The search for new forms of personal expression in the era of postmodernism

The urgency of the studied problem is due to the fact that reveals one of the most popular and fashionable areas of philosophy of the XXI century - the philosophy of postmodernism, in the context of which the coronavirus discourse fits, which continues to deepen and fill with new content. Due to the huge number of problems of digital transformation of human existence, the concepts of postmodern society in the context of digitalization should be explored in order to overcome the negative consequences of coronavirus existence. The aim of the article is to conceptualize the philosophy of postmodernism, which unfolds, on the one hand, as a search for new forms of creative self-expression, and on the other, as a crisis of philosophical knowledge. The objectives of the study include the analysis of the concepts of postmodern reality, which is based on the formation of a new system of categories and concepts as a system of ways of constructing a new being - postmodernism, deconstructivism, simulacrum. This system of concepts includes a set of methods of cognition of reality - ontological-metaphysical, logical-axiological, critical-existential to understand the essence and existence of man, understanding their correlations and attributive system parameters, structure, substrate, characteristic of understanding a complex society. An ambivalent and contradictory current is represented, which has spread to many areas - politics, religion, science in search of an assessment of the cognitive capabilities of man and his place in the modern world. The materials of the article are of practical value for in-depth understanding of postmodern philosophy, which is closely related to the problems of coronavirus and post-coronavirus life. It is concluded that postmodernity is a big process of losing the sensation of history and the meaning of a person, which led to the destruction of history, a crisis of philosophical knowledge in the era of digitalization, in which the original no longer makes sense, and the model of a veiled copy prevails.

Hydroxyapatite Particle Density Regulates Osteoblastic Differentiation Through β-Catenin Translocation

Substrate surface characteristics such as roughness, wettability and particle density are well-known contributors of a substrate's overall osteogenic potential. These characteristics are known to regulate cell mechanics as well as induce changes in cell stiffness, cell adhesions, and cytoskeletal structure. Pro-osteogenic particles, such as hydroxyapatite, are often incorporated into a substrate to enhance the substrates osteogenic potential. However, it is unknown which substrate characteristic is the key regulator of osteogenesis. This is partly due to the lack of understanding of how these substrate surface characteristics are transduced by cells. In this study substrates composed of polycaprolactone (PCL) and carbonated hydroxyapatite particles (HAp) were synthesized. HAp concentration was varied, and a range of surface characteristics created. The effect of each substrate characteristic on osteoblastic differentiation was then examined. We found that, of the characteristics examined, only HAp density, and indeed a specific density (85 particles/cm2), significantly increased osteoblastic differentiation. Further, an increase in focal adhesion maturation and turnover was observed in cells cultured on this substrate. Moreover, β-catenin translocation from the membrane bound cell fraction to the nucleus was more rapid in cells on the 85 particle/cm2 substrate compared to cells on tissue culture polystyrene. Together, these data suggest that particle density is one pivotal factor in determining a substrates overall osteogenic potential. Additionally, the observed increase in osteoblastic differentiation is a at least partly the result of β-catenin translocation and transcriptional activity suggesting a β-catenin mediated mechanism by which substrate surface characteristics are transduced.

Identifikasi Habitat Fisik Sungai dan Keberagaman Biotilik Sebagai Indikator Pencemaran Air Sungai Musi Kota Palembang

Latar belakang: Sungai menjadi salah satu pemasok air terbesar untuk kebutuhan mahluk hidup yang memiliki fungsi penting bagi kehidupan manusia. Sungai Musi merupakan sumberdaya alam yang menjadi salah satu jalur utama perdagangan dan pemasok air terbesar bagi penduduk Sumatera Selatan. Akan tetapi kondisi Sungai Musi telah mengalami perubahan disebabkan saratnya pemukiman dan industri. Aktivitas ini akan berdampak terhadap kondisi fisik sungai serta habitat hewan air yang menghuni perairan. Penelitian ini bertujuan untuk mengidentifikasi habitat fisik sungai serta keberagaman biotilik sebagai indicator pencemaran perairan Sungai Musi Kota Palembang.Metode: Penilaian pencemaran perairan ditentukan dengan melihat indicator habitat fisik sungai dan keberagaman biotilik sungai melalui biota makro invertebrata, serta menggunakan metode wawancara.Hasil: Hasil penelitian menunjukkan bahwa kualitas air perairan Sungai Musi di Wilayah Sebrang Ulu I dan II berada dalam kondisi buruk, terlihat dari hasil observasi yang menunjukkan bahwa mayoritas (lebih dari 70%) parameter berada pada indicator buruk (C). Serta hanya ditemukan satu biota air yaitu ikan. Hasil laboratorium menunjukkan nilai TSS di kedua titik melebihi nilai standar normal, sedangkan nilai COD dan BOD masih di bawah nilai standar normal.Simpulan: Perairan Sungai Musi di Wilayah Sebrang Ulu I dan II, termasuk ke dalam kategori Buruk (C). Hal ini didasarkan hasil pemeriksaan habitat fisik sungai, pemeriksaan hewan biotilik Serta pemeriksaan kadar TSS, BOD dan COD. ABSTRACTTitle:Identification of thePhysicalHabitatandDiversityRiverBiotilikas Indicatorsof Water PollutionMusi RiverPalembangBackground: Rivers became one of the largest water supplier for the needs of living things that have important functions for human life. Musi River is a natural resource that is becoming one of the main lines of trade and the largest supplier of water for the residents of South Sumatra. But conditions have changed Musi River caused there are more residential and industrial. This activity will have an impact on the physical condition of the river as well as the habitat of aquatic animals that inhabit the waters. This study aims to identify the physical habitat of the river as well as the diversity biotilik as an indicator of pollution of the waters of the Musi River Palembang. Method: The assessment of water pollution is determined by observing the indicator of the river's physical habitat by looking at the baseline substrate characteristic indicator consisting of 6 (six) parameters and indicators of river health disturbance factor consisting of 12 (twelve) parameters and biotenic diversity of the river through invertebrate macro biota, using interview methods to the local community.Result: The results showed that the water quality of the waters of the Musi River in Sebrang Ulu I and II were in poor condition, visible from the observation showed that the majority (over 70%) the parameters that were in bad indicator (C). As well as just founded the water biota was fish. The laboratory result showes the value of TSS in the second point of exceeding the normal standard, while the COD and BOD values were still below the normal standard. Conclusion: The waters of the Musi River in Sebrang Ulu I and II are included in the Bad category (C). This is based on the results of examination of the river's physical habitat, examination of biotic animals and examination of TSS, BOD and COD levels

Produksi Dan Laju Dekomposisi Serasah Mangrove (Rhizophora Sp.) Di Desa Durian Dan Desa Batu Menyan Kecamatan Padang Cermin Kabupaten Pesawaran

ABSTRACT Mangrove litter leaf represent the organic substance supplier towards fertility of mangrove ecosystem, that able to support the mortal life within. The area of forest of mangrove represent the nursery ground, feeding ground, and area of spawning ground for various fish type, prawn and other biota sea and also as producer of amount of detritus for plankton as main foods source of the sea. The objectives of this research were to know production and decomposition rate of mangrove litter leaf in the mangrove ecosystem of Durian Village and Batu Menyan Village, Padang Cermin subdistrict, Pesawaran regency. Data was analysed by calculating the dry weight mean of litter leaf production and to counting decomposition rate was using the exponential rank function or from absolute decomposition percentage of litter leaf per day. This research was conducted in two place (station) based on the difference of substrate characteristic. The research conducted from October to December 2013. The productivity of mangrove’s litter leaf in both places is 0,56 g/m2/day, where the leaf organ gave the higgest contribution, (66%), stick and branch (14%), flower and fruit (20%). Decomposition rate of mangrove litter leaf showed that at the second station ( 0,20 g / hr) was faster than the first station ( 0,19 g / hr). Keywords : Decomposition rate, litter leaf litter leaf, mangrove, production