experimental tumor model
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2021 ◽  
Author(s):  
Marie Bernardo ◽  
Tatiana Tolstykh ◽  
Yu-an Zhang ◽  
Dinesh S. Bangari ◽  
Hui Cao ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Felix N. Harder ◽  
Johannes Budjan ◽  
Marcel D. Nickel ◽  
Robert Grimm ◽  
Hubertus Pietsch ◽  
...  

2013 ◽  
Vol 8 (2) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Pawel T. Szymanski ◽  
Safwat A. Ahmed ◽  
Sherief Khalifa ◽  
Harukuni Tokuda ◽  
Eiichiro Ichiishi ◽  
...  

The cancer chemopreventive potential of sarcophine-diol in a chemical carcinogen initiation–promotion experimental tumor model in mice was evaluated. Sarcophine-diol, when given orally, afforded significant protection in the mouse skin cancer model initiated by the topical administration of (±)-( E)-4-methyl-2-[( E)-hydroxyamino]-5-nitro-6-methoxy-3-hexanamide (NOR-1) and promoted by 12- O-tetradecanoylphorbol-13-acetate (TPA). These findings, along with our initial reports, suggest that sarcophine-diol is an effective cancer chemopreventive agent, even when administered orally and at a very low dose and thus indicating possible potential human applications in the control of malignancy.


2006 ◽  
Vol 8 (2) ◽  
pp. 163-174 ◽  
Author(s):  
Jinsang Yoo ◽  
Seeyoung Choi ◽  
Kyung-Sun Hwang ◽  
Won-Kyung Cho ◽  
Cho-Rok Jung ◽  
...  

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