Leprosy suspect presenting at a chest clinic

Leprosy is an ancient ailment, also known as Hansen’s disease. It primarily involves the superficial peripheral nerves, skin, upper respiratory tract mucosa, eyes, bones and testicles, but not the lungs. Although leprosy patients are not included in the study area of pulmonology, here we present an undiagnosed leprosy patient with a history of smoking, who was referred owing to upper respiratory tract symptoms and bilateral pleural effusions. From this undiagnosed case, we would like to draw specific attention of pulmonologists, since a patient with leprosy can present in this way due to hypoalbuminemia resulting from a systemic inflammatory state, which may then progress to sepsis. Collaboration of different specialists may be required to clinch extra-neurological and extra-cutaneous features of leprosy.

The First Report of Diversity Analyses of Skin Microbiome In Indonesian Leprosy Patient

BackgroundSkin microbiome is quiet diverse. There are several factors influencing the skin microbiome, such as skin diseases. However, the effects of leprosy on the skin microbiome remain unclear and there are only a few studies about skin microbiome on leprosy. The aim of this study was to investigate the alpha diversity of skin microbiome on lesional site of multibacillary (MB) leprosy patients who visited the top referral hospital in West Java Indonesia. Here in this study we characterize the skin microbiome in leprosy patient in compared to healthy individual by using next generation 16S rRNA sequencing. A total 18 skin swab samples were collected from 18 samples (14 leprosy patients, 4 healthy individuals).ResultsTaxonomic analysis of leprous skin lesions revealed main five phyla: Proteobacteria, Actinobacteria, Firmicutes, Bacteroidetes, and Cyanobacteria. Proteobacteria and Firmicutes were overrepresented in leprosy patients, while Actinobacteria, Bacteroidetes, and Cyanobacteria were diminished in leprosy patients compared to healthy individuals. The main five genera in leprous skin lesions were Staphylococcus, Acinetobacter, Corynebacterium, Micrococcus, and Propionibacterium. Staphylococcus, Acinetobacter, and Micrococcus were enriched in leprosy patients, while Corynebacterium and Propionibacterium which have a protective role in normal skin, were diminished in leprosy patients when compared with healthy individuals. Twenty-five species were found in leprous skin lesions that were not typical in human skin and considered as potentially pathogenic. The alpha diversity analysis showed that leprous skin lesions is less diverse than that of the healthy skin microbiome.ConclusionAs a conclusion, the skin microbiome on lesional site of leprosy patient show alteration and less diverse compare to healthy individuals. This suggest that leprosy can affects skin microbiome profile or otherwise.

Gambaran tingkat kemandirian personal Hygien pada penderita kusta

Personal hygiene is one of actiontomaintainthe clean lines sandhealthy of a personfor physical and psychological wellfare. Fulfillment ofpersonal hygiene required for individual comfort,safety, and health. Personal hygiene needed bothinpeople who is health and in people who is sick. Mostof the respondents had less personal hygiene. Thepurpose of this study is to describethe degree ofindependence of personal hygienein leprosypatients. This research method is descriptive withsurvey approach. The variable is leprosy personalhygiene. The number of samples is 15 respondentsof lepers. The sampling usingthe total population, theinstrument is a questionnaire.The results of the studymost of therespondents have less personalhygiene13 people (86.66%). Then, it can bedescribed that personal hygiene of lepers at theTangungguh village is notqualify inpersonal hygieneneeds. With the results of this study are expectedthat leprosy patients can understand about an effortin clean living to decrease leprosy. And for healthworkers and related institution related agenciesshould further expandthe study of efforts to increasepublic understanding of leprosy patient primarily onefortsinclean living. For further research canbeusedas a referencein the development ofsubsequentscientific work.