catecholamine response
Recently Published Documents


TOTAL DOCUMENTS

203
(FIVE YEARS 4)

H-INDEX

29
(FIVE YEARS 1)

2021 ◽  
pp. 000313482110516
Author(s):  
Navpreet K. Dhillon ◽  
Yassar M. Hashim ◽  
Geena Conde ◽  
George Phillips ◽  
Nicole M Fierro ◽  
...  

Background Traumatic brain injury (TBI) results in an elaborate systemic cascade of secondary injury elicited in part by an intrinsic catecholamine response, which ultimately leads to changes in inflammation and coagulopathy. Attenuation of this catecholamine response with agents such as propranolol confers a survival advantage. The related impact of propranolol on venous thromboembolism (VTE) after TBI is largely unknown. Study Design A single institution retrospective review was conducted of all TBI patients requiring intensive care unit (ICU) admission with an injury severity scale (ISS) ≥ 25 from January 2013 to May 2015. Patients who received at least one dose of propranolol within 24 hours of admission (PROP) were compared to patients who did not receive any doses of propranolol (NPROP) during their hospitalization. Results Of the 131 patients analyzed, 31 (23.7%) patients received propranolol. The PROP cohort was more severely injured overall (ISS 29 vs 26.5, P = .02). While unadjusted VTE rates were similar (16.1% vs 19.0%, P = .72), the adjusted VTE rate was lower in the PROP cohort (AOR 0.20 (95% CI 0.04-0.97), adjusted P-value < .05). Conclusion Propranolol use in TBI patients who have sustained critical injuries may mitigate the risk of VTE. The mechanism by which this outcome is achieved requires further investigation.


2020 ◽  
Vol 11 ◽  
Author(s):  
Fiona Limanaqi ◽  
Carla Letizia Busceti ◽  
Francesca Biagioni ◽  
Francesco Fornai ◽  
Stefano Puglisi-Allegra

HORMONES ◽  
2020 ◽  
Vol 19 (3) ◽  
pp. 395-402
Author(s):  
Csaba Sumanszki ◽  
Krisztian Kovacs ◽  
Gellert Balazs Karvaly ◽  
Erika Kiss ◽  
Erika Simon ◽  
...  

2019 ◽  
Vol 597 (5) ◽  
pp. 1337-1346 ◽  
Author(s):  
Ankit B. Shah ◽  
Mary Z. Bechis ◽  
Marcel Brown ◽  
Jennifer Michaud Finch ◽  
Garrett Loomer ◽  
...  

Synapse ◽  
2015 ◽  
Vol 69 (8) ◽  
pp. 385-395 ◽  
Author(s):  
Anushree N. Karkhanis ◽  
Nancy J. Alexander ◽  
Brian A. McCool ◽  
Jeffrey L. Weiner ◽  
Sara R. Jones

2015 ◽  
Vol 47 ◽  
pp. 410
Author(s):  
Brandi Price ◽  
Daniel Blessing ◽  
John Quindry ◽  
Gretchen Oliver ◽  
Michael Esco ◽  
...  

2014 ◽  
Vol 26 (8) ◽  
pp. 628-633 ◽  
Author(s):  
Rahman Abbasivash ◽  
Mir Moosa Aghdashi ◽  
Behzad Sinaei ◽  
Fatemeh Kheradmand

HORMONES ◽  
2013 ◽  
Vol 12 (2) ◽  
pp. 283-291 ◽  
Author(s):  
Angeliki Krikri ◽  
Vasileios Alexopoulos ◽  
Emmanouil Zoumakis ◽  
Paraskevas Katsaronis ◽  
Evangelos Balafas ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document