Homeopathic use of modern drugs: therapeutic application of the organism paradoxical reaction or rebound effect

When Samuel Hahnemann systematized homeopathy and the effects of drugs on the state of human health, he described the primary action of drugs and the following secondary and opposite reaction of the organism. Seeking to apply this secondary action or vital reaction of the organism as therapeutic method, he postulated the principle of similitude, i.e. the prescription to ill individuals of drugs that cause similar symptoms in the healthy (similia similibus curentur). In modern pharmacology, secondary action (vital reaction) of drugs is known as rebound effect or paradoxical reaction of the organism. It has been observed after discontinuation of several classes of palliative (enantiopathic) drugs, namely those that act according to the principle of contraries (contraria contrariis curentur). Although in this case it is associated with severe and fatal iatrogenic events, rebound effect might awaken a healing reaction when the very same drug is employed according to the principle of similitude. The validity of the principle of similitude is proved by scientific evidence on rebound effect, whereas conventional drugs primary (therapeutic, adverse and side) effects might be equated to pathogenetic manifestations and thus be homeopathically applied. For this purpose a homeopathic materia medica and repertory comprising 1,251 modern drugs was elaborated using the monographs described in The United States Pharmacopeia Dispensing Information as source (www.newhomeopathicmedicines.com). Thus, the therapeutic range of homeopathy is broadened through the addition of hundreds of new medicines that might be employed in every kind of disease including countless modern clinical syndromes.

Injuries and vital reactions patterns in hanging

Hanging is a form of ligature strangulation in which the force applied to the neck is derived from the gravitational drag of one?s own body weight. A furrow - dessication is the most common form of ligature mark on the skin. The furrow is a postmortem phenomenon due to ligature pressure and it is more detectable as the suspension time becomes longer. Vital reaction is a phenomenon that shows if the injury was premortal. Vital signs could be present at the injury site, thus it is termed as local, but they could also be remote from the injury site, and then they are termed general vital signs. The presence and recognition of any vital reaction in each pathoforensic case indicate vitality of certain injury, which is sometimes exceptionally useful in solving the case under investigation. Although in cases of hanging there is usually no question about the vitality of injury, this does not mean that one should not recognize the type of vital reactions and location of occurrence of these phenomena in such cases. Most often they can be also useful in the reconstruction of the mechanism. This paper presents most common vital reactions in hanging, with explanation of their underlying mechanisms, and their significance in forensic pathology is pointed out.