scholarly journals A Study of Lesions of Upper Respiratory Tract

Author(s):  
K. Anbukkarasi ◽  
Hemalatha Ganapathy ◽  
J. Thanka

The development of the organ systems are highly regulated in physiological conditions and the development of nose and paranasal sinuses commences in the 3rd week of gestation, when the primordial structures first appear and continues until completion in early adulthood when sinus pneumatization and bony growth have ceased. Their misregulation lead to the development of many cancers and primitive nasal septum Squamous cell carcinoma (SCC) of the upper respiratory tract ranks as the sixth leading cause of cancer worldwide.In the current study, out of 31 cases, maximum cases were found to be moderately differentiated grade amounting to 64.5%, followed by well differentiated grade (22.6%) and poorly differentiated grade (12.9%). The present study also showed that poorly differentiated SCC had higher Ki 67 proliferative index and it could be a useful tool for determining the stages of tumors.  Ki 67 proliferative index study of the tumor helps in better understanding of the tumor behavior so as to provide appropriate treatment and thereby increasing the survival rate of the patient.

2021 ◽  
pp. 106689692110628
Author(s):  
Natalia Georgantzoglou ◽  
Donald Green ◽  
Joel A. Lefferts ◽  
Linda Giannikaki ◽  
Eudoxia Chliara ◽  
...  

Dedifferentiated liposarcoma is a nonlipogenic sarcoma of variable histological grade that frequently arises in association with a well-differentiated liposarcoma. Dedifferentiation occurs in approximately 10% of well-differentiated liposarcomas and is most commonly encountered in the retroperitoneum. Dedifferentiated liposarcoma of the upper respiratory tract is an extremely rare occurrence. Herein, we report a very rare case of low-grade dedifferentiated liposarcoma of the pharynx that presented as a polyp mimicking a benign process clinically and microscopically. We discuss the relevant molecular findings and review the current literature.


Author(s):  
Rhoda Leask ◽  
Johan Steyl

Although nasal masses are uncommon in sheep and may have several causes, including neoplasia and bacterial, fungal and viral infections, these lesions may lead to economic losses resulting from weight loss and even death. It is therefore important to differentiate between various categories of upper respiratory tract obstructions and lower respiratory tract infections. The correct aetiological diagnosis of obstructive masses is essential for appropriate treatment and management to be given or action to be taken. The presentation, clinical signs, treatment and pathology of a case of suspected mycotic rhinitis in a 6-year-old Mutton Merino ewe, are described.


Author(s):  
Sowmya Tumkur Rangaiah ◽  
Vikram Kemmannu Bhat ◽  
Mona Yadav

<p class="abstract"><strong>Background:</strong> Regression of adenoids is assumed to be a physiological phenomenon at puberty. However, it has been found that it can persist well beyond adolescence into early adulthood, cascading a series of after effects in the upper respiratory tract that can cause considerable morbidity leading to public health problems. This study aimed to explore the clinicopathological features of persistent adenoids and their secondary effects on the upper respiratory tract.</p><p class="abstract"><strong>Methods:</strong> This was a prospective controlled study of 100 eligible patients in the age group of 15-60 years presenting with enlarged adenoids confirmed by nasal endoscopy. Equal number of controls without enlarged adenoids was also taken. Both the groups were evaluated for secondary effects like chronic rhinosinusitis, otitis media with effusion, chronic otitis media and Eustachian tube dysfunction. The relationship between adenoid enlargement in adults and secondary effects was analysed statistically.  </p><p class="abstract"><strong>Results:</strong> Seventy-seven patients with persistent adenoids had some or the other secondary effect. Eustachian tube dysfunction was present in 21, otitis media with effusion in 10, chronic otitis media in 29 and chronic rhinosinusitis in 33. In the control group only 46 had secondary effects. The association between the presence of adenoids and secondary effects was statistically significant.</p><p class="abstract"><strong>Conclusions:</strong> Adenoids can persist into early adulthood and majority of them can have secondary effects. Chronic rhinosinusitis was the commonest in this study. Careful evaluation by means of nasal endoscopy is required to identify them. This is crucial for the timely treatment of this condition in order to prevent the associated secondary effects.</p>


1970 ◽  
Vol 3 (2) ◽  
pp. 265-276 ◽  
Author(s):  
Jack D. Clemis ◽  
Eugene L. Derlacki

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