Alternative treatment horizon for polycystic ovarian syndrome through Homoeopathy

Background: Polycystic ovarian syndrome (PCOS) is a complex hormonal and metabolic disorder characterized by oligomenorrhea or amenorrhea, hyperandrogenism and infertility. Global prevalence of PCOS is estimated to be between 06% and 26%. Homoeopathy, being a system of holistic healing can be accepted as one of the alternative treatments for PCOS. Aim & Objective: The aim of the study is to review clinical data, where the intervention was aimed to treat PCOS through Homoeopathy. The objective of the study is to identify the therapeutic approach, assessment criteria, treatment outcomes through an alternative therapy i.e., Homoeopathy in cases of PCOS. Methods: A systematic literature search was conducted in the month of June2021 following International/National search databases for all clinical studies published in the period from 2000 to 2021. This search was aimed to target the entire literature of randomized trials or controlled trials, observational studies case studies/reports on PCOS in homoeopathy. Result:28 articles related to Homoeopathy on PCOS were identified. Out of these 28studies, 22 studies (01 RCT, 02 NRCT,06 observational studies,04 case series and 09 case reports) were included in this review. All studies were published in peer reviewed journals. Conclusions: To establish the evidence based efficacy of the homoeopathic treatment in cases of RCT more pragmatic studies need to be planned in the future based on proper diagnostic criteria.

High Dilutions of a Drug of Covid-19 Origin Show Difference in Ranks

High dilutions (HDs) of drugs, used in Homeopathy, are prepared in aqueous EtOH (ethanol) through serial dilution accompanying mechanical agitation or succussion, and are called potencies. The potencies from the rank 12 onwards are too dilute to contain any original drug molecules. Do the potency ranks show any difference from each other? Do serial dilution and succussion contribute to the difference in potency ranks? This study aims to address these two questions. The throat swab of a Covid-19 patient was preserved and diluted with aqueous EtOH 90% to prepare the mother tincture (MT) and five different potencies of Covid named Covidinum. These potencies and their solvent media were analysed by electronic and vibrational spectroscopy. Charge transfer (CT) and proton transfer interactions occur during preparation of the potencies. The FT-IR spectra of all the test samples after normalization show difference from each other with respect to O-H stretching and bending (v2) bands. Serial dilution and succussion contribute to the observed difference in ranks and CT interactions.

Revisiting prophylaxis of homeopathic interventions in COVID 19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by novel beta-coronavirus has emerged as a cause of coronavirus pandemic (COVID-19) declared by Public Health Emergency of International Concern (PHEIC). Korean oriental medicine, Traditional Chinese Medicine (TCM), and Indian systems of medicine known as AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha and Sowa-Rigpa and Homeopathy) had implemented various prophylactic measures and interim treatment guidelines in prevention and treatment for COVID -19 cases. However, even though different approaches were implemented to break the epidemic chain, we have not reached herd effect or herd immunity in the Indian population. Therefore, in this ongoing COVID-19 pandemic, a specific study on immune markers of IL-6 (Interleukin-6), D-Dimer, Ferritine, CRP (C-reactive protein) with SARS CoV-2 specific IgG & IgM antibodies need to be investigated for generating hard-core evidence for homeoprophylaxis in terms of immunity response. Therefore, there seems to be a need to revisit the program of homeoprophylaxis in the COVID -19 pandemic.

Homeopathic Treatment of Rectal Prolapse in a Kitten

Rectal prolapse be either partial or incomplete in nature and is defined as double layer evagination of the rectum through the anal canal. The common associated causations which can be seen in kittens are severe endoparasitism, enteritis, and associated tenesmus (Fossum, 2002). Rectal prolapse is the one of the most encountered surgical conditions involving the rectum in all domestic animal species (Tyagi and Singh, 1993). Surgical intervention is the most common treatment methodology adopted but however, in cases where surgery is not indicated, required, not opted by the owner, becomes a challenge to treat. Therefore, finding alternative therapies for clinical management is the need of hour. The objective of this study is to report successful management of rectal prolapse in a 5-month-old kitten having 4 episodes of prolapse in five days. The homeopathic medicines used in this case were Sepia 200C and Ruta g. 200C. The patient revealed a favourable response by 2nd day of the treatment and complete healing was observed on 7th day. This therapeutic protocol used was conclusive and it re-established the normal intake of food and energy level. Hence, homeopathic treatment can be considered as an alternative therapy for clinical management of rectal prolapse in a Felines and Canines.

Particle Characterisation of Traditional Homeopathically Manufactured Medicine Cuprum metallicum and Controls

Background: Homeopathy is highly controversial. The main reason for this is its use of very highly dilute medicines (high homeopathic potencies, HHP), diluted beyond the Avogadro/Loschmidt limit. Research using several different methods has demonstrated the presence of particles, including nanoparticles of source material, in HHPs. This study aims to verify the results of a previous publication that detected the presence of particles in all dilutions. Methods: We used the Nano Tracking Analyzer (NTA) to examine dilutions of a commonly used homeopathic medicine, an insoluble metal, Cuprum metallicum, for the presence of particles. The homeopathic medicines tested were specially prepared according to the European pharmacopoeia standards. We compared the homeopathic dilutions/dynamizations with simple dilutions and controls including a soluble medicine. Results: We observed the presence of solid material in all preparations including HHPs (except for pure water). The measurements showed significant differences in particle sizes distribution between homeopathic manufacturing lines and controls. Conclusion: Homeopathic medicines do contain material with a specific size distribution even in HHPs diluted beyond the Avogadro/Loschmidt limit. This specificity can be attributed to the manufacturing and potentization process. This material demonstrates that the step-by-step process (dynamized or not) does not match the theoretical expectations in a dilution process. The starting material and dilution/dynamization method influences the nature and concentration of these NPs.

Different Perspectives of Homeopathic Research Seal the Year 2021

In this last 2021 issue, five articles are published concerning different aspects of homeopathic research, from a review of clinical studies on Polycystic Ovarian Syndrome and the therapeutic potential of homeopathy to treat these cases (Dewan et al., 2021) to a detailed systematic analysis of nanoparticles suspended in homeopathic preparations (Van Wassenhoven et al., 2021). In between, some interesting reports can also be found, as a case report about the successful treatment of a rectum prolapse in a kitten in a period of a few days with no need of surgery (Makker and Arora, 2021); an opinion article (update article) reported the necessity to develop clinical studies on homeoprofilaxy of Covid-19 in which the key aspects of immunocompetence could be evaluated, such as the serum levels of cytokines, mainly those related to the systemic inflammatory syndrome such as IL-6, and of neutralizing IgG and IgM (Patil, 2021); and an original article about the physicochemical properties of a Covid-19 nosode, in which different patterns were described using spectrophotometric methods, resulting in an electronic signature of each potency (Kumar Singh et al., 2021). Enjoy the reading and happy 2022 for us all! IJHDR Editorial Team

REDIMEH Project:Ibero-American Integrative Network for Clinical Research in Homeopathy

If there were one lacking or insufficient issue which conscious medical orientated homeopaths could regret, it would be probably high quality clinical research. A big part of the homeopathic community still insists in the traditional ways of building knowledge, leading us nowhere. There is now an agreement between clinical researchers that there have been done enough efforts with Randomized Control Trials (RCT). But what we need today is good quality scientific research that could improve our daily practice. This article introduce the REDIMEH, an Ibero-American Integrative Network for Clinical Research in Homeopathy, horizontal in structure, with no political objectives, with the only intention of joining efforts in order to obtain enough clinical data to draw out valid conclusions. Keywords: REDIMED, atopic dermatitis, clinical research.  Projeto REDIMED: Red Integrada Ibero-Americana para Pesquisa Clínica em Homeopatia ResumoSe pudermos apontar uma questão, a qual os verdadeiros médicos homeopatas podem se lamentar, esta deveria ser a falta ou insuficiéncia de pesquisas clínicas de alta qualidade. Uma grande parte da comunidade homeopática ainda insiste nas formas tradicionais de construção de conhecimento, levando-nos a lugar algum. Existem pontos bem estabelecidos pelos pesquisadores clínicos que tem se esforçado muito com a realização de Ensaios Controlados Randomizados (RCT). O que mais precisamos hoje é de investigação científica de boa qualidade, que possa melhorar a nossa prática diária. Este artigo apresenta o projeto REDIMEH, uma Rede Integrada Ibero-Americana para Pesquisa Clínica em Homeopatia, de estrutura horizontal, sem objetivos políticos, com a intenção de unir esforços no sentido de obter dados clínicos suficientes para chegarmos a conclusões válidas para a prática clínica diária. Palavras-chave: REDIMED, dermatite atópica, investigação clínica.  Proyecto REDIMEH: Red Iberoamericana Integrativa de Investigación Clínica en Homeopatía ResumenSi hubiera uma cuestión de la cual los médicos homeopatas podrían pesar, sería probablemente la investigación clínica de alta calidad. Una gran parte de la comunidad homeopática sigue insistiendo en las formas tradicionales de construcción del conocimiento, que nos conduce a ninguna parte. En la actualidad, existe un acuerdo entre los investigadores clínicos, que ya se han hecho lo suficiente con los esfuerzos de control de ensayos aleatorios (RCT). Pero lo que necesitamos hoy es la investigación científica de buena calidad que pueda mejorar nuestra práctica diaria. Este artículo presentará el REDIMEH, uma Red Iberoamericana Integrativa de Investigación Clínica en Homeopatía, con una estructura horizontal, sin objetivos políticos, con la única intención de unir esfuerzos con el propósito de obtener datos clínicos suficientes para sacar conclusiones válidas. Palabras-clave: REDIMED, dermatitis atópica, investigación clínica  Correspondence author: Jose Eizayaga, [email protected], www.maimonides.edu How to cite this article: Eizayaga J. REDIMEH Project: Ibero-American Integrative Network for Clinical Research in Homeopathy. Int J High Dilution Res [online]. 2009 [cited YYYY Month dd]; 8(27): 50-52. Available from: http://journal.giri-society.org/index.php/ijhdr/article/view/340/392. ÂÂÂ

The emergence of modern therapeutic similarity

One of the roots of modern therapeutic similarity might be retraced to the work of Samuel Hahnemann at the end of the 18th century. His particular formulation arose from an original synthesis of traditional therapeutic similarity, dating from classic Antiquity and mantained as an undercurrent in medical thinking, and contemporary theories, particularly counter-irritation (antagonistic fever) theory. Against historical readings asserting that modern therapeutic similarity is either a mere a continuation of the ancient, or a historical orphan, it is possible to verify that Hahnemann’s work belonged within the specific framework of 18th medical science. The formulation of modern therapeutic similarity is best described as a process combining both continuity and epistemological break. Keywords: History of Medicine; 18th century; Pharmacology; Peruvian bark; Modern therapeutic similarity.  O surgimento da semelhança terapéutica moderna Resumo Uma das raízes da semelhança terapéutica moderna pode ser localizada na obra de Samuel Hahnemann, no final do século XVIII. Sua formulação particular surgiu da síntese original da semelhança terapéutica tradicional, procedente da Antigüidade clássica e conservada subterraneamente no pensamento médico, com teorias contemporâneas, especialmente a teoria da contra-irritação (febre antagonista). Por oposição a leituras históricas que afirmam que semelhança terapéutica moderna é uma mera continuação da antiga ou, alternativamente, um ófão histórico, pode-se constatar que a obra de Hahnemann corresponde ao marco específico da ciéncia médico do século XVIII. A formulação da semelhança terapéutica parece ser melhor compreendida como um processo que combina continuidade e ruptura epistemológicas. Palavras-chave: História da Medicina; século 18; Farmacologia; semelhança terapéutica moderna.  El surgimiento de la similaridad terapéutica moderna Resumen Una de las raíces de la similaridad terapéutica moderna puede ser localizada en la obra de Samuel Hahnemann al final del siglo XVIII. Su formulación particular surgió de la síntesis original de la similaridad terapéutica tradicional, procedente de la Antigüedad clásica y conservada subterráneamente en el pensamiento médico, con teorías contemporáceas, especialmente la de la contrairritación (fiebre antagonista). En oposición a lecturas históricas que afirman que la similaridad terapéutica moderna es una mera continuación de la antigua o un huérfano histórico, se puede constatar que la obra de Hahnemann corresponde al marco específico de la ciencia médica del siglo XVIII. La formulación de la similaridad terapéutica moderna parece ser mejor comprendida como um processo que combina continuidad y ruptura epistemológicas. Palabras-clave: Historia de la Medicina; siglo 18; Farmacología; similitud terapéutica moderna.  Correspondence author: Silvia Waisse Priven, [email protected] ; http://www.pucsp.br/pos/cesima How to cite this article: Waisse Priven S. The emergence of modern therapeutic similarity. Int J High Dilution Res [online]. 2008 [cited DD Mmm YYYY]; 7(22): 22-30. Available from: http://journal.giri-society.org/index.php/ijhdr/article/view/252/335. ÂÂÂ