scholarly journals Improvement of Left Ventricular Mass Following Balloon Angioplasty of Native Coarctation of the Aorta: Midterm follow-up in Cairo University, Children’s Hospital

2013 ◽  
Vol 3 (4) ◽  
pp. 1271-1284
Author(s):  
Mohammed Farouk
Keyword(s):  
Left Ventricular Mass ◽  
Balloon Angioplasty ◽  
Coarctation Of The Aorta ◽  
Left Ventricular ◽  
Children's Hospital ◽  
Ventricular Mass ◽  
Children’S Hospital

scholarly journals Impact of Transcendental Meditation on Left Ventricular Mass in African American Adolescents

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Vernon A. Barnes ◽  
Gaston K. Kapuku ◽  
Frank A. Treiber
Keyword(s):  
African American ◽  
Left Ventricular Mass ◽  
Ventricular Remodeling ◽  
Transcendental Meditation ◽  
African American Adolescents ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Cardiovascular Morbidity And Mortality ◽  
Before And After

Background. An early sign of ventricular remodeling is increased left ventricular mass (LVM) which over time may lead to left ventricular hypertrophy, the strongest predictor of cardiovascular morbidity and mortality, other than advancing age.Methods. 62 (30 TM; 32 CTL) African American adolescents (age16.2±1.3years) with high normal systolic BP were randomly assigned to either 4-month Transcendental Meditation (TM) or health education control groups. The echocardiographic-derived measure of LVM index (LVMI = LVM/ht2.7) was measured before and after the 4-month TM study and at 4-month followup. 2D-guided M-mode echocardiography using a Hewlett Packard 5500 echosonograph was used to determine LVMI.Results. The TM group exhibited a greater decrease in LVMI at 4-month followup compared to the CTL group (−2.6 versus +0.3 gm/ht2.7,P<0.04). The TM group exhibited a lesser increase in BMI at 4-month follow-up compared to the CTL group (0.2±1.6versus1.1±1.4,P<0.03).Conclusion. These findings indicate that among a group of prehypertensive African American adolescents, 4 months of TM compared to heath education resulted in a significant decrease in LVMI, and these changes were maintained at 4-month follow-up.

Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism

2020 ◽  
Vol 105 (11) ◽  
Author(s):  
Chieh-Kai Chan ◽  
Wei-Shiung Yang ◽  
Yen-Hung Lin ◽  
Kuo-How Huang ◽  
Ching-Chu Lu ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Clinical Outcome ◽  
Left Ventricular Mass ◽  
Primary Aldosteronism ◽  
Clinical Success ◽  
Multivariate Logistic Regression Analysis ◽  
Left Ventricular ◽  
Secondary Outcome ◽  
Ventricular Mass

Abstract Context The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified. Objective We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy. Design and Patients We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index. Results We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV&lt;1600 cm/sec was significantly associated with complete cure of hypertension. In addition, higher preoperative baPWV was associated with renal function decline and less left ventricular mass regression after adrenalectomy in lateralized PA patients during the follow-up period. Conclusions Our study demonstrated that the preoperative severe arterial stiffness was associated with absent complete clinical success in lateralized PA patients after adrenalectomy, and this effect may contribute to cardiorenal injury, which at least partially explains kidney function deterioration and lessened regression of heart mass.

Is the burden of late hypertension and cardiovascular target organ damage in children and adolescents with coarctation of the aorta after early successful repair different to healthy controls?

2020 ◽  
Vol 30 (9) ◽  
pp. 1305-1312
Author(s):  
Ayşe Ağbaş ◽  
Selman Gökalp ◽  
Nur Canpolat ◽  
Salim Çalışkan ◽  
Funda Öztunç
Keyword(s):  
Blood Pressure ◽  
Children And Adolescents ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Coarctation Of The Aorta ◽  
Left Ventricular ◽  
Masked Hypertension ◽  
Ventricular Mass Index ◽  
Ventricular Mass ◽  
Successful Repair

AbstractObjective:Cardiovascular morbidity is high in patients with coarctation of aorta even after successful repair. This study aimed to assess the frequency of late hypertension and the relationship between ambulatory hypertension and cardiovascular target organ damage in children and adolescents after early and successful repair of coarctation of the aorta.Methods:Twenty-five children and adolescents (mean age 13.5 ± 3.43 years) with repaired coarctation of the aorta (median age at repair 4 months, arm–leg gradient <20 mmHg) and 16 healthy controls were included. Office and ambulatory blood pressure, pulse wave velocity, and left ventricular mass index were assessed.Results:Both day- and night-time systolic blood pressure standard deviation score and left ventricular mass index were significantly higher in patients compared to controls (p ≤ 0.001 for all), whereas pulse wave velocity did not differ. The prevalence of masked hypertension, isolated nocturnal hypertension, and left ventricular hypertrophy were 40, 28, and 24%, respectively. Left ventricular mass index was higher in patients with sustained hypertension, masked hypertension, and normotension compared to controls (p < 0.05). In multivariate analysis, higher night-time systolic blood pressure standard deviation score was the only independent predictor of left ventricular mass index.Conclusion:The present study reveals a high prevalence of masked hypertension, isolated nocturnal hypertension, and left ventricular hypertrophy in children and adolescents with coarctation of the aorta even after early and successful repair. Ambulatory blood pressure monitoring should be considered to diagnose hypertension. All coarctation of aorta patients should be followed up lifelong and encouraged to establish a healthy lifestyle starting from childhood.

INDEPENDENT PREDICTORS OF LEFT VENTRICULAR MASS IN SUBJECTS WITH MILD TO MODERATE HYPERTENSION AFTER 6 YEARS OF FOLLOW-UP

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S101-S102
Author(s):  
P. Armario ◽  
T. Casanova ◽  
R. Hernandez-Delrey ◽  
M. Martin-Baranera ◽  
N. Andreu-Valls
Keyword(s):  
Left Ventricular Mass ◽  
Moderate Hypertension ◽  
Left Ventricular ◽  
Ventricular Mass

Pulse pressure is the best predictor of future left ventricular mass and change in left ventricular mass: 10 years of follow-up

2001 ◽  
Vol 19 (11) ◽  
pp. 2047-2054 ◽  
Author(s):  
Jaana M. Jokiniitty ◽  
Silja K. Majahalme ◽  
Mika A. P. Kähönen ◽  
Martti T. Tuomisto ◽  
Väinö M. H. Turjanmaa
Keyword(s):  
Left Ventricular Mass ◽  
Pulse Pressure ◽  
Left Ventricular ◽  
Ventricular Mass

scholarly journals High vitamin K status is prospectively associated with decreased left ventricular mass in women: the Hoorn Study

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Joline W. J. Beulens ◽  
Elisa Dal Canto ◽  
Coen D. A. Stehouwer ◽  
Roger J. M. W. Rennenberg ◽  
Petra J. M. Elders ◽  
...  
Keyword(s):  
Heart Failure ◽  
Left Ventricular Mass ◽  
Vitamin K ◽  
Left Ventricular ◽  
Volume Index ◽  
Left Ventricular Ejection ◽  
Cardiac Structure ◽  
High Vitamin ◽  
Ventricular Mass

Abstract Background Vitamin K is associated with reduced cardiovascular disease risk such as heart failure, possibly by carboxylation of matrix-gla protein (MGP), a potent inhibitor of vascular calcification. The relationship of vitamin K intake or status with cardiac structure and function is largely unknown. Therefore this study aims to investigate the prospective association of vitamin K status and intake with echocardiographic measures. Methods This study included 427 participants from the Hoorn Study, a population-based cohort. Vitamin K status was assessed at baseline by plasma desphospho-uncarboxylated MGP (dp-ucMGP) with higher concentrations reflecting lower vitamin K status. Vitamin K intake was assessed at baseline with a validated food-frequency questionnaire. Echocardiography was performed at baseline and after a mean follow-up time of 7.6, SD=±0.7 years. We used linear regression for the association of vitamin K status and intake with left ventricular ejection fraction (LVEF), left atrial volume index (LAVI) and left ventricular mass index (LVMI), adjusted for potential confounders. Results The mean age was 66.8, SD=±6.1 years (51% were male). A high vitamin K status was prospectively associated with decreased LVMI (change from baseline to follow-up: -5.0, 95% CI: -10.5;0.4 g/m2.7) for the highest quartile compared to the lowest in women (P-interaction sex=0.07). No association was found in men. Vitamin K status was not associated with LVEF or LAVI. Vitamin K intake was not associated with any of the echocardiographic measures. Conclusions This study showed a high vitamin K status being associated with decreased LVMI only in women, while intakes of vitamin K were not associated with any cardiac structure or function measures. These results extend previous findings for a role of vitamin K status to decrease heart failure risk.

scholarly journals Regression of Left Ventricular Mass after Implantation of the Sutureless 3f Enable Aortic Bioprosthesis

2015 ◽  
Vol 42 (2) ◽  
pp. 117-123
Author(s):  
Giovanni Concistrè ◽  
Antonio Miceli ◽  
Federica Marchi ◽  
Francesca Chiaramonti ◽  
Mattia Glauber ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Stenosis ◽  
Aortic Valve Replacement ◽  
Left Ventricular Mass ◽  
Valve Replacement ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Mass ◽  
The Mean

Left ventricular hypertrophy in aortic stenosis is considered a compensatory response for the maintenance of systolic function but a risk factor for cardiac morbidity and death. We investigated the degree of left ventricular mass regression after implantation of the sutureless Medtronic 3f Enable® Aortic Bioprosthesis. We studied 19 patients who, from May 2010 through July 2011, underwent isolated aortic valve replacement with the 3f Enable bioprosthetic valve, with clinical and echocardiographic follow-up at 6 months. The mean age was 77.1 ± 5.1 years (range, 68–86 yr); 14 patients were women (73.7%); and the mean logistic EuroSCORE was 15.4% ± 11.8%. Echocardiography was performed preoperatively, at discharge, and at 6 months' follow-up. The left ventricular mass was calculated by means of the Devereux formula and indexed to body surface area. The left ventricular mass index decreased from 146.1 ± 47.6 g/m2 at baseline to 118.1 ± 39.8 g/m2 at follow-up (P=0.003). The left ventricular ejection fraction did not change significantly. The mean transaortic gradient decreased from 57.3 ± 14.2 mmHg at baseline to 12.3 ± 4.6 mmHg at discharge and 12.2 ± 5.3 mmHg at follow-up (P &lt;0.001), and these decreases were accompanied by substantial clinical improvement. No moderate or severe paravalvular leakage was present at discharge or at follow-up. In isolated aortic stenosis, aortic valve replacement with the 3f Enable bioprosthesis results in significant regression of left ventricular mass at 6 months' follow-up. However, this regression needs to be verified by long-term echocardiographic follow-up.

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