The Social Construction of Perceptual Categories

In this article I shall argue that the categories a subject employs to codify her perceptions are emergent elements of the social niche her community inhabits. Hence, I defend the claim that categories are primarily elements of the social ontology a certain subject experiences. I then claim that public representations (e.g. icons) shared in a social niche play a crucial regulative role for the members of that community: in fact, they offer a rule (a canon) to conceive a certain type or a certain category, e.g. ‘movement’, ‘time’ or ‘space’. In this sense, categories function as normative elements.

Some clarifications on critical and Indigenous psychologies

This comment responds to Held’s (2020) analyses of Indigenous and critical psychologies, not by providing line-for-line refutations of arguments, but by laying out some of the larger issues in those areas of research and practice. The argument clarifies assumptions and misunderstandings by looking at the relationship between critical and Indigenous psychologies, power and violence, objectivity, and the regulative role of prepositions. It is hoped that a clearer and broader understanding of those psychologies can emerge.

What is this Thing Called ‘Scientific Knowledge’? – Kant on Imaginary Standpoints And the Regulative Role of Reason

In this essay I analyse Kant’s view on the regulative role of reason, and in particular on what he describes as the ‘indispensably necessary’ role of ideas qua foci imaginarii in the Appendix. I review two influential readings of what has become known as the ‘transcendental illusion’ and I offer a novel reading that builds on some of the insights of these earlier readings. I argue that ideas of reason act as imaginary standpoints, which are indispensably necessary for scientific knowledge by making inter-conversational agreement possible. Thus, I characterise scientific knowledge as a distinctive kind of perspectival knowledge. This novel reading can illuminate the role of reason in complementing the faculty of understanding and sheds light on the apparent dichotomy between the first and the second part of the Appendix. More to the point, this novel reading takes us right to the heart of what scientific knowledge is, according to Kant, and how it differs from bogus knowledge and opinion.

On the regulative role of the glutamate receptor in mitochondria

The purpose of this work was to study the regulative role of the glutamate receptor found earlier in the brain mitochondria. In the present work a glutamate-dependent signaling system with similar features was detected in mitochondria of the heart. The glutamate-dependent signaling system in the heart mitochondria was shown to be suppressed by γ-aminobutyric acid (GABA). The GABA receptor presence in the heart mitochondria was shown by golding with the use of antibodies to α- and β-subunits of the receptor. The activity of glutamate receptor was assessed according to the rate of synthesis of hydrogen peroxide. The glutamate receptor in mitochondria could be activated only under conditions of hypoxic stress, which in model experiments was imitated by blocking Complex I by rotenone or fatty acids. The glutamate signal in mitochondria was shown to be calcium- and potential-dependent and the activation of the glutamate cascade was shown to be accompanied by production of hydrogen peroxide. It was discovered that H2O2 synthesis involves two complexes of the mitochondrial electron transfer system – succinate dehydrogenase (SDH) and fatty acid dehydrogenase (ETF:QO). Thus, functions of the glutamate signaling system are associated with the system of respiration-glycolysis switching (the Pasteur-Crabtree) under conditions of hypoxia.