Zinc oxide is technologically important and ZnO thin layers are widely used in sensors, transducers and catalysts designing. However, after the introduction of nanoscience and nanotechnology the gear has been shifted to its smaller counterpart in contrast to its bulk one. In this review typical synthesis procedure, growth process, classical property, and a few biological perspectives of zinc oxide nanostructures have been highlighted. In coming years new synthetic strategy, benign fabrication will be introduced with plethora of versatile and beneficial applications based on zinc oxide nanostructures.