scholarly journals Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer

Author(s):  
Sonali Suchismita Behera ◽  
Seema Suvadarshini ◽  
Truptimayee Chhotaray ◽  
Archita Sahoo ◽  
Subhadarshini Satapathy ◽  
...  

Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoic acid can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Author(s):  
Debesh Kumar Hota ◽  
Debadatta Nayak ◽  
Sitaram Swain ◽  
Dipankar Bhattacharyay

Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Utapa Nayak ◽  
Elora Barik ◽  
Bijan Kumar Patra ◽  
Smruti Ranjan Behera ◽  
Mukundjee Pandey ◽  
...  

Alkanna tinctoria plant extract is traditionally used to heal eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 2-Hydroxy-3-Phenyl-1-4-naphthoquinone can can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Sutapa Nayak ◽  
Elora Barik ◽  
Biren Pattanayak ◽  
Sitaram Swain ◽  
Dipankar Bhattacharyay

Phytochemicals from Coffea arabica plant extract are traditionally used to cure conjunctivitis. It is caused by Haemophilus influenza. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeine and chlorogenic acid can efficiently deactivate the shikimate dehydrogenase enzyme which will result in interruption of the life cycle of the microorganism.


Author(s):  
Upendra Kumar Nayak ◽  
Smruti Ranjan Behera ◽  
Saswati Behera ◽  
Dipankar Bhattacharyay ◽  
Mukundjee Pandey

Phytochemicals from Beet Root (Beta vulgaris) plant extract are traditionally used to cure Diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that caffeic acid can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Diptiprajnya Sahoo ◽  
Chinmayee Naik ◽  
Ashwini Kumar Mahanti ◽  
Mukundjee Pandey ◽  
Gyanranjan Mahalik

Phytochemicals from Boswellia serrata Roxb. ex Colebr plant extract are traditionally used to cure skin disease. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that P-cymene can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Debajani Tripathy ◽  
Chandana Adhikari ◽  
Mukundjee Pandey ◽  
Dipankar Bhattacharayay

Phytochemicals from Bhringaraj plant extract are traditionally used to cure Pneumonia. It is caused by Klebsiella pneumonia. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that glutamic acid can effectively deactivate the dehydrogenase enzyme, thereby interrupting the life cycle of the organism.


Author(s):  
Sonali Parida ◽  
Sutapa Nayak ◽  
Seema Suvadarshini ◽  
G. K. Panigrahi ◽  
Sitaram Swain ◽  
...  

Phytochemicals can be derived from different parts of plants. Different medicinal plants and their phytoextracts have shown anti-microbial action. These medicinal plants play a key role in human health care. Phytochemicals from Alpinia galanga plant extract are traditionally used to cure Peptic Ulcer. The objective of the study is to identify the phytochemical of Alpinia galanga capable of curing Peptic Ulcer. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Alpinia galanga derived Phytochemicals cannot act effectively against Peptic Ulcer caused by Helicobacter pylori.


Author(s):  
Bidyashree Tripathy ◽  
Soumya Jal ◽  
Dipankar Bhattacharyay

Cellulitis is a common and sometimes painful bacterial skin infection. Trigonella foenum-graecum extract is traditionally used to cure diseases like cellulitis. Phytochemicals from Trigonella foenum-graecum plant extract can cure Cellulitis. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cellulitis. Molecular docking method applied using “Biovia Discovery Studio”. “The experiment shows that the phytochemical sarginine, carpaine, choline, gentianine and diosgenin failed to deactivate the UDP-glucose 6-dehydrogenase enzyme of Streptococcus pyogenes for treating Cellulitis.


Author(s):  
Chinmayee Naik ◽  
Krutanjali Rout ◽  
Mukundjee Pandey ◽  
Ipsita Priyadarsini Samal ◽  
Shibani Sahoo ◽  
...  

Phytochemicals from Boswellia serrata Roxb. ex Colebt. plant extract are traditionally used to cure diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.


Author(s):  
Sonali Parida ◽  
Jogesh Kumar Nayak ◽  
Anindita Jena ◽  
Arsia Tabish ◽  
Archita Sahoo ◽  
...  

Phytochemicals from Bixa orellana plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoin acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.


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