breast cancer metastasis suppressor
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2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 235-235
Author(s):  
Moon-Cheol Shin ◽  
Jae-young Choi ◽  
In-Cheol Cho ◽  
Byoung Chul Yang ◽  
Nam Young Kim

Abstract The purpose of this study was to compare the changes of teat number traits of Jeju native pig (JNP) and Landrace varieties according to the breast cancer metastasis-suppressor 1-like (BRMS1L) genotype. The number of teat varies according to the single-base polymorphism with a G or A base 1,087 from the start codon ATG in the exon 1 region of the BRMS1L gene. The total teat number was examined at birth for 28 JNPs and 72 Landraces, and the BRMS1L genotype was analyzed by Pyrosequencing. As a result, the genotyping frequency of JNP was 1 A / A type, 9 A / G type, and 18 G / G type, whereas, on the contrary, Landrace had 70 A / A type, 2 A / C type, and C / C was identified as 0 heads. The total teat number was between the two varieties was 13.32 ± 0.95 and 14.51 ± 1.03, respectively (P < 0.001). According to genotypes in Jeju native pig breeds, the total number of nipples was 15 A / A, 14.0 ± 0.82 A / G, and 12.89 ± 0.74 G / G (P < 0.018). Conversely, Landrace was 14.54 ± 1.02 A / A and 13.5 ± 0.5 A / G. As a result of the above study, the frequency of varieties and genotypes was found to have a significant effect on the difference in nipple count. Based on the results of this study, if the improvement of Jeju native pigs is to be carried out, it is expected that the number of nipples will increase and the mammalian capacity will increase.


2019 ◽  
Author(s):  
BL Eckhardt ◽  
A Redfern ◽  
EK Sloan ◽  
Y Cao ◽  
BS Parker ◽  
...  

Breast Cancer ◽  
2018 ◽  
Vol 26 (2) ◽  
pp. 215-228 ◽  
Author(s):  
Zahra Sadat Hashemi ◽  
Mehdi Forouzandeh Moghadam ◽  
Saeed Khalili ◽  
Mahlegha Ghavami ◽  
Fatemeh Salimi ◽  
...  

Mastology ◽  
2018 ◽  
Vol 28 (s1) ◽  
pp. 96-96
Author(s):  
Rebeka Tomasin ◽  
◽  
Ana Carolina Baptista Moreno Martin ◽  
Márcia Regina Cominetti ◽  
Kaylene Simpson ◽  
...  

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