Rapid detection of free and bound toxins using molecularly imprinted silica/graphene oxide hybrids

A miniaturised electrochemical sensor integrating a molecularly imprinted silica/graphene oxide hybrid with non-equilibrium pulse amperometry for the fast quantification of free and bound toxins.

Selective Optosensing of Aminoimidazo-Azaarenes (AIAs) by CdSe/ZnS Quantum Dots-Embedded Molecularly Imprinted Silica Gel

Background: The approach for the determination of aminoimidazo-azaarenes (AIAs) is urgent required due to their mutagenic activity and potential carcinogenicity. For this purpose, a CdSe/ZnS quantum dots (CdSe/ZnS QDs) - embedded molecularly imprinted silica gel with high selectivity and sensitivity was successfully prepared and applied to analyze such target. Methods: Herein, CdSe/ZnS QDs acted as the fluorescent probe, and molecularly imprinted silica gel as recognition probe was synthesized on the surface of QDs via sol-gel method. 2-Aminobenzimidazole, which has a similar structure with AIAs, as well as low cost and low toxicity, was selected as the dummy template. Results: The material has a high imprinting factor (IF=6.15); the linear range of CdSe/ZnS@MIP as a fluorescent sensing material for AIAs is 0.5-20.0 μg L -1 with the limit of detection (LOD) of 0.25 μg L -1 (3σ/s). Moreover, the fluorescent materials have been further applied to determine AIAs in beef floss and grilled fish fillet with satisfactory recoveries (82.8-110.8 %), and the relative standard deviation (RSD) is < 5.5%. Conclusion: The proposed CdSe/ZnS QDs-embedded molecularly imprinted silica gel can be used to easily and selectively detect AIAs.

Dual roles of 3-aminopropyltriethoxysilane in preparing molecularly imprinted silica particles for specific recognition of target molecules

A novel strategy was developed for preparing highly selective molecularly imprinted polymers using 3-aminopropyltriethoxysilane as both a functional monomer and catalyst.