TREND OF TEMPERATURE AND RELATIVE HUMIDITY IN EAST SIANG DISTRICT OF ARUNACHAL PRADESH, INDIA

A study was conducted in the East Siang District of Arunachal Pradesh for the time period from 2000 to 2018 in order to study the temperature and relative humidity parameters of climate change in the study area. The study was based on secondary data collected from the regional meteorological centre wherein official data was collected for the years 2000 to 2018 for temperature and 2006 to 2018 for relative humidity. It was observed that maximum temperature in the study area exhibited an increasing trend during the study period. A monthly temperature study also showed that maximum temperature for the study area exhibited a significant increase during the months of February, July and August. The average annual Relative Humidity for East Siang during 2006-2018 was found to be 76.72 and 77.04 at 0830 hrs and 1730 hrs IST respectively. The monthly study of the Relative Humidity showed significant increase for the evening hours of 1730 hours IST during the months of April, and a significant decreasing trend for the months of September and October

Abstract P324: Your Brain May Be "HOTTER" Than You Think, Results From Phase I Check Brain Temperature Study

Background: Hypothermia is a known neuronal protecting agent and used in post cardiac arrest. However, its use for stroke and brain trauma has not made any progress due to the lack of accurate way of measuring brain temperature. Hence, hypothermic degree and duration for it to be therapeutic is unknown. The phase I Check Brain Temperature Study was to define regional brain temperatures in normal individuals via MRI thermometry. The established brain temperature map can be used as the baseline to provide therapeutic hypothermia. Method: Temperatures of 5 regions of interest (ROI) of brain (frontal lobe, thalamus, hypothalamus, occipital lobe and cerebellum) were measured in 10 healthy individuals by using proton resonance frequency MRI spectroscopy single voxel method. The scanning protocol include a whole brain anatomical images, (3DFSPGR : TR/TE=150/3.9ms, FOV=24cm,matrix=256x256, slice thickness =1 mm.) and spectroscopy PRESS (TR/TE=1500/144 ms, 8 nex, 2 x 2 x 2 cm^3) on a GE 3T scanner. Ten right handed men (18<age<80) were recruited and their oral and tympanic temperatures were monitored. Average whole head temperature=average of oral temp+tympanic temp and average brain temp=average of temp of 5 regions of interest. Two tails, paired t-test used to compare temps between subjects and ROIs. Results: Average temperature differences between brain (38.2 °C) and head (36.5 °C) is 1.8 °C (p< 0.0000002). Thalamus has the highest temperature among all ROIs in brain. Brain temperature > oral temperature > tympanic temperature. Conclusion: Brain temperatures may not correlate to body temperatures and there is a regional difference. Our finding will be used as the baseline brain temperature map when hypothermia is applied in patients with hemisphere stroke in the phase II study.