Different radiographic imaging modalities with a proton computed tomography demonstrator

Proton computed tomography aims at improving proton-beam therapy, which is an established method to treat deep-seated tumours in cancer therapy. In treatment planning, the stopping power (SP) within a patient, describing the energy loss of a proton in a tissue, has to be known with high accuracy. However, conventional computed tomography (CT) returns Hounsfield units (HU), which have to be converted to SP values to perform the required treatment planning, thus introducing range uncertainties in the calculated dose distribution. Using protons not only for therapy but also for the preceding planning CT enables the direct measurement of the SP. Hence, this imaging modality eliminates the need for further conversion and therefore offers the possibility to improve treatment planning in proton therapy. In order to examine the principles of such a proton CT (pCT) setup, a demonstrator system, consisting of four double-sided silicon strip detectors and a range telescope, was built. The performance of the pCT demonstrator was tested with measurements at the MedAustron facility in Wiener Neustadt, Austria. In this paper, 2D imaging modalities going beyond the idea of a standard proton radiography, will be discussed. Namely, fluence loss imaging and scattering radiography results obtained with the demonstrator will be shown. The advantage of these modalities is that they do not rely on an additional energy measurement and can therefore be conducted only with the tracker of the demonstrator.

Three-dimensional synchronous proton radiography for dynamic magnetic fields in laser-produced high-energy-density plasmas

Understanding the generation and evolution of magnetic fields in high-energy-density plasmas is a major scientific challenge in broad research areas including astrophysics, cosmology, and laser fusion energy. However, the fully three-dimensional (3D) topologies of such dynamic magnetic fields are still unknown yet. Here we report experiments of the first 3D synchronous proton radiography for self-generated magnetic fields in respectively laser-produced low-Z CH and high-Z Cu plasmas. The radiography images show that abundant 3D filamentary structures of magnetic fields grow up in coronal region of CH plasmas, while for Cu, the fields are majorly compressed along the dense surface region whose internal structures are pretty vague. These results are reproduced and explained by a combination of radiation-magnetohydrodynamic, particle-in-cell and Vlasov-Fokker-Planck simulations, where the cross-scale effects of Biermann battery, Nernst advection, resistive diffusion, Righi-Leduc and particularly kinetic Weibel instability are all taken into account. Our findings provide much enlightenment to the role of magnetic field generation in implosion and hohlraum dynamics of laser fusion.

Demonstration of TNSA proton radiography on the National Ignition Facility Advanced Radiographic Capability (NIF-ARC) laser

Proton radiography using short-pulse laser drivers is an important tool in high-energy density (HED) science for dynamically diagnosing key characteristics in plasma interactions. Here we detail the first demonstration of target-normal sheath acceleration (TNSA)-based proton radiography the NIF-ARC laser system aided by the use of compound parabolic concentrators (CPCs). The multi-kJ energies available at the NIF-ARC laser allows for a high-brightness proton source for radiography and thus enabling a wide range of applications in HED science. In this demonstration, proton radiography of a physics package was performed and this work details the spectral properties of the TNSA proton probe as well as description of the resulting radiography quality.

Full treatment of the proton radiography technique for laser-driven capacitor-coil targets

Ultrafast proton radiography has been frequently used for direct measurement of the electromagnetic fields around laser-driven capacitor-coil targets. The goal is to accurately infer the coil currents and their magnetic field generation for a robust magnetic field source that can lead to many applications. The technique often involves numerical calculations for synthetic proton images to reproduce experimental measurements. While electromagnetic fields are the primary source for proton deflections around the capacitor coils, stopping power and small angle deflection can also contribute to the observed experimental features. Here we present a comprehensive study of the proton radiography technique including all sources of proton deflections as a function of coil shapes, current magnitudes, and proton energies. Good agreements were achieved between experimental data and numerical calculations that include both the stopping power and small angle deflections, particularly when the induced coil currents were small.

Low Intensity Beam Extraction Mode on the Protom Synchrotron for Proton Radiography Implementation

Proton radiography is one of the most important and actual areas of research that can significantly improve the quality and accuracy of proton therapy. Currently, the calculation of the proton range in patients receiving proton therapy is based on the conversion of Hounsfield CT units of the patient's tissues into the relative stopping power of protons. Proton radiography is able to reduce these uncertainties by directly measuring proton stopping power. The study demonstrates the possibility of Protom synchrotron-based proton therapy facilities to operate in a special mode which makes it possible to implement proton radiography. This work presents the status of the new low beam intensity extraction mode. The paper describes algorithms of low flux beam control, calibration procedures and experimental measurements. Measurements and calibration procedures were performed with certified Protom Faraday Cup, PTW Bragg Peak Chamber and specially designed experimental external.