Silk Microlens Array

Optics that are capable of merging with biomaterials create a variety of opportunities for sensing disease, for therapeutics, and for augmenting brain-machine interface. The FDA has approved silk devices for sutures and reconstructive surgery. Recently, a silk product made from regenerated silk protein is FDA approved for orthopedic application, as the understanding of structure and processing technologies of silk fibroin has been improved. Here, we report a facile fabrication process to construct silk microlens array. The process includes preparation of regenerated silk solution and casting on a micropatterned poly(dimethylsiloxane) (PDMS) master. Due to the identical surface area of a unit patterned regime, the silk solution exhibits a partial wetting state in the vicinity of the silk solution–PDMS–vapor interface with same contact angle, and after drying, produces consistent radius of curvature within the microlens array. This in turn provides highly uniform focal length, focal spot diameter, and imaging performance of individual lens. Our results provide the foundation for biophotonic microlens adding new capabilities for implantable and degradable devices from regenerated silk protein.

Morphology adjustable microlens array fabricated by single spatially modulated femtosecond pulse

Silica microlens arrays (MLAs) with multiple numerical-apertures (NAs) have high thermal and mechanical stability, and have potential application prospects in 3D display and rapid detection. However, it is still a challenge to rapidly fabricate silica MLAs with a larger range of NAs and how to obtain multiple NAs in the same aperture diameter. Here, a wet etching assisted spatially modulated femtosecond laser pulse fabricating technology is proposed. In this technology, Gaussian laser pulse is modulated in the axial direction to create a pulse with a large aspect ratio, which is used to modify the silica to obtain a longer modification distance than traditional technology. After that, a microlens with a larger NA can be obtained by etching, and the NA variable range can be up to 0.06–0.65, and even under the same aperture, the variable NA can range up to 0.45–0.65. In addition, a single focus is radially modulated into several focus with different axial lengths to achieve a single exposure fabricating of MLA with multiple NAs. In characterization of the image under a microscope, the multi-plane imaging characteristics of the MLA are revealed. The proposed technology offers great potential toward numerous applications, including microfluidic adaptive imaging and biomedical sensing.

High power supercontinuum generation by dual-color femtosecond laser pulses in fused silica

High power supercontinuum (SC) is generated by focusing 800 nm and 400 nm femtosecond laser pulses in fused silica with a microlens array. It is found that the spectrum of the SC is getting broader compared with the case of single laser pulse, and the spectral energy density between the two fundamental laser wavelengths is getting significantly higher by optimizing the phase matching angle of the BBO. It exceeds μJ/nm over 490 nm range which is from 380 nm to 870 nm, overcoming the disadvantage of relative lower power in the ranges far from fundamental wavelength.