Effect of Prosopis Farcta, Urtica Dioica and Disper root on Vegetative Growth, Nutrients Contents of cv. Shahreban Pomegranate Transplant

This research was conducted on pomegranate transplants in a lath house during the growth season of 2020 of college of Agricultural engineering science, university of Duhok, to investigate the impact of spraying of Prosopis Farcta, Urtica Dioica and Disper root with 0,100, and 200 mg.L-1 concentration, with 0,100, and 200 mg.L-1 concentration and with (0, 75, and 150 mg.L-1) concentration respectively, on vegetative growth, nutrients contents of pomegranate transplants. The collected data indicate that the spraying of Prosopis Farcta extract, Urtica Dioica and Disper root especially at 200, 200, and 150 mg.L-1 respectively resulting in a considerable increase in the majority of the examined parameters. At high concentrations, the interaction of three examined components resulted in the maximum values of branches number 14.57, transplant height 143.67 cm, leaves number 157.33, Chlorophyll 48.97, Roots number 10, Root length 42.67 cm, leaf nitrogen content 2.507 %, phosphorus 0.267 % and potassium 1.433 %.

Natural Product Chemistry Research in Iraq

Today's west an east scientists developed synthetic drugs but because of problems of the side effects and high cost in addition to resistant developed which not happened in using natural drugs this push the scientist in all over the world to look for new drugs from natural compounds. In Iraq. Since 1980 up today we started a plan led by scientist in Chemistry ,Pharmacology, Physician ,Biology in all universities & medical research centers and we started to develop anew methods for extraction ,isolation,identication of active constituent and trying the active constituent biologicaly and Pharmacologicaly in invitro and invivo on experimental animals . We started screening of more than thousand plants which indigenous in Iraq and take the knowledge from folkloric physician and old information about these from ancient books and references we found around two hundred promising plants we developed methods of extraction , isolation using chromatography and trying to evaluate their efficacy .We managed to prepare drugs to treat warts from ficus caria vitexin from cratagus azorolus, prosoptatin anew antihyperlipidemic drug from prosopis farcta etc. A new method of isolation and identification by new phytochemical methods and new experimental tool for each active constituent are as example how to separate alkaloids, cardiac glycosides inotropic agents , polyphenoles etc. In addition to bacteriological ,toxi-pathological methods then pass to prepare anew natural drugs prepared with highly sophisticated methods and with highly efficiency which may be better than synthetic drugs and more safe .

Curative Effects of Ethanol Extract of Prosopis Farcta (Syrian Mesquite) Against Ethylene Glycol Induced Urolithiasis in Male Albino Rats

The present study was designed to evaluate the antiurolithiatic activity of Prosopis farcta (P. farcta) ethanol fruit extract in ethylene glycol (EG) induced urolithiasis in male albino rats. Lithiasis was induced by oral administration of EG 1% in male albino rats for 28 days. Seventy eight male albino rats weighing 250-300g were used and divided into six experimental groups. Group A is a control group received standard rat chow and tap water ad libitum, while, rest of groups namely group B, C, D, E, F animals received 1% EG in water for 28 days, then from day 15 to day 28 in addition to EG administration, group C received cystone, group D, E and F received 100, 200 and 300 mg/kg body weight (B.W.) of ethanol fruit extract of P. farcta respectively. On day 28, blood was collected for serum biochemical (serum uric acid, creatinine, urea, electrolytes measurements, malondialdehyde (MDA) and superoxide dismutase (SOD)) determinations. While urine was collected to microscopic analysis of formed crystals besides the kidney weight/ B.W. ratio and B.W. gain/ loss values were determined. Intermediate dose (200mg/kg B.W.) of P. farcta extract significantly decreased serum creatinine, urea, MDA and non-significantly recovered SOD toward control value in group E as compared to group B, also significant elevation in kidney weight/ B.W. ratio and reduction in B.W. gains in group B occurred as compared with group A. In conclusion: P. farcta fruit extract has potentially therapeutic effects on EG induced kidney stone which can be used as effective antiurolithiatic agent rather than cystone.

Vitexin Anew Antihypertensive Drug (Isolated from prosopis farcta [Iraq endogenus] plants)

Vitexin was isolated and identified from pods of prosopis farcta (Iraqi endogenous). In vitro and in vivo cardiovascular actions of vitexin were studied. Vitexin produced positive inotropic effect which was not related to B1 adrenergic receptor activation. Vitexin has a vasodilator activities and it could reverse thevasoconstrictor response of isolated pulmonary artery to potassium chloride and phenylphrine. Vitexin has produced a significant increase in ejection fraction in volunteers with mild heart failure. Also vitexin has produced a significant increase in urinary flow and urinary sodium and potassium excretions in healthy and mild hypertensive volunteers, it’s significantly reduced mean arterial blood pressure of the mild hypertensive volunteers. The positive inotropic effect of vitexin is most properly related to the inhibition of phosphodiesterase enzyme by vitexin. The vasodilator activities of vitexin could be mostly associated to the increase in cGMP (attributed to phosphodiesterase inhibitory effect of vitexin) and the activation of K+-channels. The diuretic effects of vitexin could be attributed to the inhibition of Na-Cl symporter system in the renal distal tubule. The most likely mechanisms of action of vitexin as a hypotensive compound are through its vasodilator and diuretic effects. So this agent could be a best new antihypertensive drug compared with present antihypertensive drugs which are in the market now. In addition to that vitexin can be used in heart failure as cardiotonic drug