Work conditions of main occupational groups in production of secondary precious metals, associated with exposure to multi-component industrial aerosol and heating microclimate, determine high level of relative risk of dermatologic diseases development in the workers. Etiologic share of occupational factors in formation of skin and subcutaneous tissue diseases reaches 88,8% for certain nosologies — that proves high degree of their occupational conditionality. Te authors determined length of service for risk of occupationally conditioned dermatologic diseases. Findings are that dermatologic diseases influence significantly the parameters of life quality assessed via integral dermatologic indexes. Randomized clinical study proved efficiency of emollients as addition to present treatment and prevention standards for chronic allergic dermatoses and eczema in workers engaged into secondary precious metals production.