Neurological Complications of Biological Treatment of Psoriasis

In the available literature, little attention has been paid to the assessment of psoriasis and the biological therapy used for it and the nervous system. The purpose of this article is to discuss the relationship between psoriasis and the nervous system as well as to analyze the mechanisms that lead to neurological complications during anticytokine therapies in psoriasis. However, this connection requires further analysis. The use of biological drugs in psoriasis, although it yields positive therapeutic results, is not without numerous side effects. Serious neurological side effects of the therapy are most often visible with the use of anti-TNF-alpha, which is why patients should be monitored for their potential occurrence. Early detection of complications and rapid discontinuation of treatment with the drug may potentially increase the patient’s chances of a full recovery or improvement of his/her neurological condition. It also seems reasonable that, in the case of complications occurring during anti-TNF-alpha therapy, some of the drugs from other groups should be included in the therapy.

Physico-chemical monitoring of biodegradation of furfural from oil industry effluents from the Arzew refinery (Oran) Algeria

Furfural is one of the petroleum products posing a potential danger to the environment and human health. However, the decontamination of these pollutants released into the environment is primarily governed by biodegra-dation processes. This study is based on biodegradation kinetics at increasing concentrations of furfural by natural mixed culture in order to assess the potential of this process in the elimination of furfural from petrochemical effluents from the ARZEW refinery. This biodegradation was measured through physicochemical parameters such as pH, electrical conductivity, con-centration of hydrocarbons, the chemical oxygen demand (COD), biochemi-cal oxygen demand (BOD5) and the concentration of furfural. The results obtained show at a concentration of 250ppm of injected furfural: a decrease in pH 4.9 and an increase in other parameters (conductivity 3450 μS.cm-1, HC 102 mg / l; furfural 210 ppm, COD 327mg / l, BOD5 98mgO2 / l. The study findings indicated that the injection of these effluents with concentrations greater than 180 ppm leads to values of pH, EC, HC, Furfural, COD, BOD5 which do not comply with direct discharge standards and disrupt biological treatment. The high levels of furfural not only cause a pollution problem but can also disrupt the functioning of bacteria at the biological treatment level. Therefore, dilution with the filtration wash water before switching to biologi-cal treatment is recommended in order to reduce the concentrations below 180 ppm.

Decolorization of the benzidine-based azo dye Congo red by the new strain Shewanella xiamenensis G5-03

Shewanella xiamenensis G5-03 was observed to decolorize the azo dye Congo red in synthetic wastewater. The influence of some factors on the dye decolorization efficiency was evaluated. The optimal decolorization conditions were temperature 30-35 °C, pH 10.0, incubation time 10 h, and static condition. The kinetic of Congo red decolorization fitted to the Michaelis–Menten model (Vmax = 111.11 mg L-1 h-1 and Km = 448.3 mg L-1). The bacterium was also able to degrade benzidine, a product of azo bond breakage of the Congo red, which contributed to reduce the phytotoxicity. The ability of S. xiamenensis G5-03 for simultaneous decolorization and degradation of Congo red shows its potential application for the biological treatment of wastewaters containing azo dyes.