Indirect modulation of human visual memory

Conditions in which memories become maladaptive have inspired extensive research geared to modulate memory by targeting it directly and explicitly. Given limitations of direct memory modulation, we asked the following: can the target memories be modulated indirectly? To address this question, we uniquely targeted visual memories, and leveraged a paradigm utilizing instructions to either forget or remember newly encoded memories. We used a multi-domain approach, and applied the instructions to embedded verbal information presented during encoding (words), with the intention to indirectly modulate recognition of the target visual context memory itself (pictures). Accordingly, participants were presented with two lists of words, where each word was preceded and followed by pictures. Participants were instructed to either remember or forget the first list of words. As expected, the instruction to either remember or forget the words differentially influenced word memory strength. Importantly, the instruction regarding the words, indirectly modulated picture memory strength. Better memory for words resulted in reduced picture memory strength and vice versa, with the instruction to remember the words reducing picture memory strength. Together with a negative correlation between word and picture memory strength, the results suggest a competition for shared resources between memory for content and context. These findings may open new avenues to indirectly modulate maladaptive memories.

What I Like Is What I Remember: Memory Modulation and Preferential Choice

Memory is a crucial component of everyday decision making, yet little is known about how memory and choice processes interact, and whether or not established memory regularities persist during memory-based decision making. In this paper, we introduce a novel experimental paradigm to study the differences between memory processes at play in standard list recall versus in preferential choice. Using computational memory models, fit to data from two pre-registered experiments, we find that some established memory regularities (primacy, recency, semantic clustering) emerge in preferential choice, whereas others (temporal clustering) are significantly weakened relative to standard list recall. Notably, decision-relevant features, such as item desirability, play a stronger role in guiding retrieval in choice. Our results suggest memory processes differ across preferential choice and standard memory tasks, and that choice modulates memory by differentially activating decision-relevant features such as what we like.