An Evaluation of the Levels of Subclinical Malaria Infection and Haemolysis among Residents of Opobo, Rivers State, Nigeria

Aim: The study was aimed at evaluating the levels of subclinical malaria infection and haemolysis among the residents of Opobo, Rivers State, Nigeria. Study Design: A cross sectional study design was used. The subjects were grouped into males and females and comparisons were made between positive and negative subjects of the same gender and positive subjects of different gender. Place and Duration of Study: The study area was Opobo Town in Opobo/Nkoro Local Government Area of Nigeria. The study was carried out within August 2nd to August 26th, 2019 and a total of 89 apparently healthy subjects were recruited, 35 males and 54 females, aged between 16 – 70 years. Methodology: Malaria parasite identification was done by thick and thin film using Giemsa’s stain, packed cell volume was by microhaematocrit method, plasma haemoglobin concentration and whole blood haemoglobin concentration was determined by cyanmethaemoglobin method. Results: The result revealed a total of 24.72% positivity and 75.28% negativity for malaria parasite infection. Among the males, 17.14% positivity and 82.86% negativity for malaria parasite infection were observed while that of the females was 20.37% positivity and 79.63% negativity. In comparison of the studied parameters made between females infected with malaria parasites and those that were not infected with malaria parasites, there was no statistical significant difference at p<0.05 in plasma haemoglobin and percentage haemolysis. In comparison of the studied parameters between males infected with malaria parasites and those not infected with malaria parasites, there was no statistical significant difference in plasma haemoglobin and percentage haemolysis. On gender based comparison, there was also no statistical significant difference in level haemolysis. Conclusion: The study has revealed a prevalence rate of 24.72% for subclinical malaria infection and the percentage haemolysis of red blood cells in malaria infected subjects residing in Opobo Town compared to subjects without malaria parasite was not statistically significant. Based on gender difference, males were affected more than females, but the level of red blood cell haemolysis was not statistically significant after comparison.

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Prevalence of Malaria Parasite Infection among Pregnant Women Attending Antenatal Clinics in Port Harcourt, Rivers State, Nigeria

International Journal of TROPICAL DISEASE & Health ◽

10.9734/ijtdh/2013/2738 ◽

2014 ◽

Vol 3 (2) ◽

pp. 126-132 ◽

Cited By ~ 3

Author(s):

Michael WOGU

Keyword(s):

Pregnant Women ◽

Malaria Parasite ◽

Parasite Infection ◽

Malaria Parasite Infection ◽

Port Harcourt ◽

Antenatal Clinics ◽

Rivers State

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Prevalence and density of malaria parasitaemia amongst HIV Individuals in Warri, Nigeria

African Health Sciences ◽

10.4314/ahs.v21i2.16 ◽

2021 ◽

Vol 21 (2) ◽

pp. 614-618

Author(s):

Johnson Daniel Jemikalajah ◽

Clement Oliseloke Anie ◽

Felix Oghenemaro Enwa

Keyword(s):

Human Immunodeficiency Virus ◽

Malaria Parasite ◽

Staining Technique ◽

Parasite Infection ◽

Malaria Parasitaemia ◽

Malaria Parasite Infection ◽

Significant Difference ◽

Immunodeficiency Virus ◽

The Mean ◽

The Difference

Background: Malaria parasite has been observed to be a common infection in Human Immunodeficiency virus (HIV), an increase malaria infection in adults. Objective: This experimental study is sets to determine the prevalence and density of malaria parasitaemia in Warri com- munity, South-Southern Nigeria. Methods and Results: A total of 600 participants were screened for Human immunodeficiency virus and malaria parasite using WHO systems two and Geimsa staining technique for thick and thin blood films and absolute parasite counts done respectively. The prevalence rate of 38% and 39% were obtained for malaria parasite infection among HIVSP and HIV/ span>SN respectively. The difference in malaria parasite infection was not statistically significant (P>0.05) between HIVSP and HIVSN. However, the mean parasite density in HIVSP was significant (P<0.05) when compared with HIVSN. The mean parasite densities of 2384 ± 747 and 1883 ± 645 were recorded for HIVSP and HIVSN respectively. The mean par- asite densities of 2385 ± 782 and 2383 ± 717 observed for males and females respectively showed no statistical significant difference (P<0.05). Conclusion: This study has shown a high prevalence of malaria parasite among the HIV infected subjects. Keywords: Density; Malaria; HIV; prevalence; Nigeria.

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Malaria Infection and Efficacy of Antimalarials among Persons Patronizing Drugstores for Malaria Treatment in Port Harcourt

International Journal of TROPICAL DISEASE & Health ◽

10.9734/ijtdh/2020/v41i1630361 ◽

2020 ◽

pp. 15-22

Author(s):

E. L. Augustine–D ’israel ◽

A. E. Abah ◽

E. O. Onosakponome

Keyword(s):

Case Management ◽

Malaria Infection ◽

Drug Efficacy ◽

Diagnostic Techniques ◽

Malaria Treatment ◽

Port Harcourt ◽

Significant Difference ◽

Rivers State ◽

And Control ◽

Effective Case

Background: Monitoring of malaria infection and antimalarial drug efficacy is necessary for effective case management, detection of resistance and control of the disease. Objective: The aim of this study was to assess malaria infection and the efficacy of antimalarials among persons patronizing drugstores for malaria treatment in Port Harcourt and its environs, Rivers State, Nigeria. Materials and Methods: Whole blood was randomly collected from individuals visiting 24 drug stores for malaria treatment in three different locations in Port Harcourt and analysed using both microscopy and rapid diagnostic techniques. Results: The overall prevalence of 22.8% was recorded out of 633 participants for (P. falciparum) malaria. Infection was highest in Mile IV (Rumueme) 30.8% followed by Rumuosi, 23.1% and the least was D/Line area, 14.5% out of 221 participants per location respectively. The incidence of malaria in the study area was significantly different (X2 = 16.69; p = 0.001). There was no significant difference in the intensity of malaria parasite infection in the study areas. Seven types of drugs were purchased to treat perceived malaria. 177 (26.7%) participants purchased coatem, 187 (28.3%) purchased Lonart. The others were Lumartem 133 (20.1%), P.alaxin 83 (12.5%), Amarla by 19 (2.9%) and artesunate by 57 (8.6%). All the antimalarial were purchased by those that tested positive. The most purchased drug was Lonart 11 (34.37%), Lumartem 25 (36.8%) and Malareich 19 (31.3%) in D/Line, Mile IV and Rumuosi cluster areas respectively. There was a significant difference in the antimalarials purchased. Result of Follow up test shows that only 59.6% returned to be tested and they all tested negative. Conclusion: Malaria preponderance was high among studied subjects, ACT was topmost among antimalarials regularly purchased by the individuals. Conformity to the use of ACT could be said to be impressive though not yet 100%. People who are treated for malaria should be encouraged to undergo a test after treatment for effective case management and detection of resistance.

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Host ER stress during malaria parasite infection

EMBO Reports ◽

10.15252/embr.201540792 ◽

2015 ◽

Vol 16 (8) ◽

pp. 883-884 ◽

Cited By ~ 8

Author(s):

Alexis Kaushansky ◽

Stefan HI Kappe

Keyword(s):

Er Stress ◽

Malaria Parasite ◽

Parasite Infection ◽

Malaria Parasite Infection

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MALARIA INFECTION: SPECIATION, PARASITE DENSITY, ABO BLOOD GROUP, AND HAEMOGLOBIN CONCENTRATION AMONGST THE INHABITANTS OF BILLIRI LOCAL GOVERNMENT AREA, GOMBE STATE

FUDMA Journal of Sciences ◽

10.33003/fjs-2021-0501-586 ◽

2021 ◽

Vol 5 (1) ◽

pp. 418-423

Author(s):

Nassai Ishaku ◽

G. Chessed ◽

M. S. Pukuma ◽

F. E. Na'acha ◽

N. H. Kure

Keyword(s):

Blood Group ◽

Parasite Density ◽

Malaria Infection ◽

Haemoglobin Concentration ◽

Plasmodium Species ◽

Abo Blood Group ◽

Sociodemographic Characteristics ◽

Public Servants ◽

Infected Female ◽

Significant Difference

The study determines malaria infection with relation to sociodemographic characteristics, parasite density, plasmodium species, ABO blood group, anaemia, and haemoglobin concentration of the participants in Billiri LGA, Gombe State. Informed consent was obtained, and a template was designed containing sociodemographic characteristics of the participants. 381 blood samples were collected and examined using thin and thick film. Out of which 148(38.8%) were infected. Female had the highest infection 82(55.4%) compared to their male counterparts 66(44.6%), with regards to age, those within the age group 11-15years had the maximum infection 41(27.7%) and the least were those within 0 – 5years 3(2.0%). The employment status revealed; others which include students, housewife, and applicants had 49(33.1%) malaria which is the maximum and the minimum was the public servants 25(16.9%), marital status also showed that singles had the highest prevalence 74(50.0%) and the lowest was the widows 8(5.4%), there was a highly significant difference in the sociodemographic characteristics of the participants, p>0.05. With regards to parasitological indices; ABO blood group depicts, participants with blood group O had the maximum infection 60(40.5%) and the least are those with AB 22(14.9), the predominant Plasmodium species is P. falciparum 148(100%), those with moderate parasite density had the highest infection rate 75(50.7%), and 24(16.2%) from those with high, while haemoglobin concentration shows those that are not anaemic had 38(25.7%) infection, and those with critical were 19(12.8%), p<0.05 in all the parasitological indices which is insignificant statistically. Based on this findings, malaria infection is moderate in the study area

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