velvet antler polypeptide
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2020 ◽  
Vol 11 (11) ◽  
pp. 9752-9763
Author(s):  
Lihua Li ◽  
Fan Yang ◽  
Rongjun Jia ◽  
Pengfei Yan ◽  
Liman Ma

The present study aims to examine the protective effects and mechanism of a velvet antler polypeptide (VAP) against lithocholic acid (LCA)-induced cholestatic liver injury in mice.





2017 ◽  
Vol 37 (3) ◽  
pp. 308-313
Author(s):  
Zhang Lihong ◽  
Zhuang Zhihong ◽  
Sun Yanan ◽  
Ma Shuhua ◽  
Yang Weifeng ◽  
...  


2016 ◽  
Vol 18 (4) ◽  
pp. 613 ◽  
Author(s):  
Zhi-Jun Zang ◽  
Hong-Feng Tang ◽  
Ying Tuo ◽  
Wei-Jie Xing ◽  
Su-Yun Ji ◽  
...  




2013 ◽  
Vol 380-384 ◽  
pp. 4295-4298
Author(s):  
Wen He Zhu ◽  
Jun Jie Xu ◽  
Wei Zhang ◽  
Yan Li ◽  
Xiao Jing Lu ◽  
...  

A highly osteogenic hybrid bioabsorbable scaffold was developed for bone reconstruction. Though the use of a bioabsorbable collagen and chitosan scaffold for loading velvet antler polypeptide to repair bone defect and drug treatment. Velvet antler polypeptide and collagen were extracted for developing the compounded material. The SEM results show that the collagen and chitosan scaffold maintain the natural three dimensional network structures. The cell proliferation experiment result show that the can promote the osteoblast proliferation for a long time . These results indicated that this compound scaffold can sustainable to release drug and is a good material in bone defect and drug treatment.





2006 ◽  
Vol 53 (2) ◽  
pp. 395-397 ◽  
Author(s):  
Shu-Wen Guan ◽  
Leng-Xin Duan ◽  
Yuan-Yuan Li ◽  
Ben-Xiang Wang ◽  
Qiu-Li Zhou

A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg x L(-1) and 5-80 mg x L(-1), respectively).



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