<p>&#160;We describe the very local interstellar medium (VLISM)<br>immediately outside of the outer heliosphere. The VLISM consists&#160;<br>of four partially ionized clouds - the Local Interstellar Cloud (LIC),&#160;<br>G cloud, Blue cloud, and Aql cloud that are in contact with the outer&#160;<br>heliosphere, and ionized gas produced by extreme-UV radiation&#160;<br>primarily from the star Epsilon CMa. We construct the&#160;<br>three-dimensional shape of the LIC based on interstellar line&#160;<br>absorption along 62 sightlines and show that in the direction of&#160;<br>Epsilon CMa, Beta CMa, and Sirius B the neutral hydrogen column&#160;<br>density from the center of the LIC looking outward is a minimum.&#160;<br>We call this region the ``hydrogen hole''. In this direction, the&#160;<br>presence of Blue cloud absorption and the absence of LIC absorption&#160;<br>can be simply explained by the Blue cloud lying just outside of the&#160;<br>heliosphere. We propose that the outer edge of the Blue cloud is a&#160;<br>Str\"omgren shell driven toward the heliosphere by high pressures in&#160;<br>the H II region. The outer edges of other clouds facing Epsilon CMa&#160;<br>are likely also Stromgren shells. Unlike previous models, the LIC<br>surrounds less than half of the heliosphere.</p><p>We find that the vectors of neutral and ionized helium flowing<br>through the heliosphere are inconsistent with the mean LIC flow&#160;<br>vector and describe several possible explanations. The ionization<br>of nearby intercloud gas is consistent with photo-ionization by&#160;<br>Epsilon CMa and hot white dwarfs without requiring additional&#160;<br>sources of ionization or million degree plasma. In the upwind&#160;<br>direction, the heliosphere is passing through an environment of&#160;<br>several LISM clouds, which may explain the recent influx of&#160;<br>interstellar grains containing 60Fe from supernova ejecta measured&#160;<br>in Antarctica snow. The Sun will leave the outer partof the LIC&#160;<br>in less than 1900 years, perhaps this year, to either enter the&#160;<br>partially ionized G cloud or a highly ionized intercloud layer.&#160;<br>The heliosphere will change in either scenario. An instrumented&#160;<br>deep space probe sending back in situ plasma and magnetic field&#160;<br>measurements from 500-1,000 AU is needed to understand the&#160;<br>heliosphere environment rather than integrated data along the&#160;<br>sightlines to stars. &#160;</p>