Environmentally Friendly Polymer Compositions with Natural Amber Acid

Few scientific reports have suggested the possibility of using natural phenolic acids as functional substances, such as stabilizers for polymeric materials. The replacement of commercial stabilizers in the polymer industry can be beneficial to human health and the environment. The aim of this study was to obtain biodegradable composition of polylactide (PLA) and polyhydroxyalkanoate (PHA) with natural amber (succinic) acid. The materials were subjected to controlled thermooxidation and solar aging. The research methodology included thermal analysis, examination of surface energy, mechanical properties and spectrophotometric analysis of the color change after aging. The samples of aliphatic polyesters containing from 1 to 2 parts by weight of succinic acid were characterized by increased resistance to oxidation (DSC analysis). Natural acid, preferably at a concentration of 1–1.5 parts by weight, acted as a stabilizer in the polymer compositions. On the other hand, materials that had amber acid above 2 parts by weight added were more susceptible to oxidation (DSC). They also showed the lowest aging coefficients (K). The addition of acid at 2.5–4 parts by weight caused a pro-oxidative effect and accelerated aging. By adding amber acid to PLA and PHA, it is possible to design their time in service and their overall lifetime.

THE ANTIMICROBIAL BIODEGRADABLE COMPOSITION BASED ON HIGH-MOLECULAR WEIGHT POLYVINYLPYRROLIDONE FOR THE PROPHYLAXIS OF EXPERIMENTAL OSTHEOMYELITIS

The aim of study was to evaluate the efficacy of antimicrobial composition of amikacin with dioxydin and polyvinylpyrrolidone as a biodegradable prolonging agent for the post-surgery infections prophylaxis. The data obtained show the efficacy of the amikacin combination with dioxydin based on high-molecular weight polyvinylpyrrolidone and an opportunity to it's application for the post-surgery infections prophylaxis in traumatology, orthopedics and other surgery areas.