Deeply virtual Compton scattering off Helium nuclei with positron beams

Positron initiated deeply virtual Compton scattering (DVCS) off $$^4$$ 4 He and $$^3$$ 3 He nuclei is described. The way the so-called $$d-$$ d - term could be obtained from the real part of the relevant Compton form factor is summarized, and the importance and novelty of this measurement is discussed. The measurements addressed for $$^3$$ 3 He targets could be very useful even in a standard unpolarized target setup, measuring beam spin and beam charge asymmetries only. The unpolarized beam charge asymmetries for DVCS off $$^3$$ 3 He and $$^4$$ 4 He are also estimated, at JLab kinematics and, for $$^4$$ 4 He, also at a configuration typical at the future Electron–Ion Collider. Incoherent DVCS processes, in particular the ones with tagging the internal target by measuring slow recoiling nuclei, and the unique possibility offered by positron beams for the investigation of Compton form factors of higher twist, are also briefly addressed.

Improving interinstitutional and intertechnology consistency of pulmonary SBRT by dose prescription to the mean internal target volume dose

Purpose Dose, fractionation, normalization and the dose profile inside the target volume vary substantially in pulmonary stereotactic body radiotherapy (SBRT) between different institutions and SBRT technologies. Published planning studies have shown large variations of the mean dose in planning target volume (PTV) and gross tumor volume (GTV) or internal target volume (ITV) when dose prescription is performed to the PTV covering isodose. This planning study investigated whether dose prescription to the mean dose of the ITV improves consistency in pulmonary SBRT dose distributions. Materials and methods This was a multi-institutional planning study by the German Society of Radiation Oncology (DEGRO) working group Radiosurgery and Stereotactic Radiotherapy. CT images and structures of ITV, PTV and all relevant organs at risk (OAR) for two patients with early stage non-small cell lung cancer (NSCLC) were distributed to all participating institutions. Each institute created a treatment plan with the technique commonly used in the institute for lung SBRT. The specified dose fractionation was 3 × 21.5 Gy normalized to the mean ITV dose. Additional dose objectives for target volumes and OAR were provided. Results In all, 52 plans from 25 institutions were included in this analysis: 8 robotic radiosurgery (RRS), 34 intensity-modulated (MOD), and 10 3D-conformal (3D) radiation therapy plans. The distribution of the mean dose in the PTV did not differ significantly between the two patients (median 56.9 Gy vs 56.6 Gy). There was only a small difference between the techniques, with RRS having the lowest mean PTV dose with a median of 55.9 Gy followed by MOD plans with 56.7 Gy and 3D plans with 57.4 Gy having the highest. For the different organs at risk no significant difference between the techniques could be found. Conclusions This planning study pointed out that multiparameter dose prescription including normalization on the mean ITV dose in combination with detailed objectives for the PTV and ITV achieve consistent dose distributions for peripheral lung tumors in combination with an ITV concept between different delivery techniques and across institutions.