The processes of forming working relationships with children and adolescents are often different than those with adults because of their physical, psychological, cognitive, emotional, and social stages of development. Additionally, they are at risk for many unique problems due to their dependency on and vulnerability to harm by adults. Their problems may be related to an absence of adequate family support and appropriate adult models, exposure to unhealthy social systems and traumatic situations, attachment issues, and difficulties with emotional regulation. Peer conflicts can also create distress for youth. Further, while children and adolescents are dependent on adults to get most of their needs met, they are often distrusting of adults, including social workers. The purpose of this chapter is to consider how social workers can engage with members of this population and develop relationships with them based on trust.