The Effect of Platelet-rich Plasma in Treating Androgenic Alopecia in Female Libyan Patients with Curly Hair

2018 ◽  
Vol 18 (2) ◽  
pp. 1-5
Author(s):  
Amghaiab Iman ◽  
Alballali Fathi ◽  
Omran Bugrein
Keyword(s):  
Platelet Rich Plasma ◽  
Androgenic Alopecia ◽  
Curly Hair

Comparison of efficacy of topical 5% minoxidil alone versus topical 5% minoxidil with autologous Platelet Rich Plasma (PRP) therapy in treatment of androgenetic alopecia: A randomised open label study

2021 ◽  
Vol 7 (2) ◽  
pp. 107-114
Author(s):  
Bela Padhiar ◽  
Sruthy Raveendran
Keyword(s):  
Platelet Rich Plasma ◽  
Androgenetic Alopecia ◽  
Androgenic Alopecia ◽  
Open Label ◽  
Hair Density ◽  
Convenience Sample ◽  
Double Spin ◽  
Autologous Platelet Rich Plasma ◽  
Group B ◽  
Autologous Platelet

Androgenic alopecia (AGA) is a type of progressive hairloss, where there is androgen mediated conversion of susceptible terminal hairs into vellus hairs, in genetically predisposed individuals. To compare efficacy of Topical 5% Minoxidil alone versus Topical 5% Minoxidil with Autologous Platelet Rich Plasma (PRP) therapy in patients with Androgenetic Alopecia.This is aProspective study conducted in Department of Dermatology GMERS Medical College, Gandhinagar, Gujarat. A convenience sample of 62 men in the age group of 20-40 with Grade 2-5 AGA according to Hamilton- Norwood Grading were selected and was divided into 2 groups of 31 each. Presitting digital photographs and dermoscopic photos were taken. Autologous PRP was prepared using 18 ml of patients blood after double spin centrifugation and injected by Nappage technique. Results were assessed at the baseline and at the end of each sitting on the basis of change in hair density, photographic evaluation and patient’s self satisfaction. Highly significant increase in hair density was achieved after 4 months of treatment. At T4 (Fourth Session of treatment) Group B showed higher hair density (42.97± 8.96) as compared to Group A (36.94 ± 11.57) which was statistically significant at P = 0.03Group B showed better improvement as compared to Group A.PRP treatment has a positive therapeutic effect on male Androgenetic alopecia without major side effects.

scholarly journals Experience for using platelet‐rich plasma in the treatment of androgenic alopecia (695.8)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Gulnar Batpenova ◽  
Gulnaz Sadykova ◽  
Tatiyana Kotlyarova
Keyword(s):  
Platelet Rich Plasma ◽  
Androgenic Alopecia

scholarly journals Usefulness of PRP Therapy in Androgenic Alopecia

2021 ◽  
Vol 3 (3) ◽  
pp. 93-95
Author(s):  
Zahed Parvez ◽  
Samina Akter ◽  
Afia Tahsin Shobnom
Keyword(s):  
Blood Vessel ◽  
Platelet Rich Plasma ◽  
Clinical Results ◽  
Positive Outcome ◽  
Vessel Density ◽  
Androgenic Alopecia ◽  
Men And Women ◽  
Keratinocyte Proliferation ◽  
Terminal Hair ◽  
Hair Texture

Alopecia means loss of hair. Primarily there are two types of alopecia. Non-cicatricial alopecia and Cicatricial alopecia. Androgenic alopecia is non cicatricial localized alopecia and displays relatively high rates of occurrence in both men and women. Injections of platelet-rich plasma (PRP) have shown to be a successful regenerative treatment for androgenic alopecia. It is a well-tolerated procedure and easy to perform. The objective clinical results are good. It is safe and non-allergenic. In our institution, more than 300 patients were given PRP and their terminal hair mass, hair texture, anagen/telogen hair ratio, keratinocyte proliferation, blood vessel density, and other factors were assessed. More than 85 percent of patients who underwent PRP treatment, had a very positive outcome.

Platelet-Rich Plasma for Treating Androgenic Alopecia: A Systematic Review

2019 ◽  
Vol 43 (5) ◽  
pp. 1326-1336 ◽  
Author(s):  
Guangyu Mao ◽  
Guohui Zhang ◽  
Weixin Fan
Keyword(s):  
Systematic Review ◽  
Platelet Rich Plasma ◽  
Androgenic Alopecia

Platelet-rich plasma as a therapy for androgenic alopecia: a systematic review and meta-analysis

2020 ◽  
pp. 1-14 ◽  
Author(s):  
Adam G. Evans ◽  
James M. Mwangi ◽  
Rand W. Pope ◽  
Mirjana G. Ivanic ◽  
Mina A. Botros ◽  
...  
Keyword(s):  
Systematic Review ◽  
Platelet Rich Plasma ◽  
Meta Analysis ◽  
Androgenic Alopecia

scholarly journals Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy

2020 ◽  
Vol 21 (8) ◽  
pp. 2702 ◽  
Author(s):  
Pietro Gentile ◽  
Simone Garcovich
Keyword(s):  
Systematic Review ◽  
Hair Loss ◽  
Platelet Rich Plasma ◽  
Adult Stem Cell ◽  
Lower Grade ◽  
Androgenic Alopecia ◽  
Positive Effects ◽  
Cell Based Therapy ◽  
Local Injections ◽  
Meta Analyses

The number of articles evaluating platelet-rich plasma (PRP) efficacy in androgenic alopecia (AGA) have exponentially increased during the last decade. A systematic review on this field was performed by assessing in the selected studies the local injections of PRP compared to any control for AGA. The protocol was developed in accordance with the Preferred Reporting for Items for Systematic Reviews and Meta-Analyses-Protocols (PRISMA-P) guidelines. A multistep search of the PubMed, MEDLINE, Embase, PreMEDLINE, Ebase, CINAHL, PsycINFO, Clinicaltrials.gov, Scopus database, and Cochrane databases was performed to identify studies on hair loss treatment with platelet-rich plasma. Of the 163 articles initially identified, 123 articles focusing on AGA were selected and, consequently, only 12 clinical trials were analyzed. The studies included had to match predetermined criteria according to the PICOS (patients, intervention, comparator, outcomes, and study design) approach. In total, 84% of the studies reported a positive effect of PRP for AGA treatment. Among them, 50% of the studies demonstrated a statistically significant improvement using objective measures and 34% of the studies showed hair density and hair thickness improvement, although no p values or statistical analysis was described. In total, 17% of the studies reported greater improvement in lower-grade AGA, while 8% noted increased improvement in higher-grade AGA. Only 17% of the studies reported that PRP was not effective in treating AGA. The information analyzed highlights the positive effects of PRP on AGA, without major side effects and thus it be may considered as a safe and effective alternative procedure to treat hair loss compared with Minoxidil® and Finasteride®.

Does Estradiol Level in Platelet-Rich Plasma Improve Efficacy of Androgenic Alopecia Treatment?

2020 ◽  
Vol 40 (11) ◽  
pp. NP613-NP618
Author(s):  
Bilsev Ince ◽  
Munur Selcuk Kendir ◽  
Ibrahim Kilinc ◽  
Mustafa Cihat Avunduk ◽  
Mehmet Dadaci ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Androgenic Alopecia ◽  
Hair Density ◽  
Level Of Evidence ◽  
Literature Report ◽  
Male Patients ◽  
The Mean ◽  
Group 2 ◽  
Estrogen Concentration ◽  
Group 1

Abstract Background Although some studies in the literature report that autologous and homologous platelet-rich plasma (PRP) can be employed in the treatment of androgenic alopecia (AGA), no study, to the authors’ knowledge, has examined the estrogen concentration of prepared PRP. Objectives The authors aimed to determine the presence of estrogen in PRP and to investigate the effect of estrogen concentration of PRP on AGA treatment. Methods Between 2017 and 2018, 30 male patients with hair loss complaints were included in this prospective study. Autologous PRP was injected in patients in Group 1. Homologous PRP with high estrogen levels was injected in the patients in Group 2. PRP was injected in both groups 4 times at 0, 1, 3, and 6 months. The obtained photographs were evaluated and hair densities of each patient at controls were calculated. Results The mean estrogen level measured in PRP was statistically significantly higher in Group 2. In both groups, the increase in hair density was observed from the first month, but this increase was statistically significantly higher in all controls in Group 2. In Group 2, there was a statistically significant increase in the 1st and 3rd months compared with the previous control, but there was no difference between the 6th and 12th months and the 3rd month. Conclusions Increased hair density is greater and earlier in the group receiving estrogen-rich PRP than in the group utilizing autologous PRP. The authors think that estrogen-rich PRP may be employed in the treatment of AGA in the presence of an appropriate donor. Level of Evidence: 2

Platelet-Rich Plasma for the Treatment of Androgenic Alopecia: A Systematic Review

2018 ◽  
Vol 34 (06) ◽  
pp. 631-640 ◽  
Author(s):  
Jenny Chen ◽  
Natalie Justicz ◽  
Linda Lee
Keyword(s):  
Systematic Review ◽  
Platelet Rich Plasma ◽  
Case Reports ◽  
Androgenic Alopecia ◽  
Delivery Methods ◽  
Facial Plastic Surgery ◽  
Clinical Criteria ◽  
Facial Plastic ◽  
Application Techniques ◽  
Good Patient Satisfaction

AbstractThe use of platelet-rich plasma (PRP) has become increasingly commonplace in facial plastic surgery for the treatment of androgenic alopecia (AGA). However, this treatment remains novel with a range of application techniques and outcomes described in the literature. Herein, the authors systematically review the existing literature on the use and efficacy of PRP for AGA. Systematic review of PubMed, Embase, and Cochrane databases was performed. Case reports were excluded. Twenty-four papers met inclusion criteria for this study: 8 randomized control trials and 16 prospective cohort studies. Twenty-one studies used clinical criteria to diagnose AGA, while three used confirmatory biopsies. PRP was injected with or without the use of a numbing agent, and most studies performed multiple injections (three or more separated by several weeks). Twenty-one studies reported positive outcomes by objective criteria (88%), while three suggested that there was no clinical improvement, although in two of these studies patients still reported increased satisfaction. There were no complications reported other than transient edema/erythema and pain/headache associated with the procedure. The existing literature suggests that PRP is a low-risk intervention to treat AGA associated with good patient satisfaction and objective improvements in outcomes. Further research is needed to optimize preparation and delivery methods as well as standardize measurements of clinical outcomes.

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