A COMPARATIVE CLINICAL STUDY OF PANCHTIKTA KSHEERA BASTI AND ASTHI SANDHANIYA DRAVYA SIDDH KSHEERA BASTI IN ASTHI KSHAYA (OSTEOPOROSIS)

According to Ayurveda, diseases occur due to Dhatuvaishamyta & Dhatusamya maintains regularity. The Ashti Dhathu is the one consecrated with the role of Shareera Dharana among the Saptha Dhathus. As-thikshaya is the condition in which there is Kshaya of Asthi Dhatu. Asthi Kshaya may be compared to Os-teoporosis, in which there is a decrease in bone mass leading to bone brittleness and fractures. Asthi Kshaya is one of Dhatu Kshaya. Due to Dhatu Kshaya there will be Vata Prakopa hence in the treatment decreased Vata Dosha along with nourishing Asthi Dhatu essential. Basti is considered as the best Treat-ment for the Vata Dosha and Asthi Ashrita Vyadhi and is known as Ardhachikitsa in Ayurveda. Ksheera Basti nourished the Asthi Dhatu and pacified there its Asharya Vata Dosha. Aim & Objective- To assess the efficacy of Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti in the man-agement of Osteoporosis. Material and Methods- Present study was undertaken on 30 patients of Osteo-porosis. Patients diagnosed Osteoporotic by Bone Mineral Density test, were randomly divided into two Groups, A and B consisting of 10 patients each. Conclusion- The study shows that the Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti are very effective in the management of Osteopo-rosis.

A COMPARATIVE CLINICAL STUDY OF PANCHTIKTA KSHEERA BASTI AND ASTHI SANDHANIYA DRAVYA SIDDH KSHEERA BASTI IN ASTHI KSHAYA (OSTEOPOROSIS)

According to Ayurveda, diseases occur due to Dhatuvaishamyta & Dhatusamya maintains regularity. The Ashti Dhathu is the one consecrated with the role of Shareera Dharana among the Saptha Dhathus. As-thikshaya is the condition in which there is Kshaya of Asthi Dhatu. Asthi Kshaya may be compared to Os-teoporosis, in which there is a decrease in bone mass leading to bone brittleness and fractures. Asthi Kshaya is one of Dhatu Kshaya. Due to Dhatu Kshaya there will be Vata Prakopa hence in the treatment decreased Vata Dosha along with nourishing Asthi Dhatu essential. Basti is considered as the best Treat-ment for the Vata Dosha and Asthi Ashrita Vyadhi and is known as Ardhachikitsa in Ayurveda. Ksheera Basti nourished the Asthi Dhatu and pacified there its Asharya Vata Dosha. Aim & Objective-To assess the efficacy of Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti in the man-agement of Osteoporosis. Material and Methods- present study was undertaken on 30 patients of Osteo-porosis. Patients diagnosed Osteoporotic by Bone Mineral Density test, were randomly divided into two Groups, A and B consisting of 10 patients each. Conclusion-The study shows that the Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti are very effective in the management of Osteopo-rosis.

Management of Osteoporosis in Survivors of Adult Cancers With Nonmetastatic Disease: ASCO Clinical Practice Guideline

PURPOSE The aim of this work is to provide evidence-based guidance on the management of osteoporosis in survivors of adult cancer. METHODS ASCO convened a multidisciplinary Expert Panel to develop guideline recommendations based on a systematic review of the literature. RESULTS The literature search of the 2018 systematic review by the US Preventive Services Task Force in the noncancer population was used as the evidentiary base upon which the Expert Panel based many of its recommendations. A total of 61 additional studies on topics and populations not covered in the US Preventive Services Task Force review were also included. Patients with cancer with metastatic disease and cancer survival outcomes related to bone-modifying agents are not included in this guideline. RECOMMENDATIONS Patients with nonmetastatic cancer may be at risk for osteoporotic fractures due to baseline risks or due to the added risks that are associated with their cancer therapy. Clinicians are advised to assess fracture risk using established tools. For those patients with substantial risk of osteoporotic fracture, the clinician should obtain a bone mineral density test. The bone health of all patients may benefit from optimizing nutrition, exercise, and lifestyle. When a pharmacologic agent is indicated, bisphosphonates or denosumab at osteoporosis-indicated dosages are the preferred interventions.

Repeat Bone Mineral Density Screening and Osteoporotic Fracture Prediction

This chapter, found in the bone, joint, and extremity pain section of the book, provides a succinct synopsis of a key study examining the need for repeat bone densitometry screening and prediction of fractures from osteoporosis. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that a repeat bone mineral density test within 4 years adds little additional value beyond the baseline test when assessing hip fracture risk. Moreover, a repeat test within 4 years may not improve fracture risk stratification used for clinical management of osteoporosis. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

Nonlinear Effects of Bone Damping on Human Postural Balance

Osteoporosis is a common disease in women over the age of 50. The detection of this disease is done by an expensive bone mineral density test using dual energy x-ray absorpiometry. Osteoporosis patients are at a high risk of bone fracture under daily living conditions. Previous studies have shown that natural shock absorption capability of human body suffering from osteoporosis is significantly impaired. This study is to develop an understanding of nonlinear effects of osteoporosis on human postural balance via computational models developed to capture changes in the shock absorption capabilities of human musculoskeletal system in osteoporosis patients. This paper uses a previously published, time delayed model of human postural balance by simulating the effect of osteoporosis via changes in damping factor. Numerical studies are presented and results interpreted to capture and highlight the nonlinear effects of osteoporosis on the dynamics postural balance response. This approach, upon further clinical evaluation can result in utilization of human postural balance test and the corresponding non-invasive Bone Shock Absorption test and measurement techniques for detection of osteoporosis.