Mobilizing COVID-19 Testing: Impact and Challenges

Introduction/Objective In response to the rapidly evolving COVID-19 pandemic, Sanford Health developed a mobile diagnostic testing program capable of reaching geographically dispersed sites and communities. These mobile laboratories provided on-site testing and sensitive detection of SARS-CoV-2 by leveraging Cepheid’s GeneXpert platform, enabling rapid reporting of results directly to the patient and physician. Aggregation of these results allowed monitoring population infection rates and public health reporting. Methods/Case Report Within 3 weeks of conception, the first mobile unit was designed, engineered and deployed. Key requirements for successful implementation included mobile lab licensure, CLIA certification, COLA enrollment, Quality and Risk assessments, inventory management, lab maintenance and ongoing monitoring. Testing was performed using the Xpert Xpress SARS-CoV-2 test and the population tested were primarily asymptomatic individuals. Results (if a Case Study enter NA) Between May 3rd, 2020 and June 23rd, 2021, a total of 31,148 Xpert Xpress SARS-CoV-2 tests were run across 3 mobile laboratories, with an average of 600 tests performed per week. The percent positivity ranged from 0% to 5.8%, reaching highest positivity in week beginning May 10th, 2020. The average turnaround time from sample collection to result verification was 2.0 hours, and the average time from sample receipt to result verification was under 1 hour. Conclusion Sanford Health’s mobile testing program brings SARS-CoV-2 PCR testing to the community and dramatically reduces the time from sample collection to result reporting compared with traditional testing labs, enabling rapid intervention following a positive result. The flexibility of the GeneXpert platform, including the instrument’s robustness, the independently functioning analyzers, and the wide range of tests available, makes it particularly well suited to mobile laboratories. This program demonstrates the impact of on-site testing and highlights the challenges that were overcome for successful implementation, providing a blueprint to support the development of other mobile laboratories in the US.

Aerodynamics Analysis on Wings with Winglets and Vortex Generators

This project was based on the principle of designing, simulating and developing an inexpensive, aerodynamically efficient and regular class electric powered RC aircraft. This prototype was designed to have the maximum strength to weight ratio with minimum drag coefficient (and highest lift coefficient). Moreover, all constraints provided by SAE International competition were followed. The investigation was conducted for the complete airplane and for wing optimization. The model was numerically investigated with ANSYS Fluent 16.1 through the SST K-Omega turbulence model at Reynolds number of 360,000. Once the results were obtained, model and result verification were done by wind tunnel test to validate the data. It was concluded that the airplane with 45° winglet has the highest lift force with minimal drag and 45° winglet was further modified with rectangular and triangular vortex generators in order to further enhance its aerodynamic efficiency for a range of Angle of Attacks (AOA).

Verified Numerical Computations and Related Applications

The author has been engaged in the study of numerical computations with result verification starting from 1990.

Achieving Universal Assured Fine-Grained Query Result Verification for Secure Search Scheme over Encrypted Cloud Data

Secure pursuit strategies over encoded cloud information enable an approved client to inquiry information documents of enthusiasm by submitting scrambled question catchphrases to the cloud server in a protection safeguarding way. In any case, practically speaking, the returned question might be mistaken or deficient in the exploitative cloud condition. For instance, the cloud server may deliberately preclude some qualified outcomes to spare computational assets and correspondence overhead. In this manner, a well-working secure inquiry framework need to provide a question comes about check system that permits the knowledge client to verify comes about. In this paper we outline a protected, efficiently included, and fine-grained question comes about corroboration instrument, by which, given an prearranged inquiry comes about set, the query client not wholly can check the rightness of every in order record in the set yet in addition can as well check what number of or which qualified information documents are not returned if the set is inadequate before unscrambling. The check plot is free coupling to concrete secure inquiry procedures and may be effectively coordinated into any safe question conspire. We accomplish the target by building secure check question for scrambled cloud information. Moreover, a short mark strategy with greatly little stockpiling cost is proposed to ensure the credibility of confirmation protest and a check question ask for method is introduced to enable the inquiry client to safely get the coveted check protest. Execution assessment demonstrates that the proposed plans are down to earth and proficient.

Seismic Sifting and Design of a Multi Storeyed Building by Various Materials

The principle objective of this project is to analyse and design a multi-storied building [g + 10 (3 dimensional frame)] using staad-pro for different cases like normal building seismic resist building and steel frame building. The design involves load calculations and analysing the whole structure by staad.pro. Staad.pro features a state-of-the-art user interface, analysis and design to visualization and result verification, staad.pro is the professional’s choice. Initially we started with the analysis of simple 2 dimensional frames and manually checked the accuracy of the software with our results. The results proved to be very accurate.