Utility of an unitary-shredding method to evaluate the conditions and selection of constructional features during grinding

In order to evaluate and improve the efficiency of the process of grinding, various investigations are conducted, based on the relevant research methodology. One of them is the method in which the crushed sample is subjected to single stroke loads. On this basis, the influence of the geometric features of the chipper system and the dynamic process on the efficiency of the grinding is determined. Charpy hammers instrument were used to perform these modifications so that the momentary force of the resistance could be recorded with varying sample alignment, blade geometry changes and others. In addition, it was proposed to use a super fast camera (up to 1200 fps) to record the deformation of the sample and its destruction, in order to interpretation the burdens there. Under such idealized conditions, a range of variables has been identified that significantly affect the reduction of energy demand during grinding.

Image guidance protocol for synchrotron microbeam radiation therapy

The protocol for image-guided microbeam radiotherapy (MRT) developed for the Australian Synchrotron's Imaging and Medical Beamline (IMBL) is described. The protocol has been designed for the small-animal MRT station of IMBL to enable future preclinical trials on rodents. The image guidance procedure allows for low-dose monochromatic imaging at 50 keV and subsequent semi-automated sample alignment in 3D with sub-100 µm accuracy. Following the alignment, a beamline operation mode change is performed and the relevant beamline components are automatically aligned for the treatment (pink) beam to be delivered on the sample. Here, the small-animal MRT station, the parameters and procedures for the image guidance protocol, as well as the experimental imaging results using phantoms are described. Furthermore, the experimental validation of the protocol using 3D PRESAGE®dosimeters is reported. It is demonstrated that the sample alignment is maintained after the mode change and the treatment can be delivered within the same spatial accuracy of 100 µm. The results indicate that the proposed approach is viable for preclinical trials of small-animal MRT.

A modular and compact portable mini-endstation for high-precision, high-speed fixed target serial crystallography at FEL and synchrotron sources

The design and implementation of a compact and portable sample alignment system suitable for use at both synchrotron and free-electron laser (FEL) sources and its performance are described. The system provides the ability to quickly and reliably deliver large numbers of samples using the minimum amount of sample possible, through positioning of fixed target arrays into the X-ray beam. The combination of high-precision stages, high-quality sample viewing, a fast controller and a software layer overcome many of the challenges associated with sample alignment. A straightforward interface that minimizes setup and sample changeover time as well as simplifying communication with the stages during the experiment is also described, together with an intuitive naming convention for defining, tracking and locating sample positions. The setup allows the precise delivery of samples in predefined locations to a specific position in space and time, reliably and simply.