The Indiscipline of Reading

This chapter deals with the experiences and perceptions of reading within the nineteenth-century criminal system, with particular emphasis on Australian-bound transportees. It shows how attempts on the part of the authorities often fell short of their expectations, as prisoners themselves asserted their insubordination through acts of reading and writing. In particularly harsh regimes such a Norfolk Island, literacy and reading became sources of conflict among the authorities. Many took a prohibitive view of reading provision while others, like Thomas Maconachie, took a liberal attitude towards the encouragement of literacy. From transportation earlier in the period, a certain number of transportation prisoners were highly educated and often skilled in other ways. The final wave of transportation in the 1860s coincided with increased Fenian unrest in Ireland. Political prisoners in particular included a high proportion of well qualified individuals, some of them popular celebrities. Their highly literate use of reading and writing earned them the name of ‘Specials’.

Multi-phenotype genome-wide association studies of the Norfolk Island isolate implicate pleiotropic loci involved in chronic kidney disease

Chronic kidney disease (CKD) is a persistent impairment of kidney function. Genome-wide association studies (GWAS) have revealed multiple genetic loci associated with CKD susceptibility but the complete genetic basis is not yet clear. Since CKD shares risk factors with cardiovascular diseases and diabetes, there may be pleiotropic loci at play but may go undetected when using single phenotype GWAS. Here, we used multi-phenotype GWAS in the Norfolk Island isolate (n = 380) to identify new loci associated with CKD. We performed a principal components analysis on different combinations of 29 quantitative traits to extract principal components (PCs) representative of multiple correlated phenotypes. GWAS of a PC derived from glomerular filtration rate, serum creatinine, and serum urea identified a suggestive peak (pmin = 1.67 × 10–7) that mapped to KCNIP4. Inclusion of other secondary CKD measurements with these three kidney function traits identified the KCNIP4 locus with GWAS significance (pmin = 1.59 × 10–9). Finally, we identified a group of two SNPs with increased minor allele frequencies as potential functional variants. With the use of genetic isolate and the PCA-based multi-phenotype GWAS approach, we have revealed a potential pleotropic effect locus for CKD. Further studies are required to assess functional relevance of this locus.

Pedigree Derived Mutation Rate Across the Entire Mitochondrial Genome of the Norfolk Island Population

Estimates of mutation rates for various regions of the mitochondrial genome (mtGenome) vary widely, depending on whether they are inferred using a phylogenetic approach or obtained directly from pedigrees. Traditionally, only the control region, or small portions of the coding region have been targeted for analysis due to the cost and effort required to produce whole mtGenome Sanger profiles. Here, we report one of the first pedigree derived mutation rates for the entire human mtGenome. The entire mtGenome from 225 individuals originating from Norfolk Island was analysed to estimate the population mutation rate and compared against published mutation rates. These individuals were from 45 maternal lineages spanning 345 generational events. Mutation rates for various portions of the mtGenome were calculated. Nine mutations (including two transitions and seven cases of heteroplasmy) were observed, resulting in a rate of 0.063 mutations/site/million years (95% confidence interval: 0.033 – 0.118). These mutation rates are approximately 17 times higher than estimates derived from phylogenetic analysis with heteroplasmy detected in 13 samples (n=225, 5.8% individuals). Providing one of the first pedigree derived estimates for the entire mtGenome, this study provides a better understanding of mtGenome evolution and has relevance to many research fields, including medicine, anthropology and forensics.

Official and Unofficial Toponyms on Norfolk Island

Norfolk Island (South Pacific), a small external territory of Australia, has a placenaming record marked by distinct historical, settlement, and land use periods. This brief communication considers the complex nexus of official–unofficial, embedded–unembedded, and English–Norfolk Island language toponyms as a way to make better sense of the localization of toponymic knowledge and to appreciate better how such knowledge functions within a minute society intricately connected to its own largely known past and an ever changing toponymic present. The data were collected during interview fieldwork on Norfolk Island during the period 2007–2009. It concludes by putting forward a four-category division of Norfolk Island toponyms: 1) official names adhering to common colonial forms; 2) official and unofficial descriptive names; 3) unofficial names commemorating local people; 4) unofficial and esoteric names remembering local events and people. These categories appear distinct, but they are not necessarily mutually exclusive. The differentiation of processes of toponyms becoming embedded and the localization of toponymic knowledge are a possible explanation for the loss of toponymic knowledge among younger people on Norfolk Island and suggests a general ecological disconnect across time involving people, history, and events associated with Norfolk Island toponyms. The Norfolk Island official–unofficial toponym distinction is applicable to other toponymic case studies, especially situations with competing placenaming histories.