scholarly journals A Case of Small Bowel Intimation with Sepsis

Author(s):  
Sanjana Sontakke ◽  
Sagar Alwadkar ◽  
Mayur Wanjari

Introduction: Sepsis is a life-threatening organ failure that occurs in severely ill patients as a result of a primary infectious cause or subsequent infection of injured tissues. The systemic effects of sepsis have been extensively studied, and evidence of local alterations and repercussions in the intestinal mucosal compartment is gradually characterizing sepsis-related changes in the gut. The current study focuses on sepsis-induced intestinal barrier failure, which includes increased epithelial permeability, which may allow bacterial translocation. The small bowel, commonly known as the small intestine, is roughly 1 inch in diameter and 20 to 30 feet long. It has a lot of folds to help it fit inside the abdominal cavity. The small bowel is connected to the stomach on one end and the big intestine on the other. Patient information: He was 63 years old male admitted to Acharya Vinoba Bhave Rural hospital sawangi meghe Wardha in MICU ward with chief complaints of altering sensorium. Low urine output vomiting, loss of appetite, swelling of the abdomen crampy abdominal pain that comes and goes. The Main Diagnosis, Therapeutic Intervention and Outcomes: A CT scan revealed a thicker transverse colon wall. His flexible sigmoidoscopy revealed “patchy inflammation and an isolated area of severe deep ulceration with nodularity and edema,” according to the report. The patient was given a preliminary diagnosis of "Inflammatory Bowel Disease—likely Crohn's," and was treated with steroids and Patient was done colonoscopy and course of inj. hydrocortisone, inj. Neomol, inj. levipril. Conclusion: In the case of acute small-bowel obstruction, helical CT is a highly sensitive approach for diagnosing or ruling out intestinal ischemia. In patients with significant trauma who are being assessed for sepsis of unknown origin, abdominal computed tomographic scans accurately identify intra-abdominal foci of infection. This patient was diagnosed with small bowel intimation and sepsis.

Radiographics ◽  
2001 ◽  
Vol 21 (2) ◽  
pp. 341-355 ◽  
Author(s):  
Akira Furukawa ◽  
Michio Yamasaki ◽  
Kenji Furuichi ◽  
Kenji Yokoyama ◽  
Tamotsu Nagata ◽  
...  

2019 ◽  
Vol 55 (5) ◽  
pp. 481-495 ◽  
Author(s):  
Toshio Watanabe ◽  
Yasuhiro Fujiwara ◽  
Francis K. L. Chan

AbstractRecent advances in small-bowel endoscopy such as capsule endoscopy have shown that non-steroidal anti-inflammatory drugs (NSAIDs) frequently damage the small intestine, with the prevalence rate of mucosal breaks of around 50% in chronic users. A significant proportion of patients with NSAIDs-induced enteropathy are asymptomatic, but some patients develop symptomatic or complicated ulcers that need therapeutic intervention. Both inhibition of prostaglandins due to the inhibition of cyclooxygenases and mitochondrial dysfunction secondary to the topical effect of NSAIDs play a crucial role in the early process of injury. As a result, the intestinal barrier function is impaired, which allows enterobacteria to invade the mucosa. Gram-negative bacteria and endogenous molecules coordinate to trigger inflammatory cascades via Toll-like receptor 4 to induce excessive expression of cytokines such as tumor necrosis factor-α and to activate NLRP3 inflammasome, a multiprotein complex that processes pro-interleukin-1β into its mature form. Finally, neutrophils accumulate in the mucosa, resulting in intestinal ulceration. Currently, misoprostol is the only drug that has a proven beneficial effect on bleeding small intestinal ulcers induced by NSAIDs or low-dose aspirin, but its protection is insufficient. Therefore, the efficacy of the combination of misoprostol with other drugs, especially those targeting the innate immune system, should be assessed in the next step.


2018 ◽  
Vol 84 (6) ◽  
pp. 204-205
Author(s):  
David J. Hiller ◽  
John H. Gilliam ◽  
Gregory S. Waters
Keyword(s):  

2012 ◽  
Vol 1 (2) ◽  
pp. 123-131
Author(s):  
S Ullal ◽  
KS Joshi ◽  
P Pant

Pancreatitis is one of the commonest pancreatic pathology encountered in day to day clinical practice. Early detection of the entity and its complications can significantly reduce the mortality and morbidity. Various imaging modalities are now available including newer interventional techniques for the diagnosis and therapeutic interventions. For diagnostic purposes, Computed Tomography (CT) has long been regarded as one of the most efficient imaging modalities for evaluation of pancreatitis. This pictoral review is based on Helical CT scans performed in total 50 patients suspicious of having pancreatitis in Kasturba Medical College Hospital, Attavara, Mangalore, India between 2008-2009 and Dhulikhel Hospital, Dhulikhel, Nepal 2010. Various morphological features of both acute and chronic pancreatitis were found on helical CT abdomen. The CT features of acute pancreatitis were focal or diffuse enlargement of pancreas, areas of necrosis, peripancreatic fat strandings, extrapancreatic fluid collections, perinephric fat stranding, perirenal fascial thickening, ascites, pleural effusion, pseudocyst formation etc. The CT features of chronic pancreatitis were focal or diffuse atrophy of the gland, duct dilatation, pancreatic calcifications, ductal calculi etc. Various complications encountered were acute fluid collections, pseudocyst formation, necrosis, pseudoaneurysm, portal vein thrombosis, abscess formation etc. DOI: http://dx.doi.org/10.3126/njms.v1i2.6613 Nepal Journal of Medical Sciences. 2012;1(2): 123-31


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Tahsin Colak ◽  
Tolga Olmez ◽  
Ozgur Turkmenoglu ◽  
Ahmet Dag

Gossypiboma, an infrequent surgical complication, is a mass lesion due to a retained surgical sponge surrounded by foreign body reaction. In this case report, we describe gossypiboma in the abdominal cavity which was detected 14 months after the hysterectomy due to acute abdominal pain. Gossypiboma was diagnosed by computed tomography (CT). The CT findings were a rounded mass with a dense central part and an enhancing wall. In explorative laparotomy, small bowel loops were seen to be perforated due to inflammation of long standing gossypiboma. Jejunal resection with end-to-end anastomosis was performed. The patient was discharged whithout complication. This case was presented to point to retained foreign body (RFB) complications and we believed that the possibility of a retained foreign body should be considered in the differential diagnosis of who had previous surgery and complained of pain, infection, or palpable mass.


2004 ◽  
Vol 50 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Mariano Scaglione ◽  
Stefania Romano ◽  
Fabio Pinto ◽  
Ferdinando Flagiello ◽  
Roberto Farina ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Saptarshi Biswas ◽  
Catherine Price ◽  
Sunil Abrol

Bullet embolism within the gastrointestinal system is extremely rare. Such bullet injuries are infrequently covered in the general literature, but the surgeon should be aware of the phenomenon. Smaller caliber bullets are more common in civilian gunshot wound (GSW) events. These bullets are able to tumble through the gastrointestinal tract and cause perforation of the intestinal lumen which is small enough to be easily missed. Bullets retained in the abdominal cavity should not be dismissed as fixed and should be carefully monitored to ensure that they do not embolize within the bowel and cause occult lesions during their migration. We present a unique case wherein a bullet caused a minute perforation in the small bowel, before migrating to the distal colon, which resulted in late presentation of sepsis secondary to peritonitis.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Ye Chu ◽  
Sheng Wu ◽  
Yuting Qian ◽  
Qi Wang ◽  
Juanjuan Li ◽  
...  

Objectives. The complimentary value of computed tomographic enterography (CTE) and double-balloon enteroscopy (DBE) combined with capsule endoscopy (CE) was evaluated in the diagnosis of obscure gastrointestinal bleeding (OGIB).Methods. Patients who received CE examinations at Ruijin Hospital between July 2007 and July 2014 with the indication of OGIB were identified, and those who also underwent DBE and/or CTE were included. Their clinical information was retrieved, and results from each test were compared with findings from the other two examinations.Results. The overall diagnostic yield of CE was comparable with DBE (73.9% versus 60.9%) but was significantly higher than the yield of CTE (87% versus 25%,p<0.001). The diagnostic yield of angiodysplasia at CE was significantly higher than CTE (73% versus 8%,p<0.001) and DBE (39.1% versus 17.4%,p=0.013), while no significant difference was found between the three approaches for small bowel tumors. DBE and CTE identified small bowel diseases undetected or undetermined by CE. Conversely, CE improved diagnosis in the cases with negative CTE and DBE, and findings at initial CE directed further diagnosis made by DBE.Conclusions. Combination of the three diagnostic platforms provides complementary value in the diagnosis of OGIB.


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