scholarly journals Burden of Cancer in Plateau State, Central Nigeria: A 27-Year Report from a Tertiary Hospital-Based Cancer Registry

Author(s):  
Barnabas Mafala Mandong ◽  
Agabus Nanfwang Manasseh ◽  
Dauda Madachi Ayuba ◽  
Silas A. Olugbenga ◽  
Innocent Emmanuel ◽  
...  

Cancer has become an emerging disease in the developing world owing to the control of infectious agents and increase longevity. The global anatomical distribution of cancer differs from developed to developing (or resource limited) countries. This article provides information on hospital based cancer registry in Jos University Teaching Hospital (JUTH), for the past 27 years. This was a descriptive retrospective study of consecutive cases of cancer analyzed at the Histopathology Department of JUTH, Jos, between January 1987 and December 2014. All records of cancer diagnosis were extracted from the departmental cancer registry which was established by the Teaching Hospital in 1987. Cases with confirmed histological diagnosis of cancers were included while those with inadequate biodata (age and sex), and anatomical site were excluded. A total of 6,915 cancer cases were recorded for the period of 1987-2014 comprising of 2891 males and 4024 females; giving an annual prevalence of 256 cases per annum. Top 10 cancers accounted for 74% of all cancers, while top 5 cases accounted for 55.8% of cancers. The most frequent cancers were those of the breast, cervical, prostate, lymphoma and liver cancers. The study showed that the most frequent cancers in JUTH are those of the breast, cervix, prostate, liver and lymphomas in decreasing order respectively. Screening should be encouraged in patients at risk to aid prevention and early detection. Allocation of resources to this end should be emphasized.

Author(s):  
Fahmy W F Hanna ◽  
Sarah Hancock ◽  
Cherian George ◽  
Alexander Clark ◽  
Julius Sim ◽  
...  

Abstract Context Adrenal incidentalomas are increasingly being identified during unrelated imaging. Unlike AI clinical management, data on referral patterns in routine practice are lacking. Objective To identify factors associated with AI referral Design We linked data from imaging reports and outpatient bookings from a large UK teaching hospital. We examined; (i) AI prevalence and (ii) pattern of referral to endocrinology, stratified by age, imaging modality, scan anatomical site, requesting clinical specialty and temporal trends. Patients Utilising key radiology phrases to identify scans reporting potential AI, we identified 4,097 individuals from 479,945 scan reports (2015-19). Main Outcome Measures Prevalence of AI and referral rates Results Overall, AI lesions were identified in 1.2% of scans. They were more prevalent in abdomen CT and MRI scans (3.0% and 0.6%, respectively). Scans performed increased 7.7% year-on-year from 2015-19, with a more pronounced rise in the number with AI lesions (14.7% pa). Only 394/4097 patients (9.6%) had a documented endocrinology referral code within 90 days, with medical (11.8%) more likely to refer than surgical (7.2%) specialties (p<0.001). Despite prevalence increasing with age, older patients were less likely to be referred (p<0.001). Conclusions While overall AI prevalence appeared low, scan numbers are large and rising; the number with identified AI are increasing still further. The poor AI referral rates, even in centres such as ours where dedicated AI multi-disciplinary team meetings and digital management systems are used, highlights the need for new streamlined, clinically-effective systems and processes to appropriately manage the AI workload.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2016 ◽  
Vol 10 (3) ◽  
pp. 138-144
Author(s):  
Ajayi Abraham Dare ◽  
Grace Daniel ◽  
Ari Eunice Samuel ◽  
Winna Folashade ◽  
Jacob Onyawole Rachael

2020 ◽  
Author(s):  
Saidu Yusuf Yakubu

Abstract Objectives: Data was collected to determine the level of preparedness and fears of anaesthesia staff regarding the management of COVID-19 patients in a low resource tertiary hospital in Zaria, Nigeria. Information obtained was used to request for missing equipment from the hospital management and to allay the fears of staff during the COVID-19 pandemic. Results: Data reported was from the survey of consenting anaesthesia staff at the Ahmadu Bello University Teaching Hospital Zaria. Information obtained include age, gender, marital status, professional role, level of preparedness, availability of working materials/equipment, fear of COVID-19, level of stress, stigmatization and the willingness or otherwise to volunteer in the management of COVID-19 patients. All 45 respondents stated that they do not have a life insurance. Forty four (97.8%) lack access to COVID-19 testing while 36 (80%) have not received any training on COVID-19 and the use of personal protective equipment. Twenty eight of 43 staff said that they were not willing or prepared to participate in the management of COVID-19 patients. Data will be useful to other researchers with a similar challenge. Data obtained was deposited at https://dx.doi.org/10.17632/stdmys22gk.1.


2019 ◽  
Vol 2 (4) ◽  
pp. 191-196
Author(s):  
ED Jatau ◽  
OB Toma ◽  
OJ Egesie ◽  
DO Damulak ◽  
Z Ayuba ◽  
...  

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.


2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Rufai Abdu Dachi ◽  
Falmata Grema Mustapha ◽  
Saleh Yuguda ◽  
Modu Baba Kagu ◽  
Ali Adamu Gwaram ◽  
...  

Bone Marrow Aspiration (BMA) cytology is an important diagnostic and monitoring tool where cytological details of the marrow elements are examined using light microscopy. Various hematological diseases are diagnosed and monitored by using BMA. This study aimed at reporting a 3-year BMA experience of Department of Hematology and Blood Transfusion of Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) Bauchi. This was a retrospective study that involved the use of records of the bone marrow aspirates done from January 1st, 2016 to December 31st, 2018. The age, sex, indications for BMA, anatomical site and final bone marrow diagnosis were collated. The data was analyzed using SPSS Version 23.0 software. One hundred and three (103) bone marrow aspirations were performed during the period under review. Two third of the participants were males, with the median age of 40.0 years and a range of 5 months to 92 years. The commonest indication for BMA was recurrent anemia 45.6%, followed by splenomegaly, fever and lymphadenopathy with 11.7% each. While, the commonest diagnosis by BMA was megaloblastic anemia (28.2%). Mixed nutritional deficiency and Bone Marrow (BM) metastasis are the commoner BMA diagnoses with 12.6% each. Recurrent anemia is the commonest indication for BMA and nutritional anemias (megaloblastic and combined nutrients deficiency) are the commonest BMA diagnoses in Bauchi. Proper evaluation of patients by the clinicians before referral is recommended to ensure that only those that really need the procedure are subjected to it.


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