Singh ◽  
Vibha Rani Pipal ◽  
Dharmendra Kumar Pipal ◽  
Navdeep Kaur Ghuman ◽  
Garima Yadav ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Amniotic Fluid ◽  
Pregnancy Outcome ◽  
Preterm Delivery ◽  
Neonatal Outcome ◽  
Low Risk ◽  
Control Group ◽  
P Value ◽  
Third Trimester

Background: The aim of this study was to compare the outcomes of pregnancies complicated by isolated oligohydramnios with the low risk pregnancies with normal amniotic fluid volume.Methods: The present study is a retrospective cohort study of singleton pregnancies diagnosed with Isolated oligohydramnios (AFI≤5) in their third trimester (N=35). Pregnancy outcome was compared with a matched control group of low risk pregnancies with amniotic fluid volume >5 (N=30).Results: The overall incidence of Isolated oligohydramnios was 0.7-0.8%. In oligohydramnios group, significant association were found in null-parity (60% vs 23.33%, p-value<0.005), Fetal growth retardation (25.71% vs 0% p-value<0.02), preterm delivery (22.85% vs 3.33%, p-value 0.025), rate of Induction of labor (40% vs 10%) and cesarean rate for non-reassuring fetal heart rate (20% vs 3.33%, p-value<0.001). Likewise, the incidence of low birth weight was (54.28% vs 13.33%, p-value<0.001) and NICU admissions was (20% vs 0%, p-value<0.01), but there was no difference in Apgar score finding. NICU stay was of short duration and all babies discharged in stable condition, there were no stillbirth or early neonatal death in both groups.Conclusions: Isolated oligohydramnios has an adverse influence on pregnancy and neonatal outcome in the form of FGR, preterm delivery, increased rate of Induction and cesarean section. Despite the high incidence of low birth weight and NICU admissions, the overall early neonatal outcome was similar to the other low risk pregnancies.

Comparison of Mean Amniotic Fluid Index in Maternal Oral Hydration Therapy with Routine Hydration in Third Trimester Oligohydramnios

2017 ◽  
Vol 11 (3) ◽  
pp. 257-260
Author(s):  
Alfreed Zafar ◽  
Sehrish Maqsood ◽  
Ammara Niaz ◽  
Shagufta Noor ◽  
Naureen Javed
Keyword(s):  
Amniotic Fluid ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Oral Hydration ◽  
Hydration Therapy

scholarly journals De‐novo abnormal uteroplacental circulation in third trimester: pregnancy outcome and pathological implications

2018 ◽  
Vol 52 (1) ◽  
pp. 60-65 ◽  
Author(s):  
J. Binder ◽  
C. Monaghan ◽  
B. Thilaganathan ◽  
S. Carta ◽  
A. Khalil
Keyword(s):  
Pregnancy Outcome ◽  
De Novo ◽  
Third Trimester ◽  
Trimester Pregnancy

scholarly journals Human Amniotic Fluid Mesenchymal Stem Cells from Second- and Third-Trimester Amniocentesis: Differentiation Potential, Molecular Signature, and Proteome Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Jurate Savickiene ◽  
Grazina Treigyte ◽  
Sandra Baronaite ◽  
Giedre Valiuliene ◽  
Algirdas Kaupinis ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Amniotic Fluid ◽  
Expression Patterns ◽  
Specific Gene ◽  
Specific Cell ◽  
Third Trimester ◽  
Human Amniotic Fluid ◽  
Differentiation Potential

Human amniotic fluid stem cells have become an attractive stem cell source for potential applications in regenerative medicine and tissue engineering. The aim of this study was to characterize amniotic fluid-derived mesenchymal stem cells (AF-MSCs) from second- and third-trimester of gestation. Using two-stage protocol, MSCs were successfully cultured and exhibited typical stem cell morphological, specific cell surface, and pluripotency markers characteristics. AF-MSCs differentiated into adipocytes, osteocytes, chondrocytes, myocytes, and neuronal cells, as determined by morphological changes, cell staining, and RT-qPCR showing the tissue-specific gene presence for differentiated cell lineages. Using SYNAPT G2 High Definition Mass Spectrometry technique approach, we performed for the first time the comparative proteomic analysis between undifferentiated AF-MSCs from late trimester of gestation and differentiated into myogenic, adipogenic, osteogenic, and neurogenic lineages. The analysis of the functional and expression patterns of 250 high abundance proteins selected from more than 1400 demonstrated the similar proteome of cultured and differentiated AF-MSCs but the unique changes in their expression profile during cell differentiation that may help the identification of key markers in differentiated cells. Our results provide evidence that human amniotic fluid of second- and third-trimester contains stem cells with multilineage potential and may be attractive source for clinical applications.

scholarly journals Oral versus intravenous maternal hydration in isolated third trimester oligohydramnios

2020 ◽  
Vol 8 (10) ◽  
pp. 3449
Author(s):  
Humaira Zafar ◽  
Mubashra Naz ◽  
Umber Fatima ◽  
Uzma Shahzad ◽  
Anees Fatima ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
P Value ◽  
Amniotic Fluid Index ◽  
Oral Hydration ◽  
Non Invasive ◽  
Invasive Method ◽  
Intravenous Hydration ◽  
Group A ◽  
Group B ◽  
Hydration Therapy

Background: To study the effect of oral and intravenous maternal hydration in patients with isolated oligohydramnios in terms of mean change in amniotic fluid.Methods: A total number of 38 patients included in the study which fulfill the selection criteria.  Patients were randomly divided in two groups. Amniotic fluid index (AFI) of all patients was measured before the hydration therapy according to the method of Phelan et al.  In maternal oral hydration (Group A), every patient was instructed to drink two liters of water over two hours daily for 1 week. In intravenous hydration (Group B), every woman infused two liters of 0.9% normal saline in two hour daily for 1 week. After 48 hours and 1 week of oral and intravenous hydration, the AFI was reassessed by the same observer. Patients were monitored closely for sign and symptoms of fluid overload. Data was stratified for mean difference in improvement in amniotic fluid index.Results: After oral hydration therapy AFI was 5.926±0.4593 after 48 hours and 8.286±0.6000 after 7 days in Group A. In Group B AFI was 5.784±0.4622 after 48 hours and 7.868±0.2810 after 7 days of intravenous hydration. P value after 48 hours is 0.348 and p=0.014 after 7 days means oral hydration therapy significantly increase amniotic fluid index.Conclusions: Oral maternal hydration significantly increase the amniotic fluid index in patients with isolated oligohydramnios. It is simple, safe and non-invasive method.

scholarly journals Maternal (oral) hydration increases amniotic fluid volume

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Aneela Umber
Keyword(s):  
Specific Gravity ◽  
Amniotic Fluid ◽  
Fluid Volume ◽  
Urine Specific Gravity ◽  
P Value ◽  
Percentage Increase ◽  
Third Trimester ◽  
Amniotic Fluid Index ◽  
Oral Hydration ◽  
Amniotic Fluid Volume

Objective:To determine the effect of maternal (oral) hydration on amniotic fluid volume in patients with third trimester oligohydramnios. Design: Interventional study. Place and Duration of Study: Department of Obs & Gynae Unit III, Sir Ganga Ram Hospital, Lahore from May 2002 to October 2002. Patients and Methods: Twenty five women with third trimester oligohydramnios (AFI ?5.0cm) and twenty five controls with normal amniotic fluid volume (AFI 8-24 cm) were prospectively recruited for this study. Maternal urine specific gravity and amniotic fluid index were determined before and after maternal hydration by asking them to drink 2 L of water in 2-4 hours before repeat amniotic fluid index and recorded on printed proformas. Results: Hydration increased amniotic fluid volume in women with oligohydramnios (mean change in amniotic fluid index 4.3 cm, 95% confidence interval 4.02 to 5.06; P value <0.001); as well as in women with normal fluid volume (mean change in Amniotic fluid index 2.7 cm, 95% confidence interval 2.23 to 3.21; P value <0.01). However, percentage increase in mean AFI was 58.6% in the oligohydramnios group, which was significantly greater (P value <0.05) than the percentage increase of 28.4% in control group. Hydration was associated with decrease in urine specific gravity in both groups. Conclusion: Maternal (oral) hydration increases AFV in women with oligohydramnios as well as in women with normal AFV and may be beneficial in the management of oligohydramnios.

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